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1A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure显示文摘因为他们的人的白血球抗原(HLA ) haplotype 将强烈增加与房间线的相对更小的队为某些人口匹配的度,同型结合的人的胚胎的干细胞(hESCs ) 被认为是为 hESC 银行的更好的房间来源。同型结合的 hESCs 能从单性生殖的胚胎被产生,但是仅仅异质接合的 hESCs 用当前的策略被建立了没有第二极的身体挤出,人工地激活卵母细胞。这里,我们在 vitro 授精处理从 one-pronuclear 卵母细胞追随者例程报导一根人的同型结合的转换字符线(chHES-32 ) 的第一成功的推导。chHES-32 房间与正常 hESCs 表示普通标记和基因。他们处于一个无差别的状态被宣传超过一年(>P50 ) 了并且维持了 46 的稳定的 karyotype, XX。当在 vivo 并且在 vitro 区分了时, chHES-32 房间能从所有三胚胎的细菌层形成衍生物。五父亲一般地表示的印的基因和他们与卵母细胞施主相同的 HLA 遗传型的几乎无法发现的表示显示了他们的单性生殖的起源。用染色体宽的单个核苷酸的多型性分析并且 DNA 采指纹, chHES-32 房间的 homozygosity 进一步被证实。结果显示“讨厌”的 one-pronuclear 卵母细胞可能是为人的同型结合、单性生殖的转换字符的潜在的来源,并且为从单性生殖的 haploid 卵母细胞获得同型结合的 hESC 线建议了其他的策略。Ge Lin 2007Cell Research2007,17,12:15
2Application of deep eutectic solvents in biomass pretreatment and conversion显示文摘Biomass is renewable, abundant, cheap, biocompatible, and biodegradable materials and has been used to produce chemicals, materials,energy, and fuels. However, most of the biomass, especially most of the biomass polymers are not soluble in common solvents, which hinders their pretreatment and conversion. Deep eutectic solvents(DESs) are environmental-friendly, cheap, and highly tunable, with high solubility,which renders them potential applications in biomass pretreatment and conversion. They could be used as solvents or catalysts and so on. This paper intends to review the application of DESs for the pretreatment of biomass and conversion of biomass to value-added products. We focus on the following topics related to biomass and DESs:(1) DESs for the pretreatment of biomass;(2) DESs for the dissolution and separation of biomass or extraction of chemicals from biomass;(3) DESs for biomass conversion;(4) Drawbacks, and recyclability of DESs for pretreatment and conversion of biomass.Yu Chen Tiancheng Mu 2019Green Energy & Environment2019,4,2:15
3Revisiting greenness of ionic liquids and deep eutectic solvents显示文摘Green solvents are one of the hot topics of green chemistry.Ionic liquids(ILs)and deep eutectic solvents(DESs)are deemed as green solvents to a certain extent,and they have been applied in many areas,such as dissolution,separation,catalysis,electrochemistry and material synthesis.However,the greenness of ILs and DESs should be revisited because more and more evidences have shown that they are not always green.In this perspective,besides the reported merits,the disadvantages and problems of some ILs and DESs,such as instability,volatility,hygroscopicity,toxicity,flammability,regenerability,cost,energy consumption and impurities are discussed.Moreover,13 strategies to avoid the disadvantages of ILs and DESs and to increase the greenness are proposed.Comparison of the greenness of ILs and DESs is further conducted.This perspective provides some new viewpoints on the greenness of ILs and DESs.Yu Chen Tiancheng Mu 2021Green Chemical Engineering2021,2,2:11
4Versatile on-chip light coupling and(de)multiplexing from arbitrary polarizations to controlled waveguide modes using an integrated dielectric metasurface显示文摘Metasurfaces have found broad applicability in free-space optics,while its potential to tailor guided waves remains barely explored.By synergizing the Jones matrix model with generalized Snell’s law under the phase-matching condition,we propose a universal design strategy for versatile on-chip mode-selective coupling with polarization sensitivity,multiple working wavelengths,and high efficiency concurrently.The coupling direction,operation frequency,and excited mode type can be designed at will for arbitrary incident polarizations,outperforming previous technology that only works for specific polarizations and lacks versatile mode controllability.Here,using silicon-nanoantenna-patterned silicon-nitride photonic waveguides,we numerically demonstrate a set of chip-scale optical couplers around 1.55μm,including mode-selective directional couplers with high coupling efficiency over 57%and directivity about 23 d B.Polarization and wavelength demultiplexer scenarios are also proposed with 67%maximum efficiency and an extinction ratio of 20 d B.Moreover,a chip-integrated twisted light generator,coupling free-space linear polarization into an optical vortex carrying 1 h orbital angular momentum(OAM),is also reported to validate the mode-control flexibility.This comprehensive method may motivate compact wavelength/polarization(de)multiplexers,multifunctional mode converters,on-chip OAM generators for photonic integrated circuits,and high-speed optical telecommunications.YUAN MENG ZHOUTIAN LIU ZHENWEI XIE RIDE WANG TIANCHENG QI FUTAI HU HYUNSEOK KIM QIRONG XIAO XING FU QIANG WU SANG-HOON BAE MALI GONG XIAOCONG YUAN 2020Photonics Research2020,8,4:8
