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| 1 | Outcomes of robotic vs laparoscopic hepatectomy:A systematic review and meta-analysis显示文摘AIM: To perform a systematic review and metaanalysis on robotic-assisted vs laparoscopic liver resections.METHODS: A systematic literature search was performed using Pub Med, Scopus and the Cochrane Library Central. Participants of any age and sex, who underwent robotic or laparoscopic liver resection were considered following these criteria:(1) studies comparing robotic and laparoscopic liver resection;(2) studies reporting at least one perioperative outcome; and(3) if more than one study was reported by the same institute, only the most recent was included. The primary outcome measures were set for estimated blood loss, operative time, conversion rate, R1 resection rate, morbidity and mortality rates, hospital stay and major hepatectomy rates.RESULTS: A total of 7 articles, published between 2010 and 2014, fulfilled the selection criteria. The laparoscopic approach was associated with a significant reduction in blood loss and lower operative time(MD = 83.96, 95%CI: 10.51-157.41, P = 0.03; MD = 68.43, 95%CI: 39.22-97.65, P < 0.00001, respectively). No differences were found with respect to conversion rate, R1 resection rate, morbidity and hospital stay.CONCLUSION: Laparoscopic liver resection resulted in reduced blood loss and shorter surgical times compared to robotic liver resections. There was no difference in conversion rate, R1 resection rate, morbidity and length of postoperative stay. | Roberto Montalti Giammauro Berardi Alberto Patriti Marco Vivarelli Roberto Ivan Troisi | 2015 | World Journal of Gastroenterology2015，21，27： | 22 |
| 2 | International consensus statement on robotic hepatectomy surgery in 2018显示文摘The robotic surgical system has been applied in liver surgery. However,controversies concerns exist regarding a variety of factors including the safety,feasibility, efficacy, and cost-effectiveness of robotic surgery. To promote the development of robotic hepatectomy, this study aimed to evaluate the current status of robotic hepatectomy and provide sixty experts' consensus and recommendations to promote its development. Based on the World Health Organization Handbook for Guideline Development, a Consensus Steering Group and a Consensus Development Group were established to determine the topics, prepare evidence-based documents, and generate recommendations. The GRADE Grid method and Delphi vote were used to formulate the recommendations. A total of 22 topics were prepared analyzed and widely discussed during the 4 meetings. Based on the published articles and expert panel opinion, 7 recommendations were generated by the GRADE method using an evidence-based method, which focused on the safety, feasibility, indication,techniques and cost-effectiveness of hepatectomy. Given that the current evidences were low to very low as evaluated by the GRADE method, further randomized-controlled trials are needed in the future to validate these recommendations. | Rong Liu Go Wakabayashi Hong-Jin Kim Gi-Hong Choi Anusak Yiengpruksawan Yuman Fong Jin He Ugo Boggi Roberto I Troisi Mikhail Efanov Daniel Azoulay Fabrizio Panaro Patrick Pessaux Xiao-Ying Wang Ji-Ye Zhu Shao-Geng Zhang Chuan-Dong Sun Zheng Wu Kai-Shan Tao Ke-Hu Yang Jia Fan Xiao-Ping Chen | 2019 | World Journal of Gastroenterology2019，25，12： | 23 |
| 3 | Perioperative thromboprophylaxis in liver transplant patients显示文摘Improvements in surgical and anesthetic procedures have increased patient survival after liver transplantation(LT). However, the perioperative period of LT can still be affected by several complications. Among these, thromboembolic complications(intracardiac thrombosis, pulmonary embolism, hepatic artery and portal vein thrombosis) are relatively common causes of increased morbidity and mortality. The benefit of thromboprophylaxis in general surgical patients has already been established, but it is not the standard of care in LT recipients. LT is associated with a high bleeding risk, as it is performed in a setting of already unstable hemostasis. For this reason, the role of routine perioperative prophylactic anticoagulation is usually restricted. However, recent data have shown that the bleeding tendency of cirrhotic patients is not an expression of an acquired bleeding disorder but rather of coexisting factors(portal hypertension, hypervolemia and infections). Furthermore, in cirrhotic patients, the new paradigm of ‘‘rebalanced hemostasis' ' can easily tip towards hypercoagulability because of the recently described enhanced thrombin generation, procoagulant changes in fibrin structure and platelet hyperreactivity. This new coagulation balance, along with improvements in surgical techniques and critical support, has led to a dramatic reduction in transfusion requirements, and the intraoperative thromboembolic-favoring factors(venous stasis, vessels clamping, surgical injury) have increased the awareness of thrombotic complications and led clinicians to reconsider the limited use of anticoagulants or antiplatelets in the postoperative period of LT. | Lesley De Pietri Roberto Montalti Daniele Nicolini Roberto Ivan Troisi Federico Moccheggiani Marco Vivarelli | 2018 | World Journal of Gastroenterology2018，24，27： | 9 |
