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| 1 | High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis显示文摘AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(ESCC)screening program in China.METHODS:A decision analytic Markov model of ESCC was developed.Separate model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in China.Hypothetical 50-year-old individuals were followed until age 80 or death.We compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an HRME.Model parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer database.Health states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and death.Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations.Costs in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price Index.RESULTS:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY gained.Standard endoscopic screening was weakly dominated.Among the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per QALY.For both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per QALY.One-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s iodine(>40%)and lower specificity of HRME(<70%)could make Lugol’s iodine screening cost-effective.For the high-risk population,the results of the model were not substantially affected by varying the follow-up rate after Lugol’s iodine screening,Lugol’s iodine test characteristics(sensitivity and specificity),or HRME specificity.CONCLUSION:The incorporation of HRME into an ESCC screening program could be cost-effective in China.Larger studies of HRME performance are needed to confirm these findings. | Chin Hur Sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu Alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum Sharmila Anandasabapathy | 2015 | World Journal of Gastroenterology2015，21，18： | 8 |
| 2 | A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA显示文摘 | Marcella Cesana Davide Cacchiarelli Ivano Legnini Tiziana Santini Olga Sthandier Mauro Chinappi Anna Tramontano Irene Bozzoni | 2011 | Cell2011，，4： | 4 |
| 3 | 亚急性脑卒中的前庭功能康复显示文摘前庭康复是一个日益增长的新兴领域,但是,很少有随机对照试验研究这方面的结果。本研究初步调查了前庭运动对亚急性卒中患者的有效性。将25例卒中导致单侧偏瘫患者随机分为两组,其中12例为对照组(CG),13例为前庭康复组(VR)。且这些患者符合额外的入选标准,即能够在没有辅助装置的情况下独立行走。 | 李建华 Tramontano M. | 2019 | 中国康复2019，34，1： | 3 |
| 4 | Total synthesis of the quinonoid alcohol dehydrogenase eoenzyme (1) of methylotrophic bacteria显示文摘 | COREY E J TRAMONTANO A | 1981 | J Am CHem Soc1981，103，： | 1 |
| 5 | Obserbations on the regulation of thyroid cell groeth显示文摘 | Inghar SH Tramontano D Amebesi-lmpiombato S | 1988 | Horm Metab Res1988，17，： | 1 |
| 6 | 6--2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro显示文摘 | TRAMONTANO E ESPOSITO F BADAS R | 2005 | Antiviral Res2005，65，2： | 1 |
| 7 | Insulin -like growth factor-Ⅰ stimulates the growth of rat thyroid cells in culture and synergizes the stimulation of DNA synthesis induced by TSH and Graves1g-G显示文摘 | Tramontano D Cushing GW Moses AC | 1986 | Endocrinology1986，119，2： | 1 |
| 8 | Retroperitoneal tumors Observations of 8 cases 显示文摘 | TRAMONTANO R PONZIO S FRACCALINI M | 1998 | Minerva Chir1998，58，6： | 1 |
| 9 | Insulin-like growth factor-I stimulates the growth of rat thyroid cells in culture and synergizes the stimulation of DNA synthesis induced by TSH and Graves'-lgG显示文摘 | Tramontano D Cushing GW Moses AC | 1986 | Endocrinology1986，119，2： | 1 |
| 10 | Chiral trialkylborane reducing agents:Preparation of 1-deuterio primary alcohols of high enantiomeric purity显示文摘 | MIDLAND M M GREER S TRAMONTANO A | 1979 | J Am Chem Soc1979，101，6： | 1 |
| 11 | Antibody modeling:Implications for engineering and design显示文摘 | LESK AM Tramontano A | 2000 | Methods2000，20，： | 1 |
| 12 | Conformations of the third hypervariable region in the VH domain of immunoglobulins显示文摘 | MOREA V TRAMONTANO A RUSTICI M | 1998 | J Mol Biol1998，275，： | 1 |
| 13 | Intraoperative neurophy-siological monitoring during surgery for Chiari malformations 显示文摘 | Sala F Squintani G Tramontano V | 2011 | Neurol Sei2011，32，3： | 1 |
| 14 | Circulating endothelial microparticles in diabetes mellitus 显示文摘 | Tramontano A F R Lyubarova J Tsiakos | 2010 | Mediators Inflamm2010，2010，25： | 1 |
| 15 | Crosslinking of waterborne polyurethane dispersions 显示文摘 | Tramontano Werner J | 1995 | Journal of Coatings Technology1995，67，848： | 1 |
| 16 | Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway 显示文摘 | Tramontano AF Muniyappa R Black AD | 2003 | Biochem Biophys Res Commun2003，308，4： | 1 |
| 17 | Crosslinking of waterborne polyurethane dispersions 显示文摘 | TRAMONTANO V J BLANK W J | 1995 | Journal of Coating Technology1995，67，848： | 1 |
| 18 | Properties of crosslinked polyurethane dispersions显示文摘 | Blank WJ Tramontano VJ | 1996 | Prog Org Coat1996，，27： | 1 |
| 19 | Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway 显示文摘 | TRAMONTANO A F MUNIYAPPA R BLACK A D | 2003 | Biochem Biophys Res Commun2003，308，： | 1 |
| 20 | A survey of trigonelline concentrations in dry seeds of the Dicotyledoneae 显示文摘 | Tramontano W A McGinley P A Ciancaglini E F | 1986 | Environ Exp Bot1986，26，3： | 1 |
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