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| 1 | Expression of cyclooxygenase-2 is associated with p53 accumulation in premalignant and malignant gallbladder lesions显示文摘瞄准:在胆囊癌和它的先锋损害在表示和 p53 累积上检验在 cyclooxygenase-2 (COX-2 ) 之间的关系。方法:包括正常胆量 blader 上皮,发育异常(11 低档 dyplasia 和 16 高级发育异常) 的 27 个盒子和 27 腺癌的 14 个盒子的 68 件胆囊织物样品被免疫组织化学为 COX-2 表示和 p53 累积评估。在 COX-2 表示, p53 累积和 clinicopathological 特征之中的关系被分析。结果:COX-2 被表示在 14.3% 正常胆囊上皮, 70.3% 发育异常的 epite hlium,和 59.2% 腺癌。当划分了成低档和高级发育异常时, COX-2 在 5 是积极的(45.4%) 低档的盒子并且 14 (87.5%) 高级发育异常(P = 0.019 ) 。p53 的累积在 5 被检测(31.2%) 癌的高级发育异常并且在 13 的盒子(48.1%) 。没有 p53 累积在正常上皮或低档发育异常被发现。在表示上的 COX-2 在 18 中的 17 个被观察(94.4%) 有从没有 p53 累积的 50 个盒子的与 20 比较的 p53 累积(40.0%) 的盒子(P <
0.001 ) 。结论:在在正常上皮,低档发育异常和高级发育异常之中的 COX-2 表示的有效差量建议在 COX-2 的表示上,酶是在胆囊 carcinogenensis 的一个早事件。自从有 COX-2 表示的 p53 相互关联的累积,而且,在表示上的 COX-2 在高级发育异常和癌可能是的胆囊观察了部分由于 p53 的机能障碍。 | Mateja Legan Bo(s|ˇ)tjan Luzar Vera Ferlan Marolt Andrej C(o|¨)r | 2006 | World Journal of Gastroenterology2006，12，21： | 7 |
| 2 | An analytical study of offset piston and crankshaft designs and the effect of oil film on piston slap excitation in a diesel engine显示文摘 | HADDAD S D TJAN K T | 1995 | Mech Mach Theory1995，30，2： | 1 |
| 3 | The perception of a face is no more than the sum of its parts显示文摘 | Gold J M Mundy P J Tjan B S | 2012 | Psychol Sci2012，23，4： | 1 |
| 4 | Corrosion inhibition by tungstate in aqueous solutions and its application to coalwater slurries显示文摘 | Sastri V S Tjan C Roberge P R | 1991 | British Corrosion Journal1991，，4： | 1 |
| 5 | The role of HER2/neu overexpression/amplification in the progression of ductal carcinoma in situ to invasive carcinoma of the breast显示文摘 | LATTA E K TJAN S PARKES R K | 2002 | Mod Pathol2002，15，12： | 1 |
| 6 | The role of HER - 2/neu overexpression/amplification in the progression of ductal carcinotua in situ to invasive carcinoma of the breast显示文摘 | Latta EK Tjan S Parkes PK | 2002 | Mod Pathol2002，15，12： | 1 |
| 7 | E--cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in sire of the breast显示文摘 | Mastracd TL Tjan S Bane AL | 2005 | Mod Pathol2005，18，6： | 1 |
| 8 | Influence of ionic strength on aqueous oxidation of SO2 catalyzed by manganese显示文摘 | Janja Tur(s)i(c) Irena Grgi(c) Bo(s)tjan Podkraj(s)ek | 2003 | Atmospheric Environment2003，37，19： | 1 |
| 9 | The role of HER-2/neu overexpression/amplification in the progression of ductal carcinoma in situ to invasive carcinoma of the breast显示文摘 | Latta EK Tjan S Parkes RK | 2002 | Mod Pathol2002，15，12： | 1 |
| 10 | E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast显示文摘 | Mastracci TL Tjan S Bane AL | 2005 | Mod Pathol2005，18，6： | 1 |
| 11 | The role of HER-2/neu overexpression/amplification in the progression of ductal carcinoma in situ to invasive carcinoma of the breast显示文摘 | Latta EK Tjan S Parkes PK | 2002 | Mod Pathol2002，15，12： | 1 |
| 12 | Down-regulation of microRNAs of the miR-200 family and miR-205,and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition显示文摘 | Zidar N Bo(s)tjan (c) i (c) E Gale N | | 0，，04： | 1 |
| 13 | The role of HER2/neu over- expression/amplification in the progression of ductal carcinoma in situ to invasive carcinoma of the breast 显示文摘 | Latta EK Tjan S Parkes RK | 2002 | Mod Pathol2002，15，： | 1 |
| 14 | An analytical study of offset piston and crankshaft designs and the effect of oil film on piston slap excitation in diesel engine显示文摘 | Haddad S D Tjan K T | | 0，，02： | 1 |
| 15 | The role of HER2/neu overexpression/amplification in the progression of ductal carcinoma in situ to invasive carcinoma of the breast显示文摘 | Latta EK Tjan S Parkes RK | 2002 | Mod Pathol2002，15，12： | 1 |
| 16 | Human efficiencyfor recognizing 3-D objects in luminance noise显示文摘 | Tjan B S Braje WL Legge G E Kersten D | 1995 | Vision Re-search1995，35，21： | 1 |
| 17 | E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast显示文摘 | Mastracci T L Tjan S Bane A L | 2005 | Modern Pathology2005，18，6： | 1 |
| 18 | Minimally-invasive versus conventional aortic valve replacement-perioperative course and midterm results显示文摘 | Stypmann J Tjan TD | 1999 | Eur J Cardiothorac Surg1999，16，6： | 1 |
| 19 | Microstructural characterization of alloys of the quasibinary Cu-NiBe system显示文摘 | Savo S Bo(s)tjan M | 2003 | Zeitschrift fur metallkunde2003，94，： | 1 |
| 20 | The role of HER2/neu overexpression/amplification in the progression of ductal carcinoma in situ to invasive carcinoma of the breast显示文摘 | LATTA E K TJAN S PARKES R K | | 0，，12： | 1 |
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