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| 1 | Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and a major cause of cancer-related mortality for which liver resection is an important curative-intent treatment option. However, many patients present with advanced disease and with underlying chronic liver disease and/or cirrhosis, limiting the proportion of patients who are surgical candidates. In addition, the development of recurrent or de novo cancers following surgical resection is common. These issues have led investigators to evaluate the benefit of neoadjuvant and adjuvant treatment strategies aimed at improving resectability rates and decreasing recurrence rates. While high-level evidence to guide treatment decision making is lacking, recent advances in locoregional and systemic therapies, including antiviral treatment and immunotherapy, raise the prospect of novel approaches that may improve the outcomes of patients with HCC. In this review, we evaluate the evidence for various neoadjuvant and adjuvant therapies and discuss opportunities for future clinical and translational research. | Clifford Akateh Sylvester M Black Lanla Conteh Eric D Miller Anne Noonan Eric Elliott Timothy M Pawlik Allan Tsung Jordan M Cloyd | 2019 | World Journal of Gastroenterology2019，25，28： | 16 |
| 2 | The Origin and Evolution of Mutations in Acute Myeloid Leukemia显示文摘 | John S. Welch Timothy J. Ley Daniel C. Link Christopher A. Miller David E. Larson Daniel C. Koboldt Lukas D. Wartman Tamara L. Lamprecht Fulu Liu Jun Xia Cyriac Kandoth Robert S. Fulton Michael D. McLellan David J. Dooling John W. Wallis Ken Chen Christop | 2012 | Cell2012，，2： | 3 |
| 3 | Permafrost-associated natural gas hydrate occurrences on the Alaska North Slope显示文摘 | Timothy S. Collett Myung W. Lee Warren F. Agena John J. Miller Kristen A. Lewis Margarita V. Zyrianova Ray Boswell Tanya L. Inks | 2009 | Marine and Petroleum Geology2009，，2： | 2 |
| 4 | The Origin and Evolution of Mutations in Acute Myeloid Leukemia显示文摘 | John S. Welch Timothy J. Ley Daniel C. Link Christopher A. Miller David E. Larson Daniel C. Koboldt Lukas D. Wartman Tamara L. Lamprecht Fulu Liu Jun Xia Cyriac Kandoth Robert S. Fulton Michael D. McLellan David J. Dooling John W. Wallis Ken Chen Christop | 2012 | Cell2012，，2： | 1 |
| 5 | Topical administration of nepafenac inhibits diabetes-induced retinal microvascular disease and underlying abnormalities of retinal metabolism and physiology 显示文摘 | Timothy SK Miller CM Du YP | 2007 | Diabetes2007，56，： | 1 |
| 6 | Microcomputer Control of Switehed Reluctanee Motor显示文摘 | Bimal K Bose Timothy J E Miller Paul M Szczesny | 1986 | IEEE Transactions on Industry Apptieation1986，22，4： | 1 |
| 7 | 'Life Cycle Saving and the Demographic Transition:The Case of Taiwan'显示文摘 | Ronald Lee Andrew Mason Timothy Miller | | 0，，26： | 1 |
| 8 | Osteopontin is a negative regulator of proliferation and differentiation in MC3T3-E1 pre-osteoblastic cells显示文摘 | Weibiao Huang Brian Carlsen George Rudkin Micah Berry Kenji Ishida Dean T Yamaguchi Timothy A Miller | 2004 | Bone2004，，5： | 1 |
| 9 | Prognostic significance of expression of a ras protein with a molecular weight of 21,000 by human breast cancer显示文摘 | Timothy C Willian R Miller D | 1987 | Cancer Res1987，47，： | 1 |
