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	题名	作者	年代	出处	被引量
1	Role of monocytes and macrophages in experimental and human acute liver failure显示文摘Acute liver failure (ALF) is a devastating clinical syndrome characterised by progressive encephalopathy, coagulopathy, and circulatory dysfunction, which commonly leads to multiorgan failure and death. Central to the pathogenesis of ALF is activation of the immune system with mobilisation of cellular effectors and massive production of cytokines. As key components of the innate immune system, monocytes and macrophages are postulated to play a central role in the initiation, progression and resolution of ALF. ALF in humans follows a rapidly progressive clinical course that poses inherent difficulties in delineating the role of these pivotal immune cells. Therefore, a number of experimental models have been used to study the pathogenesis of ALF. Here we consider the evidence from experimental and human studies of ALF on the role of monocytes and macrophages in acute hepatic injury and the ensuing extrahepatic manifestations, including functional monocyte deactivation and multiple organ failure.	Lucia A Possamai Charalambos Gustav Antoniades Quentin M Anstee Alberto Quaglia Diego Vergani Mark Thursz Julia Wendon	2010	World Journal of Gastroenterology2010，16，15：	12
2	Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients with Acute Alcoholic Hepatitis显示文摘	Lee J.L. Markwick Antonio Riva Jennifer M. Ryan Helen Cooksley Elena Palma Tom H. Tranah Godhev K. Manakkat Vijay Nikhil Vergis Mark Thursz Alex Evans Gavin Wright Sarah Tarff John O’Grady Roger Williams Debbie L. Shawcross Shilpa Chokshi	2014	Gastroenterology2014，，：	2
3	Genetic susceptibility in chronic viral hepatitis 显示文摘	Thursz M	2001	Antivirat Re s2001，52，2：	1
4	The role of hypercoagulability in liver fi- brogenesis显示文摘	Anstee QM Thursz MR	2011	Clin Res Hepatol Gastroenterol2011，35，89：	1
5	Birth order and risk of hepatocellular carcinoma in chronic carriers of hepatitis B virus: a case–control study in The Gambia显示文摘	Yusuke Shimakawa Maud Lemoine Christian Bottomley Harr Freeya Njai Gibril Ndow Abdoulie Jatta Saydiba Tamba Lamin Bojang Makie Taal Ousman Nyan Umberto D’Alessandro Ramou Njie Mark Thursz Andrew J. Hall	2015	Liver Int2015，，10：	1
6	Pros and cons of genetic association studies in hepatitisB显示文摘	Thursz M	2004	Hepatology2004，40，2：	1
7	Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia显示文摘	Thursz MR Kwiatkowski D Allsopp CE Greenwood BM Thomas HC Hill AV	1995	N Engl J Med1995，332，16：	1
8	Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene显示文摘	Bellamy R Ruwende C Corrah T McAdam KP Thursz M Whittle HC Hill AV	1999	J Infect Dis1999，179，3：	1
9	Genetic susceptibility in chronic viral hepatitis 显示文摘	Thursz M	2001	Antiviral Res2001，52，：	1
10	Hepatitis Bvirus precore/core variation and interferon therapy 显示文摘	FATTOVICH G MCINTYRE G THURSZ M	1995	Hepatology1995，22，5：	1
11	Association between an MHC class Ⅱ allele and clearance of hepatitis B virus in the Gambia显示文摘	Thursz M R Kwiatkowski D Allspp C E	1995	N Engl Med1995，332，16：	1
12	Quantitative versus morphological assessment of liver fibrosis: semi -quantitative scores are more robust than digital image fibrosis area estimation 显示文摘	Wright M Thursz M Pullen R	2003	Liver Int2003，23，1：	1
13	Interleukin-10 promoter polymorphisms and the outcome of hepatitis C virus infection显示文摘	Susanne Knapp Branwen J. W. Hennig Angela J. Frodsham Lyna Zhang Simon Hellier Mark Wright Rob Goldin Adrian V. S. Hill Howard C. Thomas Mark R. Thursz	2003	Immunogenetics2003，，6：	1
14	Association between an MHC class Ⅱ allele and clearance of hepatitis B virus in the Gambia显示文摘	Thursz MR Kwiatkowski D Allsopp CE		0，，：	1
15	Association between an MHC class allele and clearance of hepatitis B virus显示文摘	Thursz M R Kwiatkowski D Allsopp C E	1995	N Eng J Med1995，332，16：	1
16	Association between an MHC Class ⅡAllele and Clearance of Hepatitis B Virus in the Gambia显示文摘	Thursz MR Kwiatkowski D Allsopp CEM	1995	N Eng J Med1995，332，16：	1
17	Genetic susceptibility in chronic viral hepatitis 显示文摘	THURSZ M	2001	Antiviral Res2001，52，11：	1
18	Viral hepatitis and the global burden of disease, a need to regroup显示文摘	COOKE GS LEMOINE M THURSZ M	2013	J Viral Hepat2013，20，9：	1
19	Genetic susceptibility in chronic viral hepatitis显示文摘	Thursz M	2001	Antiviral Res2001，52，2：	1
20	Host genetic factors influencing the outcome of hepatitis显示文摘	Thursz MR	1997	J Viral Hepat1997，4，：	1

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