5Progress in small-molecule luminescent materials for organic light-emitting diodes显示文摘Organic light-emitting diodes(OLEDs) have been extensively studied since the first efficient device based on small molecular luminescent materials was reported by Tang. Organic electroluminescent material, one of the centerpieces of OLEDs, has been the focus of studies by many material scientists. To obtain high luminosity and to keep material costs low, a few remarkable design concepts have been developed. Aggregation-induced emission(AIE) materials were invented to overcome the common fluorescence-quenching problem, and cross-dipole stacking of fluorescent molecules was shown to be an effective method to get high solid-state luminescence. To exceed the limit of internal quantum efficiency of conventional fluorescent materials, phosphorescent materials were successfully applied in highly efficient electroluminescent devices. Most recently, delayed fluorescent materials via reverse-intersystem crossing(RISC) from triplet to singlet and the 'hot exciton' materials based on hybridized local and charge-transfer(HLCT) states were developed to be a new generation of low-cost luminescent materials as efficient as phosphorescent materials. In terms of the device-fabrication process, solution-processible small molecular luminescent materials possess the advantages of high purity(vs. polymers) and low procession cost(vs. vacuum deposition), which are garnering them increasing attention. Herein, we review the progress of the development of small-molecule luminescent materials with different design concepts and features, and also briefly examine future development tendencies of luminescent materials.Tiancheng Yu Linlin Liu Zengqi Xie Yuguang Ma 2015Science China Chemistry2015,58,6:7
6The electrochemical stability of ionic liquids and deep eutectic solvents显示文摘Room temperature ionic liquids(ILs) composed of cations and anions, as well as deep eutectic solvents(DESs) composed of hydrogen bond donors(HBDs) and hydrogen bond acceptors(HBAs), are regarded as green solvents due to their low volatility. They have been used widely for electrochemically driven reactions because they exhibit high conductivity and excellent electrochemical stability. However, no systematic investigations on the electrochemical potential windows(EPWs), which could be used to characterize the electrochemical stability, have been reported. In this regard, the EPWs of 33 ILs and 23 DESs have been studied utilizing cyclic voltammetry(CV) method and the effects of structural factors(cations and anions of ILs, and HBDs and HBAs of DESs) and external factors(electrode, water content) on the EPWs have been comprehensively investigated. The electrochemical stability of selected ILs comprising five traditional cations, namely imidazolium, pyridinium, pyrrolidinium, piperidinium and ammonium and 13 kinds of versatile anions was studied. The results show that for ILs, both cation and anion play an important role on the reductive and oxidative potential limit. For a same IL at different working electrode, for example, glassy carbon(GC), gold(Au) and platinum(Pt) electrode, the largest potential window is almost observed on the GC working electrode. The investigations on the EPWs of choline chloride(Ch Cl), choline bromide(Ch Br), choline iodide(Ch I), and methyl urea based DESs show that the DES composed of Ch Cl and methyl urea has the largest potential window. This work may aid the selection of ILs or DESs for use as a direct electrolyte or a solvent in electrochemical applications.Qingbo Li Jingyun Jiang Guofeng Li Wancheng Zhao Xinhui Zhao Tiancheng Mu 2016Science China Chemistry2016,59,5:6
7Review:Recent advances in multisensor multitarge11racking using random finite set显示文摘In this study,we provide an overview of recent advances in multisensor multitarget tracking based on the random finite set(RFS)approach.The fusion that plays a fundamental role in multisensor filtering is classified into data-level multitarget measurement fusion and estimate-level multitarget density fusion,which share and fuse local measurements and posterior densities between sensors,respectively.Important properties of each fusion rule including the optimality and sub-optimality are presented.In particulax,two robust multitarget density-averaging approaches,arithmetic-and geometric-average fusion,are addressed in detail for various RFSs.Relevant research topics and remaining challenges are highlighted.Kai DA Tiancheng LI Yongfeng ZHU Hongqi FAN Qiang FU 2021Frontiers of Information Technology & Electronic Engineering2021,22,1:5