| 4 | Artificial intelligence in the diagnosis and management of colorectal cancer liver metastases显示文摘Colorectal cancer(CRC)is the third most common malignancy worldwide,with approximately 50%of patients developing colorectal cancer liver metastasis(CRLM)during the follow-up period.Management of CRLM is best achieved via a multidisciplinary approach and the diagnostic and therapeutic decision-making process is complex.In order to optimize patients’survival and quality of life,there are several unsolved challenges which must be overcome.These primarily include a timely diagnosis and the identification of reliable prognostic factors.Furthermore,to allow optimal treatment options,a precision-medicine,personalized approach is required.The widespread digitalization of healthcare generates a vast amount of data and together with accessible high-performance computing,artificial intelligence(AI)technologies can be applied.By increasing diagnostic accuracy,reducing timings and costs,the application of AI could help mitigate the current shortcomings in CRLM management.In this review we explore the available evidence of the possible role of AI in all phases of the CRLM natural history.Radiomics analysis and convolutional neural networks(CNN)which combine computed tomography(CT)images with clinical data have been developed to predict CRLM development in CRC patients.AI models have also proven themselves to perform similarly or better than expert radiologists in detecting CRLM on CT and magnetic resonance scans or identifying them from the noninvasive analysis of patients’exhaled air.The application of AI and machine learning(ML)in diagnosing CRLM has also been extended to histopathological examination in order to rapidly and accurately identify CRLM tissue and its different histopathological growth patterns.ML and CNN have shown good accuracy in predicting response to chemotherapy,early local tumor progression after ablation treatment,and patient survival after surgical treatment or chemotherapy.Despite the initial enthusiasm and the accumulating evidence,AI technologies’role in healthcare and CRLM management is not yet fully established.Its limitations mainly concern safety and the lack of regulation and ethical considerations.AI is unlikely to fully replace any human role but could be actively integrated to facilitate physicians in their everyday practice.Moving towards a personalized and evidence-based patient approach and management,further larger,prospective and rigorous studies evaluating AI technologies in patients at risk or affected by CRLM are needed. | Gianluca Rompianesi Francesca Pegoraro Carlo DL Ceresa Roberto Montalti Roberto Ivan Troisi | 2022 | World Journal of Gastroenterology2022，28，1： | 5 |
| 5 | Quality of life after liver transplantation:State of the art显示文摘Quality of life(QoL) after deceased donor liver transplantation is increasingly recognized as a major outcome parameter. We reviewed recent publications in this rapidly evolving field in order to summarize recent achievements in the field and to define opportunities and perspectives for research and improvement of patient care. QoL does improve after liver transplantation according to a typical pattern. During the first year, there is a significant improvement in QoL. After one year, the improvement does stabilise and tends to decline slightly. In addition to the physical condition, different psychological parameters(such as depression, anxiety, sexual function) and sociodemographic elements(professional state, sex, marital state) seem to impact QoL. Opportunities for further research are the use of dedicated questionnaires and identification of influencing factors for QoL. | Louis Onghena Wouter Develtere Carine Poppe Anja Geerts Roberto Troisi Aude Vanlander Frederik Berrevoet Xavier Rogiers Hans Van Vlierberghe Xavier Verhelst | 2016 | World Journal of Hepatology2016，8，18： | 3 |
| 6 | Modulation of Portal Graft Inflow: A Necessity in Adult Living-Donor Liver Transplantation?显示文摘 | Roberto Troisi Guy Cammu Giuseppe Militerno Luc De Baerdemaeker Johan Decruyenaere Eric Hoste Peter Smeets Isabelle Colle Hans Van Vlierberghe Mirko Petrovic Dirk Voet Eric Mortier Uwe J. Hesse Bernard de Hemptinne | 2003 | Annals of Surgery2003，，3： | 2 |
| 7 | Early cerebral hemodynamic changes during passive movements and motor recovery after stroke显示文摘 | Matteis M Vernieri F Troisi E | 2003 | J Neurol2003，250，7： | 2 |
| 8 | Laparoscopic liver resection of benign liver tumors显示文摘 | B. Descottes D. Glineur F. Lachachi D. Valleix J. Paineau A. Hamy M. Morino H. Bismuth D. Castaing E. Savier P. Honore O. Detry M. Legrand J.S. Azagra M. Goergen M. Ceuterick J. Marescaux D. Mutter B. Hemptinne R. Troisi J. Weerts B. Dallemagne C. Jehaes | 2003 | Surgical Endoscopy2003，，4： | 2 |
| 9 | Menopausal estrogen and estrogen- progestin replacement therapy and breast cancer risk 显示文摘 | