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| 1 | Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy显示文摘AIM: To evaluate the association between serum concentrations of S100β in patients with cirrhosis and the presence of low grade hepatic encephalopathy(HE).METHODS: This was a cross-sectional study. The population was categorized into four groups healthy subjects, cirrhosis without HE, cirrhosis with covert hepatic encephalopathy(CHE) and cirrhosis with overt HE. Kruskal-Wallis, Mann Whitney's U with Bonferroni adjustment Spearman correlations and area under the ROC were used as appropriate.RESULTS: A total of 61 subjects were included, 46 cirrhotic patients and 15 healthy volunteers. S100β values were different among all groups, and differences remained significant between groups 1 and 2(P < 0.001), and also between groups 2 and 3(P = 0.016), but not between groups 3 and 4. In cirrhotic patients with HE S100β was higher than in patients without HE [0.18(0.14-0.28) ng/m L vs 0.11(0.06-0.14) ng/m L, P < 0.001]. There was a close correlation between serum concentrations of S100β and psychometric hepatic encephalopathy score in patients with cirrhosis without HE compared to the patients with cirrhosis with CHE(r =-0.413, P = 0.019). ROC curve analysis yielded > 0.13 ng/m L as the best cutoff value of S100β for the diagnosis of HE(sensitivity 83.3%, specificity 63.6%).CONCLUSION: Serum concentrations of S100β are higher in patients with cirrhosis than in healthy volunteers, and are further increased in the presence of hepatic encephalopathy. The results suggest that serum biomarkers such as S100β could help in the correct characterization of incipient stages of HE. | Andrés Duarte-Rojo Astrid Ruiz-Margáin Ricardo U Macias-Rodriguez Francisco Javier Cubero José Estradas-Trujillo Rosa Ma Munoz-Fuentes Aldo Torre | 2016 | World Journal of Gastroenterology2016，22，17： | 4 |
| 2 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 3 | Selective oxidation of CO in hydrogen over gold supported on manganese oxides显示文摘 | Rosa M Torres S Atsushi U | 1997 | J Catal1997，168，1： | 1 |
| 4 | Vaseularized retinal pigment epithelial detachment in age-related macular degeneration: treatment and RPE tear incidence 显示文摘 | Introini U Torres Gimeno A Scotti F | 2012 | Graefes Arch Clin Exp Ophthalmol2012，250，9： | 1 |
| 5 | Leaf isozymes as genetic markers in Citrus显示文摘 | TORRES A M SOOST R K DIEDENHOFEN U | 1978 | American Journal of Botany1978，65，8： | 1 |
| 6 | Monozygotic twins are discordant for chronic periodontitis: clinical and bacteriological findings显示文摘 | Torres de Heens GL Loos BG van der Velden U | 2010 | J Clin Periodontol2010，37，2： | 1 |
| 7 | From amorphous to microcrystalline silicon films prepared by hydrogen dilution using the VHF (70 MHz) GD technique 显示文摘 | KROLL U MEIER J TORRES P | 1998 | Non-Cryst Solids1998，230，20： | 1 |
| 8 | Nosocomial pneumonia显示文摘 | Ostendorf U Ewig S Torres A | 2006 | Curr Opin Infect Dis2006，29，4： | 1 |
| 9 | From Amorphous to MicrocrystaUine Silicon Films Prepared by Hydrogen Dilution Using the VHF (70 MHz) GD Technique 显示文摘 | Kroll U Meier J Torres P | 1998 | Journal of Non-Crystalline Solids1998，227，： | 1 |
| 10 | MRI findings in an infant with vaccine associated paralytic poliomyelitis 显示文摘 | Ferraz-Filho JR dos Santos Torres U de Oliveira EP | 2010 | Pediatr Radio12010，40，1： | 1 |
| 11 | Suc- cessful autologous stem cell transplantation in two patients with juvenile dermatomyositis显示文摘 | Holzer U van Royen Kerkhof A van der Torre P | 2010 | Scand J Rheumatol2010，39，1： | 1 |
| 12 | Microcrystalline/Micromorph Silicon Thin-film Solar Cells Prepared by VHF-GD Technique 显示文摘 | Meier J Vallat-Sauvain E Dubail S Kroll U Dubail J Golay S Feitknecht L Torres P Fay S Fischer D Shah A | 2001 | Solar Energy Materials & Solar Cells2001，66，： | 1 |
| 13 | Press-coated tablets for time-programmed release of drugs 显示文摘 | Conte U Maggi L Torre ML | 1993 | Biomaterials1993，14，13： | 1 |
| 14 | 查看详情显示文摘 | Meier J Vallat-Sauvain E Dubail S Kroll U Dubail J Golay S Feitknecht L Torres P Fa(y) S Fischer D Shah A | | 0，，： | 1 |
| 15 | Leaf isozymes as genetic marker in Citrus显示文摘 | Torres A M Soost R K Diedenhofen U | 1978 | Amer J Bot1978，65，： | 1 |
| 16 | Press- coated tablets for time- programmed release of drugs显示文摘 | Conte U Maggi L Torre M | 1993 | Biomaterials1993，14，13： | 1 |
| 17 | Successful autologous stem cell transplantation in two patients with juvenile dermatomyositis显示文摘 | Holzer U van Royen-Kerkhof A van der Torre P | | 0，，01： | 1 |
| 18 | Influence of ceria loading on the NOx storage and reduction performance of model Pt-Ba/A1203 NSR catalyst显示文摘 | Pereda-Ayo B De La Torre U Gonzilez-Marcos M P | 2015 | Catalysis Today2015，241，： | 1 |
| 19 | Orientation, Simplicity and Inclusion Test for Planar Polygons显示文摘 | Feito F Torres J C U rena A | 1995 | Computers&Graphics1995，19，4： | 1 |
| 20 | How bricks-and-mortar attributes affect online banking adoption显示文摘 | Carlos Flavián Miguel Guinalíu Eduardo Torres | 2006 | International Journal of Bank Marketing2006，，6： | 1 |
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