8Multi-EAP: Extended EAP for multi-estimate extraction for SMC-PHD filter显示文摘The ability to extract state-estimates for each target of a multi-target posterior, referred to as multi-estimate extraction(MEE), is an essential requirement for a multi-target filter, whose key performance assessments are based on accuracy, computational efficiency and reliability. The probability hypothesis density(PHD) filter, implemented by the sequential Monte Carlo approach,affords a computationally efficient solution to general multi-target filtering for a time-varying number of targets, but leaves no clue for optimal MEE. In this paper, new data association techniques are proposed to distinguish real measurements of targets from clutter, as well as to associate particles with measurements. The MEE problem is then formulated as a family of parallel singleestimate extraction problems, facilitating the use of the classic expected a posteriori(EAP) estimator, namely the multi-EAP(MEAP) estimator. The resulting MEAP estimator is free of iterative clustering computation, computes quickly and yields accurate and reliable estimates. Typical simulation scenarios are employed to demonstrate the superiority of the MEAP estimator over existing methods in terms of faster processing speed and better estimation accuracy.Li Tiancheng Juan M.Corchado Sun Shudong Fan Hongqi 2017Chinese Journal of Aeronautics2017,30,1:4
9Fabrication of Crack-Free Flattened Bamboo and Its Macro-/MicroMorphological and Mechanical Properties显示文摘This work aimed to help the bamboo industry develop methodology for producing imperfection-free bamboo boards that can serve either decorative or structural benefit to consumers seeking to engage with the bioeconomy.Specifically,softened and slotted bamboo tubes were handled by a roller device with nails to render crack-free flattened bamboo board.Softening temperature and time were optimized herein according to findings regarding chemical composition and board mechanical properties.The optimal softening parameters for saturated steam heat treatment is proved to be 160°C for 8 min.The flattened bamboo board possesses an increased bending strength of 101.5 MPa and a decreased bending modulus of 7.7 GPa,being compared with only-softened bamboo.The corresponding changing mechanism is determined in-depth by the micro-morphological and mechanical results based on in-situ SEM and AFM technologies.Under the action of nails and rolling processes,the bamboo texture becomes compact with crushed and fragmented conduit walls.The resulting cell cavity then becomes stretched and compressed,taking on a morphology which allows for the mechanical penalties associated with flattening to be avoided.According to the micro-mechanical results obtained by AFM,compared with unflatten bamboo,the Young’s modulus of the cell membrane in transverse direction(YT)decreases to 1.00 GPa while the corresponding Young’s modulus in radial direction(YR)increases to 7.29 GPa.Zhichao Lou Tiancheng Yuan Qiuyi Wang Xinwu Wu Shouheng Hu Xiaomeng Hao Xianmiao Liu Yanjun Li 2021Journal of Renewable Materials2021,9,5:4
10The Multi-Weight Neuron with Geometry Algorithm and Its Application显示文摘CAO Wenming HE Tiancheng 2008Chinese Journal of Electronics2008,17,2:4
11Monitoring the Amery Ice Shelf front during 2004-2012 using ENVISAT ASAR data显示文摘The Amery Ice Shelf is the largest ice shelf in East Antarctica. It drains continental ice from an area of more than one million square kilometres through a section of coastline that represents approximately 2% of the total circumference of the Antarctic continent. In this study, we used a time series of ENVISAT ASAR images from 2004-2012 and flow lines derived from surface velocity data to monitor the changes in 12 tributaries of the Amery Ice Shelf front. The results show that the Amery Ice Shelf has been expanding and that the rates of expansion differ across the shelf. The highest average annual rate of advance from 2004-2012 was 3.36 m·d-1 and the lowest rate was 1.65 m·d-1 . The rates in 2009 and 2010 were generally lower than those in other years. There was a low correlation between the rate of expansion and the atmospheric temperature recorded at a nearby research station, however the mechanism of the relationship was complex. This study shows that the expansion of the Amery Ice Shelf is slowing down, reflecting a changing trend in climate and ice conditions in East Antarctica.ZHAO Chen CHENG Xiao HUI Fengming KANG Jing LIU Yan WANG Xianwei WANG Fang CHENG Cheng FENG Zhunzhun CI Tianyu ZHAO Tiancheng ZHAI Mengxi 2013Advances in Polar Science2013,24,2:4
