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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Efficacy and tolerability of cancer pain management with controlled-release oxycodone tablets in opioid-naive cancer pain patients,stariing with Smg table显示文摘 | Koizumi W Toma H Watanabe K | 2004 | Jpn J Clin Oncol2004，34，10： | 1 |
| 3 | A QoS-Aware Selection Model for Se- mantic Web Services 显示文摘 | Xia W Tomas V Mick K | 2006 | Computer Science2006，4294，： | 1 |
| 4 | Rosiglitazone,an ag- onist of peroxisome proliferator-activated receptor gamma, protects against gastric ischemia-reperfusion damage in rats:role of oxygen free radicals generation显示文摘 | Villegas l Martin A R Toma W | 2004 | Eur J Phar- macol2004，505，： | 1 |
| 5 | Sub150℃processed meso-superstructured perovskite solar cells with enhanced efficiency显示文摘 | KONRAD W MICHAEL S TOMAS L | 2014 | Energy&Environmental Science2014，7，3： | 1 |
| 6 | Efficacy and tolerability of cancer pain management with controlled-release oxycodone tablets in opioid-naive cancer pain patients,starting with 5 mg tablets显示文摘 | Koizumi W Toma H Watanabe K | 2004 | Jpn J Clin 0ncol2004，34，： | 1 |
| 7 | Polo-like kinase2, a Novel ADAM17 Signaling Component, Regulates Tumor, Necerosis Factor a Ectodomain Shedding显示文摘 | Jeanette S Olga W Tomas K | 2014 | J Biol Chem2014，289，5： | 1 |
| 8 | Effect of pitavastatin on preventing ischemic complications with carotid artery stenting:a multicenter prospective Study-EPOCH-CAS study显示文摘 | Takayama K Taki W Toma N | 2014 | Cardiovasc Intervent Radiol2014，37，6： | 1 |
| 9 | Flavanones, chalcones and dihydrochalcones-nature, occurrence and dietary burden显示文摘 | Tomas W Barberan F A CliffordM N | 2000 | J Sci Food Agric2000，80，： | 1 |
| 10 | Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists 显示文摘 | NAWROCKI A R RAJALA M W TOMAS E | 2006 | J Biol Chem2006，281，15： | 1 |
| 11 | Toll like receptors linking innate and adaptive immune response显示文摘 | Dirk W Tomas W J | 2003 | Veterinary Immunology and Immunopathology2003，91，： | 1 |
| 12 | Minimally invasive direct coronary artery bypass graft: intermediate-term results显示文摘 | Vassiliades Jr Edwin W | 2000 | Ann Thorac Sury2000，70，： | 1 |
| 13 | Drilling of deep micro-hole by EDM显示文摘 | MASUZAWA T MOBER W TOMAS B | 1989 | Annals of the CIRP1989，38，1： | 1 |
| 14 | Stability of multishell fullerenes显示文摘 | Toma'nek D Krastev W Z E | 1993 | Physical Reviewb1993，48，15： | 1 |
| 15 | The Oxidation Behavior of Sprayed MCrAlY Coatings显示文摘 | Brandl W Grabke H J Toma D | 1996 | SurCoat Technol1996，8687，： | 1 |
| 16 | Flavanones, Chalcones and Dihydrochalcones-nature, Occurrence and Dietary Burden显示文摘 | Tomas W Barberan F A Clifford M N | 2000 | J Sci Food Agric2000，80，： | 1 |
| 17 | The characteristics of alumina scales formed on HVOF-sprayed MCrAlY coatings 显示文摘 | Brandl W Toma D Grabke H J | 1998 | Surface and Coatings Technology1998，，109： | 1 |
| 18 | Efficacy and tolerability of cancer pain management with controlled-release oxycodone tablets in opioid naive cancer pain patients,starting with 5 mg tablets显示文摘 | Koizumi W Toma H Watanabe K eta l | 2004 | Jpn J Clin Oncol2004，34，3： | 1 |
| 19 | Studies on the transient stage of oxidation of VPS and HVOF sprayed MCrAlY coatings显示文摘 | Toma D Brandl W Koster U | 1999 | Surface and Coatings Technology1999，，120121： | 1 |
| 20 | Microwave Enhanced Thermal De- contamination of Soil 显示文摘 | ZDZLSLA W W TOMAS Z Z | 1998 | Environmental Science and Technology1998，32，17： | 1 |
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