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| 1 | High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test显示文摘AIM:To assess the vitamin A status of patients with Crohn's disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic stores.Body composition was performed by densitometry by dual-energy X-ray absorptiometry.Vitamin A dietary intake was assessed from a semiquantitative food frequency questionnaire.RESULTS:This study included 38 CD patients and 33 controls.Low serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency.There was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel resections.CONCLUSION:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods. | Márcia Soares-Mota Tianny A Silva Luanda M Gomes Marco AS Pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman | 2015 | World Journal of Gastroenterology2015,21,5: | 4 |
| 2 | Does active Crohn′s disease have decreased intestinal antioxidant capacity?显示文摘 | Marco Antonio S. Pinto Márcia Soares-Mota S. Lopes Sálua T.O. Bastos Carolina L.L. Reigada Rafael F. Dantas Jaime C.B. Neto Aderval S. Luna Kalil Madi Tiago Nunes Cyrla Zaltman | 2012 | Journal of Crohn’s and Colitis2012,,: | 1 |
| 3 | Smoking and gastric cancer: systematic review and meta-analysis of cohort studies显示文摘 | Ricardo Ladeiras-Lopes Alexandre Kirchhofer Pereira Amanda Nogueira Tiago Pinheiro-Torres Isabel Pinto Ricardo Santos-Pereira Nuno Lunet | 2008 | Cancer Causes & Control2008,,7: | 1 |
| 4 | Osteomodulin downregulation is associated with osteoarthritis development显示文摘Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis(OA), and osteomodulin(OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However, the functions of OMD remain poorly understood, specifically in vivo. We used Omd knockout and overexpressing male mice and mutant zebrafish to study its roles in bone and cartilage metabolism and in the development of OA. The expression of Omd is deeply correlated with bone and cartilage microarchitectures affecting the bone volume and the onset of subchondral bone sclerosis and spontaneous cartilage lesions. Mechanistically, OMD binds to RANKL and inhibits osteoclastogenesis, thus controlling the balance of bone remodeling. In conclusion, OMD is a key factor in subchondral bone sclerosis associated with OA. It participates in bone and cartilage homeostasis by acting on the regulation of osteoclastogenesis. Targeting OMD may be a promising new and personalized approach for OA. | Jérémie Zappia Qiao Tong Renée Van der Cruyssen Frederique MFCornelis Cécile Lambert Tiago Pinto Coelho Juliane Grisart Erika Kague Rik JLories Marc Muller Dirk Elewaut Chrissy LHammond Christelle Sanchez Yves Henrotin | 2023 | Bone Research2023,11,4: | 0 |
| 5 | A Simulation of Market-based Non-frequency Ancillary Service Procurement Based on Demand Flexibility显示文摘This paper proposes a novel approach for the provision of non-frequency ancillary service(AS)by consumers connected to low-voltage distribution networks.The proposed approach considers an asymmetric pool-based local market for AS negotiation,allowing consumers to set a flexibility quantity and desired price to trade.A case study with 98 consumers illustrates the proposed market-based non-frequency AS provision approach.Also,three different strategies of consumers’participation are implemented and tested in a real low-voltage distribution network with radial topology.It is shown that consumers can make a profit from the sale of their flexibility while contributing to keeping the network power losses,voltage,and current within pre-defined limits.Ultimately,the results demonstrate the value of AS coming directly from end-users. | Ricardo Faia Fernando Lezama Tiago Pinto Pedro Faria Zita Vale José Manuel Terras Susete Albuquerque | 2023 | Journal of Modern Power Systems and Clean Energy2023,11,3: | 0 |