| 10 | Intrinsic GUS-like activities in seed plants显示文摘 | Ching-yeh Hu Paula P. Chee Robert H. Chesney James H. Zhou Paul D. Miller W. Timothy O’Brien | 1990 | Plant Cell Reports1990，，1： | 1 |
| 11 | Integrating process and motor control显示文摘 | Timothy O' hearn John Somde Cerff Sean Miller | 2002 | Industry Applications Magazine IEEE2002，8，4： | 1 |
| 12 | The association between brain volumes, delirium duration, and cognitive outcomes in intensive care unit survivors: The VISIONS cohort magnetic resonance imaging study*显示文摘 | Max L. Gunther Alessandro Morandi Erin Krauskopf Pratik Pandharipande Timothy D. Girard James C. Jackson Jennifer Thompson Ayumi K. Shintani Sunil Geevarghese Russell R. Miller Angelo Canonico Kristen Merkle Christopher J. Cannistraci Baxter P. Rogers J. | 2012 | Critical Care Medicine2012，，7： | 1 |
| 13 | Influence of thrombolytic therapy, with or without intra-aortic balloon counterpulsation, on 12-month survival in the SHOCK trial显示文摘 | John K French Henry A Feldman Susan F Assmann Timothy Sanborn Sebastian T Palmeri David Miller Jean Boland Christopher E Buller Richard Steingart Lynn A Sleeper Judith S Hochman | 2003 | American Heart Journal2003，，： | 1 |
| 14 | Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action显示文摘 | Gerald T. Ankley David C. Bencic Michael S. Breen Timothy W. Collette Rory B. Conolly Nancy D. Denslow Stephen W. Edwards Drew R. Ekman Natalia Garcia-Reyero Kathleen M. Jensen James M. Lazorchak Dalma Martinovi? David H. Miller Edward J. Perkins Edward F | 2009 | Aquatic Toxicology2009，，3： | 1 |
| 15 | Bluntcrerbrovascular injuries:diagnosis and treatment显示文摘 | Preston R Miller MD Timothy C | 2001 | Trauma2001，51，2： | 1 |
| 16 | Detection and Localization of Intraepithelial Neoplasia and Invasive Carcinoma Using Fluorescence-Reflectance Bronchoscopy: An International, Multicenter Clinical Trial显示文摘 | Eric Edell Stephen Lam Harvey Pass York E. Miller Thomas Sutedja Timothy Kennedy Gregory Loewen Robert L. Keith | 2009 | Journal of Thoracic Oncology2009，，1： | 1 |
| 17 | Comparison of acute myocardial infarct size to two-year mortality in patients <65 to those ≥65 years of age显示文摘 | Todd D Miller Timothy F Christian David O Hodge Mona R Hopfenspirger Bernard J Gersh Raymond J Gibbons | 1999 | The American Journal of Cardiology1999，，： | 1 |
| 18 | Understanding the Use of Immediate Intravesical Chemotherapy for Patients with Bladder Cancer显示文摘 | Frank N. Burks Alice B. Liu Ronald S. Suh Timothy G. Schuster Timothy Bradford Don A. Moylan Peter M. Knapp Daniel S. Murtagh Rodney L. Dunn James E. Montie David C. Miller | 2012 | The Journal of Urology2012，，6： | 1 |
| 19 | Yin Yang 1 Plays an Essential Role in Breast Cancer and Negatively Regulates p27显示文摘 | Meimei Wan Weiwei Huang Timothy E. Kute Lance D. Miller Qiang Zhang Heather Hatcher Jingxuan Wang Daniel B. Stovall Gregory B. Russell Paul D. Cao Zhiyong Deng Wei Wang Qingyuan Zhang Ming Lei Suzy V. Torti Steven A. Akman Guangchao Sui | 2012 | The American Journal of Pathology2012，，： | 1 |
| 20 | Early Results after Laparoscopic Gastric Bypass: EEA vs GIA Stapled Gastrojejunal Anastomosis显示文摘 | Timothy R Shope Robert N Cooney Janelle McLeod Cynthia A Miller Randy S Haluck | 2003 | Obesity Surgery2003，，3： | 1 |
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