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| 1 | Hypertension and chronic ethanol consumption: What do we know after a century of study?显示文摘The influences of life habits on the cardiovascularsystem may have important implications for publichealth, as cardiovascular diseases are among the lead-ing causes of shorter life expectancy worldwide. A linkbetween excessive ethyl alcohol(ethanol) consumptionand arterial hypertension was first suggested early lastcentury. Since then, this proposition has received con-siderable attention. Support for the concept of ethanolas a cause of hypertension derives from several epi-demiologic studies demonstrating that in the generalpopulation, increased blood pressure is significantlycorrelated with ethanol consumption. Although thelink between ethanol consumption and hypertension iswell established, the mechanism through which etha-nol increases blood pressure remains elusive. Possiblemechanisms underlying ethanol-induced hypertensionwere proposed based on clinical and experimental ob-servations. These mechanisms include an increase insympathetic nervous system activity, stimulation of therenin-angiotensin-aldosterone system, an increase of intracellular Ca2+ in vascular smooth muscle, increased oxidative stress and endothelial dysfunction. The pres-ent report reviews the relationship between ethanol intake and hypertension and highlights some mecha-nisms underlying this response. These issues are of interest for the public health, as ethanol consumption contributes to blood pressure elevation in the population. | Katia Colombo Marchi Jaqueline Jóice Muniz Carlos Renato Tirapelli | 2014 | World Journal of Cardiology2014，6，5： | 5 |
| 2 | Caspase-3 and Bcl-2 expression in glioblastoma:an immunohistoehemieal study 显示文摘 | Tirapelli L F Bolini P H Tirapelli D P | 2010 | Arq Neuropsiquiatr2010，68，4： | 1 |
| 3 | Hyperhomocy steinemia induced by feeding rats diets rich in DL- homocysteine thiolactone promotes alterations on carotidreactivity independent of arterial structure 显示文摘 | De Andrade CR Tirapelli CR Haddad R | 2009 | Vascul Pharmacol2009，51，4： | 1 |
| 4 | Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K~ channels in ETB-induced relaxation显示文摘 | Tirapelli CR Casolari DA Yogi A | 2005 | Br J Pharmacol2005，146，6： | 1 |
| 5 | Effect of ethanol consumption on blood pressure and rat mesenteric arterial bed,aorta and carotid responsiveness显示文摘 | Tirapelli CR Leone AF | 2007 | Pharm Pharmacol2007，59，7： | 1 |
| 6 | Hypotensive aetion of naturally oeeurring diterpenes : A therapeutic promise for the treatment of hypertension 显示文摘 | Tirapelli C R Ambrosio S R de Oliveira A M | 2010 | Fitoterapia2010，81，7： | 1 |
| 7 | Caspase-3 and Bcl-2 expression in g~ioblastoma: an immunohisto- chemical study 显示文摘 | Tirapelli LF Bolini PH Tirapelli DP | 2010 | Arq Neuropsiquiatr2010，68，4： | 1 |
| 8 | A novel l)ioartive glass-cerumic for treating dentin hypersensitivity显示文摘 | Tirapelli C Panzeri H Soares KG | 2010 | Braz Oral Res2010，24，4： | 1 |
| 9 | Hyperhomocysteinemia induced by feeding rats di ets rich in dl homocysteine thiolactone promotes alter ations on carotid reactivity independent of arterial structure显示文摘 | ANDRADE C R TIRAPELLI C R HADDAD R | 2009 | Vascul Pharmacol2009，51，： | 1 |
| 10 | Apoptosis in glioma cells treated with PDT显示文摘 | Tirapelli LF Morgueti M da Cunha Tirapelli DP | 2011 | Photomed Laser Surg2011，29，5： | 1 |
| 11 | Caspase-3 and Bcl-2 ex- pression in glioblastoma: an immunohistochemical study 显示文摘 | Tirapelli LF Bolini PH Tirapelli DP | 2010 | Arq Neuropsiquiatr2010，68，4： | 1 |
| 12 | Functional characterization and expression of endothelin receptors in rat carotid artery:involvement of nitric oxide, a vasodilator prostanoid and the opening of K^+ channels in ETB-induced relaxation 显示文摘 | Tirapelli CR Casolari DA Yogi A | 2005 | Br J Pharmacol2005，146，6： | 1 |
| 13 | Biochemical evalua- tion of focal non-reperfusion cerebral ischemia by middle cerebral artery occlusion in rats 显示文摘 | Colli B O Tirapelli D P Carlotti C G | 2008 | Arq Neuropsiquiatr2008，66，3： | 1 |
| 14 | Chronic ethanol consumption reduces adrenomedullin-induced relaxation in the isolated rat aorta显示文摘 | Ulisses V. Hipólito Juliana T. Rocha Alisson Martins-Oliveira Daniela P.C. Tirapelli Ana Jacob-Ferreira Marcelo E. Batalh?o José E. Tanus-Santos Evelin C. Carnio Thiago M. Cunha Regina H. Queiroz Carlos R. Tirapelli | 2011 | Alcohol2011，，8： | 1 |
| 15 | A novel bioactive glass - ceramic for treating dentin hypersensitivity 显示文摘 | Tirapelli C Panzeri H Soares RG et at | 2010 | Braz Oral Res2010，24，4： | 1 |
| 16 | A novel bioactive glass-ce- ramic for treating dentin hypersensitivity显示文摘 | Tirapelli C Panzeri H Soares RG | 2010 | Braz Oral Res2010，24，4： | 1 |
| 17 | Enzymatic pathways involved in the generation of en- dothelin-1 (1-31) from exogenous big enclothelin-1 in the rabbit aorta显示文摘 | Tirapelli CR Fecteau MH Honore JC | 2006 | Br J Pharmacol2006，148，4： | 1 |
| 18 | Effect of chronic ethanol consumption on endothelin-1 generation and conversion of exogenous big-endothelin-1 by the rat carotid artery显示文摘 | Carlos R. Tirapelli Débora A. Casolari Alvaro Yogi Rita C. Tostes Eurode Legros Vera L. Lanchote Sérgio A. Uyemura Ana M. de Oliveira | 2007 | Alcohol2007，，2： | 1 |
| 19 | A novel bioactive glass-ceramic for treating dentin hypersensitivity显示文摘 | Tirapelli C Panzeri H Soares RG | | 0，，04： | 1 |
| 20 | A novel bioactive glassceramic for treating dentin hypersensitivity显示文摘 | Tirapelli C Panzeri H Soares RG | 2010 | Braz Oral Res2010，24，4： | 1 |
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