| 6 | Synthesis and structure of a praseodymium (Ⅲ) complex with carboxylate ligand:A thermal and spectroscopic study显示文摘One Pr(Ⅲ) lanthanide ion complex was initially synthesized and characterized by TGA-DSC in air atmosphere, as well as characterized by CHN elemental analysis, defining the stoichiometric ratio as Pr(DMBz)_3. The gaseous products evolved during the thermal decomposition were also monitored in N_2 atmosphere employing TGA/FT-IR system. A crystal structure is obtained by state-of-the-art powder X-rays diffraction methods measured in conventional laboratory equipment and refined by the Rietveld method, which defined it as a monoclinic system of the space group P2_1/C with a polymeric crystal structure, [Pr(DMB_Z)_3]_n. FT-IR theoretical spectrum and time-dependent density functional theory(TD-DFT) were calculated from TGA-DSC and crystalline system data. The experimental and theoretical FT-IR spectra present a high correlation degree when the main stretching bands are compared, while the energy transfer(HOMO — LUMO) in their neighborhoods suggests the main contributions of the light-emitting states. | Kátia Veronica Tenório José Augusto Teixeira Leandro Moreira de Campos Pinto Flávio Júnior Caires Oswaldo Treu-Filho Fáhio Alencar dos Santos Tiago André Denck Colman Alexandre Cuin Cláudio Teodoro de Carvalho | 2018 | Journal of Rare Earths2018,36,10: | 0 |
| 7 | Sediment geochemistry of the urban Lake Paulo Gorski显示文摘The objective of this study was to evaluate the concentration and distribution of heavy metals in the sediments of Paulo Gorski Lake, as well as the metals' bioavailability and potential ecological risk, and to define the anthropogenic and natural heavy metal contributions to the lake. The chemical elements calcium(Ca), cadmium(Cd), cobalt(Co), chromium(Cr), copper(Cu), iron(Fe), potassium(K), magnesium(Mg), manganese(Mn), sodium(Na), nickel(Ni), lead(Pb), and zinc(Zn) were quantified by flame atomic absorption spectrophotometry with two extraction methods to quantify the bioavailable and nonbioavailable fractions. The data were evaluated using multivariate statistics and sediment quality indices.All sediment collection points(S1, S2, S3, S4 and S5) are different in terms of the concentration of heavy metals, except for S4 and S5, which were statistically equal. The bioavailable fraction of the elements in the sediment follows the sequence Pb > Cu > Mn > Zn > Ni > Cr > phosphorus(P) for all points. The elements Co, Cr, Pb, and Zn showed moderate to considerable contamination at all points. Only points S3 and S5 had moderate ecological risk. Urbanization has been affecting Paulo Gorski Lake via the input of chemical elements, especially Co and Pb. The points most affected by heavy metal contamination are S3 and S5 when the sedimentological sensitivity factor is considered. The lake has high hydrodynamics,causing some of the contaminants that enter the system to leave it, leading to potential negative impacts downstream. | Marcelo Bevilacqua Remor Silvio Cesar Sampaio Sacha de Rijk Marcio Antfnio Vilas Boas Jackeline Tatiane Gotardo Everton Tiago Pinto Fabio Augusto Schardong | 2018 | International Journal of Sediment Research2018,33,4: | 0 |
| 8 | Braamcamp Freire中学,葡萄牙里斯本显示文摘Braamcamp Freire中学位于里斯本庞蒂尼亚历史城区的边缘,占地约17380m^2,毗邻起伏的地势。除了学校北面的山谷,整个校园都是庞蒂尼亚城区的一部分。该校始建于1986年,由五栋标准化预制建筑组成——中间一栋为平层,另外四栋为二层建筑。这些建筑按照东西向排列,通过走廊相互连接。学校设施包括一个体育馆和一个地势较低的户外操场,两者与教学楼都没有连接。 | CVD Barquitectos Cristina Verissimo Diogo Burnay Joo Falco Rodolfo Reis Joana Barrelas Tiago Santos Adam Pelissero Andre Barbosa ngelo Branquinho Ari Nieto Guilherme Bivar Hugo Nascimento Inês Carrapio Irune Ardanza Josè Maria Lavena Leonor Vaz Pinto Luigi Martinelli Miguel Travesso Silvia Amaral Silvia Maggi invisiblegentleman.com 严佳钰 | 2014 | 建筑技艺2014,20,9: | 0 |
| 9 | 最低能耗学校显示文摘项目地点:巴西里约热内卢项目类型:建筑(教育)开工日期:2006年初一个用于学校建筑的小型能源设计项目,包括自然通风装置、能够防御太阳直接辐射的自然照明装置以及屋顶花园。 | Michael Laar Celio Ferreira Filho Diniz Eduardo Franco Azeredo Canellas Eduardo Teixeira Pinto Dezouzart Tiago Macedo Costa Gualda | 2010 | 世界建筑导报2010,,1: | 0 |
| 10 | 79&PARK住宅区显示文摘位于G?rdet国家公园边缘,Kullen有意识地塑造了一个尊重且适应环境的形式,并展现出与众不同的社区和壮丽的景色。为直接回应周围环境,建筑的西北和东南角高起至临近周边的高度;而距离公园最远、且本是视野最不好的东北角被拉高以使其拥有公园和港口最壮阔的景色。建筑西南角延伸至最远处的G?rdet国家公园;为了在建筑和自然之间创造一个人性化的柔和边缘,西南角被尽可能地压低. | H■gni Laksáfoss Agata Wozniczka Agne Tamasauskaite Alberto Herzog Borko Nikolic Christin Svensson Claudio Moretti Dominic Black Eva Seo-Andersen Frederik Wegener Gabrielle Nadeau Jacob Lykkefold Aaen Jaime Peiro Suso Jan Magasanik Jesper Boye Andersen Jonas Aars■Larsen Julian Andres Ocampo Salazar Karl Johan Nyqvist Karol Bogdan Borkowski Katarina Mácková Katrine Juul Kristoffer Negendahl Lucian Racovitan Maria Teresa Fernandez Rojo Max Gabriel Pinto Min Ter Lim Narisara Ladawal Schr■der Romea Muryn Ryohei Koike Sergiu Calacean Song He Taylor McNally-Anderson Terrence Chew Thomas Sebastian Krall Tiago Sá Tobias Vall■S■rensen Tore Banke Laurian Ghinitoiu 朱翰林(译) | 2019 | 城市环境设计2019,0,2: | 0 |