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| 1 | Contemporary surgical management of rectovaginal fistula in Crohn's disease显示文摘Rectovaginal fistula is a disastrous complication of Crohn's disease(CD) that is exceedingly difficult to treat. It is a disabling condition that negatively impacts a women's quality of life. Successful management is possible only after accurate and complete assessment of the entire gastrointestinal tract has been performed. Current treatment algorithms range from observation to medical management to the need for surgical intervention. A wide variety of success rates have been reported for all management options. The choice of surgical repair methods depends on various fistula and patient characteristics. Before treatment is undertaken, establishing reasonable goals and expectations of therapy is essential for both the patient and surgeon. This article aims to highlight the various surgical techniques and their outcomes for repair of CD associated rectovaginal fistula. | Michael A Valente Tracy L Hull | 2014 | World Journal of Gastrointestinal Pathophysiology2014,5,4: | 2 |
| 2 | 2015年全球新药研发报告——第二部分:趋势复杂,亮点频现(Ⅴ)显示文摘概述并精辟解析2015年全球制药行业发生的重大事件,包括药品定价、孤儿药研发、美国FDA优先审评凭证制度、药品研发管线缩减以及正在持续运作的并购。并展望未来,预测2016年有望上市的新药。 | Graul A I Cruces E Dulsat C Tracy M | 2016 | 药学进展2016,40,8: | 2 |
| 3 | Protein synthesis in salivery glands of drosophila melanngaster: relation to chromosome puffs显示文摘 | Tissieres A Mitchell HK Tracy UM | 1974 | J Mol Biol1974,84,: | 2 |
| 4 | Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair显示文摘AIM To determine endothelin-1(ET-1)concentration before and after surgical coarctectomy and evaluate its association with left ventricular geometric change.METHODSA prospective,cohort study of 24 patients aged 2 d to 10years with coarctation of the aorta undergoing surgical repair.A sub-cohort of patients with age<1 mo was classified as'neonates'.Echocardiograms were performed just prior to surgery and in the immediate post-op period to assess left ventricle mass index and relative wall thickness(RWT).Plasma ET-1 levels were assessed at both time points.Association between ET-1 levels and ventricular remodeling was assessed.RESULTSPatients<1 year demonstrated higher pre-op ET-1 than post-op(2.8 pg/m L vs 1.9 pg/m L,P=0.02).Conversely,patients>1 year had no change in ET-1 concentration before and after surgery(1.1 vs 1.4,NS).Pre-op,patients<1 year demonstrated significantly higher ET-1 than older children(2.8 vs 1.1,P=0.001).Post-op there was no difference between the age groups(1.9 vs 1.4,NS).Neither RWT nor left ventricle mass index(LVMI)varied from pre-op to post-op.The subset of neonates showed a strong positive correlation between pre-op ET-1 and RWT(r=0.92,P=0.001).Patients with ET-1>2 pg/m L preop demonstrated higher LVMI(65.7 g/m^(2.7) vs 38.5 g/m^(2.7),P=0.004)and a trend towards higher RWT(45%vs39%,P=0.07)prior to repair than those with lower ET-1concentration.CONCLUSIONET-1 concentration is significantly variable in the perioperative period surrounding coarctectomy.Older children and infants have different responses to surgical repair suggesting different mechanisms of activation. | Benjamin Steven Frank Tracy T Urban Suhong Tong Courtney Cassidy Max B Mitchell Christopher S Nichols Jesse A Davidson | 2017 | World Journal of Cardiology2017,9,12: | 2 |
| 5 | Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes; the insulin resistance atherosclerosis study显示文摘 | Festa A DAgostino R Jr Tracy RP | 2002 | Diabetes2002,51,4: | 1 |
| 6 | Elevated C - reactive protein values and at herosclerosis in sudden coronary death association with different pat hologies 显示文摘 | BURKE A P TRACY R P MALCOM G T | 2001 | Circulation2001,105,: | 1 |
| 7 | Identifying and assessing ecotourism visitor impacts at eight protected areas in Costa Rica and Belize显示文摘 | Tracy A Farrell Jeffrey L Marion | 2001 | Environment Conservation2001,28,3: | 1 |
| 8 | Elevated level of acute phaso proteinsan plasminogen activator inhibitor predict the development of type 2 diabetes 显示文摘 | Festa A Agostino R Tracy RP | 2002 | Diabetes2002,51,4: | 1 |
| 9 | Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial 显示文摘 | Tracy A Glauser B John M | 2002 | Epilepsia2002,43,5: | 1 |
| 10 | Elevated C-reactive protein values and atherosclersis in sudden coronarydeath:association with different pathologies显示文摘 | BURKE A P TRACY R P KOLODGIE F | 2002 | Circulation2002,105,17: | 1 |
| 11 | Application of ultra- high moulus composites to primary structures 显示文摘 | Foster J L Tracy J J Elizondo C A | 1993 | AIAA-93-1405 -CP1993,,: | 1 |
| 12 | Symbol sequence statistics in noisy chaotic signal reconstruction显示文摘 | Tang X Z Tracy E R Boozer A D | 1995 | Physical Review E1995,51,5: | 1 |
| 13 | Z01Z ACCP/AFIA/ HRS Focused Update of the 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities A Report of the Ameri- can College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines显示文摘 | Tracy C M Epstein A E Darbar D | 2012 | Circulation2012,126,14: | 1 |
| 14 | Parental socialization of emotion显示文摘 | Eisenberg N Cumberland A Tracy L | | 0,,04: | 1 |
| 15 | Angiotensin II type 1 receptor polymorphisms in the cardiovascular haelth study: relation to blood pressure, ethnicity, and cardiovascular events显示文摘 | HINDORFF L A HECKBERT S R TRACY R | 2002 | Am J Hypertens2002,15,: | 1 |
| 16 | Preparation of monodisperse silica particales: Control of size and mass fraction显示文摘 | Bogush G H Tracy M A Zukoskin C F | 1988 | J Non-Cryst Solids1988,104,: | 1 |
| 17 | Elevated level of acute phase proteinsan plasminogen activator inhibitor predict the development of type 2diabetes显示文摘 | Festa A Agostino R Tracy RP | 2002 | Diabetes2002,51,4: | 1 |
| 18 | Elevated levels of acute phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes:the insulin resistance atherosclerosis study显示文摘 | Festa A D' Agostino R Jr Tracy RP | 2002 | Diabetes2002,51,4: | 1 |
| 19 | Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness显示文摘 | Kohen R Dobra A Tracy JH | 2014 | Transl Psychiatry2014,4,4: | 1 |
| 20 | Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs 显示文摘 | Tissieres A Mttchell H K Tracy U M | 1974 | Journal of Molecular Biology1974,84,3: | 1 |