12Parathyroid hormone increases alveolar bone homoeostasis during orthodontic tooth movement in rats with periodontitis via crosstalk between STAT3 and β-catenin显示文摘Periodontitis patients are at risk of alveolar bone loss during orthodontic treatment.The aim of this study was to investigate whether intermittent parathyroid hormone(1–34)treatment(iPTH)could reduce alveolar bone loss during orthodontic tooth movement(OTM)in individuals with periodontitis and the underlying mechanism.A rat model of OTM in the context of periodontitis was established and alveolar bone loss was observed.The control,iPTH and iPTH+stattic groups received injections of vehicle,PTH and vehicle,or PTH and the signal transducer and activator of transcription 3(STAT3)inhibitor stattic,respectively.iPTH prevented alveolar bone loss by enhancing osteogenesis and suppressing bone resorption in the alveolar bone during OTM in rats with periodontitis.This effect of iPTH was along with STAT3 activation and reduced by a local injection of stattic.iPTH promoted osteoblastic differentiation and might further regulate the Wnt/β-catenin pathway in a STAT3-dependent manner.The findings of this study suggest that iPTH might reduce alveolar bone loss during OTM in rats with periodontitis through STAT3/β-catenin crosstalk.Cheng Zhang Tiancheng Li Chenchen Zhou Li Huang Yuyu Li Han Wang Peipei Duan Shujuan Zou Li Mei 2020International Journal of Oral Science2020,12,4:4
13Corrosion-Facilitating Local Plastic Deformation for α-Ti in Methanol显示文摘The effect of corrosion process on facilitating local plastic deformation for α-Ti in methanol has been investigated with the micro-multiplicative moire interferometer technique. The size of plastic zone and the plastic strain ahead of loaded notch have been measured. The results show that the anodic dissolution, or corrosion process itself can enhance the plastic zone and the plastic strain ahead of a loaded notch during stress corrosion of α-Ti in methanolHong LU Tiancheng ZHANG and Wuyng CHU(Dept. of Material Physics, University of Science & Technology Beijing, 100083 Beijing, China)Wanxu ZHU Xunqing SHI and Baochen LIU( Dept. of Surface Science & Corrosion Engineering, University of Science & Technology 1998Journal of Materials Science & Technology1998,14,2:3
14Synthesis and properties of a Pr(III) complex with 2-acetyl- benzimidazoledehyde-glycine Schiff-base ligand显示文摘The 2-acetyl-benzimidazoledehyde-gly- cine Schiff-base ligand and the corresponding Pr(III) complex Pr2L3(NO3)3·2CH3OH (L=C11H10N3O2) were synthesized in methanol and characterized by a series of methods, including chemical analysis, elemental analysis, TOF-MS, 1H NMR, UV-, IR-, Raman spectra, thermal analysis, and the three-dimension fluores- cence excitation and emission spectra. The Pr(III) complex exhibits extraordinary water-solubility and the Pr(III) hydroxide appears at pH≥13. The complex also possesses specific fluorescent properties. Thus, at the excitation wavelengths 200.0-280.0 and 260-350 nm the fluorescence bands were observed at 290.0 and 400.0 nm, respectively.WANG Danghui YANG Yixin YANG Yiqin ZHAO Tiancheng WU Xing WANG Shaokang HOU Yao CHEN Weizong 2006Chinese Science Bulletin2006,51,7:3
15On Mineralize-halo-forming Mechanism of Sareke Glutenite-type Copper Deposit in Xinjiang显示文摘1 Introduction Sareke glutenite-type copper deposit is located in the Sarekebayi basin,a sub-basin of southwest margin of the Tuoyun Mesozoic hinterland basin in the northwestern part of the Tarim Basin.The Tuoyun MesozoicYU Wangjie FANG Weixuan Guo Yuqian Wang Lei Li Tiancheng Lu Jia 2017Acta Geologica Sinica(English Edition)2017,91,S1:3
16PLLA-PCys co-electrospun fibers for capture and elution of glutathione S-transferase显示文摘The copolymer poly(L-lactic acid)-b-poly(L-cysteine) (PLA-b-PCys) was co-electrospun with PLGA into ultrafine fibers. The reduced glutathione (GSH) was conjugated to the fiber surfaces via disulfide bonds. The glutathione S-transferase (GST) was captured onto the GSH fibers via specific substrate-enzyme interaction between the bound GSH and GST. The captured GST was eluted with free GSH aqueous solution and lyophilized to get pure GST powders. The results show that the GSH moieties on the fiber surface retain the bioactivity of the free GSH and thus they can bind specifically with GST and the GST in solution is captured onto the fiber surface. In addition, the bound GSH is not as active as free GSH so that the captured GST can be eluted off from the fiber by free GSH aqueous solution. Based on this principle, GST itself or its fused proteins can be separated and purified very easily. The preliminary purification efficiency is 6.5 mg·(gPCys)-1. Further improvements are undertaken.LU TianCheng SUN Jing DONG XiaoQing CHEN XueSi WANG Yu JING XiaBin 2009Science China Chemistry2009,52,12:3
17Reduction of Low-grade Manganese Dioxide Ore Pellets by Biomass Wheat Stalk显示文摘An investigation on reducing low-grade manganese dioxide ore pellets was carried out by using wheat stalk as reductant. The main impact factors of reduction percent such as particle size, biomass/ore ratio, heating rate, nitrogen flow rate, temperature and time in reduction process were discussed. The morphology and component of manganese dioxide ore particle at different stages were also analyzed by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). The results show the increase of the reduction temperature and time, biomass/ore ratio, and the decrease of particle size, heating rate and nitrogen flow rate can significantly enhance reduction efficiency. The reduction kinetic of the manganese ore is controlled by three-dimensional mass diffusion of gaseous reductive volatiles passing from the surface to the core of the ore particles. The activation energy E and frequency factor A were calculated to be 24.15 kJ · mol-1 and 166 min-1 , respectively. Biomass pyrolysis volatiles adsorbed onto the surface of the ore particle leads to serious variation of the microstructures and chemical composition of the manganese ore particles.Honglei ZHANG Guocai ZHU Hong YAN Yuna ZHAO Tiancheng LI Xiujuan FENG 2013Acta Metallurgica Sinica(English Letters)2013,26,2:3
18SOCS3 Attenuates GM-CSF/IFN-γ-Mediated Inflammation During Spontaneous Spinal Cord Regeneration显示文摘SOCS3,a feedback inhibitor of the JAK/STAT signal pathway,negatively regulates axonal regrowth and inflammation in the central nervous system(CNS).Here,we demonstrated a distinct role of SOCS3 in the injured spinal cord of the gecko following tail amputation.Severing the gecko spinal cord did not evoke an inflammatory cascade except for an injury-stimulated elevation of the granulocyte/macrophage colony-stimulating factor(GM-CSF) and interferon gamma(IFN-γ) cytokines.Simultaneously,the expression of SOCS3 was upregulated in microglia,and unexpectedly not in neurons.Enforced expression of SOCS3 was sufficient to suppress the GMCSF/IFN-γ-driven inflammatory responses through its KIR domain by attenuating the activities of JAK1 and JAK2.SOCS3 was also linked to GM-CSF/IFN-y-induced crosstolerance.Transfection of adenovirus overexpressing SOCS3 in the injured cord resulted in a significant decrease of inflammatory cytokines.These results reveal a distinct role of SOCS3 in the regenerating spinal cord,and provide new hints for CNS repair in mammals.Xuejie Zhang Bingqiang He Hui Li Yingjie Wang Yue Zhou Wenjuan Wang Tiancheng Song Nan Du Xingxing Gu Yi Luo Yongjun Wang 2020Neuroscience Bulletin2020,36,7:3
19Operational optimization of a building-level integrated energy system considering additional potential benefits of energy storage显示文摘As a key component of an integrated energy system(IES),energy storage can effectively alleviate the problem of the times between energy production and consumption.Exploiting the benefits of energy storage can improve the competitiveness of multi-energy systems.This paper proposes a method for day-ahead operation optimization of a building-level integrated energy system(BIES)considering additional potential benefits of energy storage.Based on the characteristics of peak-shaving and valley-filling of energy storage,and further consideration of the changes in the system’s load and real-time electricity price,a model of additional potential benefits of energy storage is developed.Aiming at the lowest total operating cost,a bi-level optimal operational model for day-ahead operation of BIES is developed.A case analysis of different dispatch strategies verifies that the addition of the proposed battery scheduling strategy improves economic operation.The results demonstrate that the model can exploit energy storage’s potential,further optimize the power output of BIES and reduce the economic cost.Sai Liu Cheng Zhou Haomin Guo Qingxin Shi Tiancheng E.Song Ian Schomer Yu Liu 2021Protection and Control of Modern Power Systems2021,6,1:3
20Studies on Cataclastic Lithofacies and Copper Metallogenic Regularity for the Glutenite-type Sareke Copper deposit, Xinjiang显示文摘1 Introduction Large-size glutenite-type copper deposit was controlled by the Mesozoic Sarekebayi intracontinental pull-apart basin in Xinjiang.Strata exposed in the study area include the Mesoproterozoic Akesu Group Complex,HAN Wenhua FANG Weixuan ZHANG Guishan Lu jia Wang lei JIA Runxing LI Tiancheng 2017Acta Geologica Sinica(English Edition)2017,91,S1:3
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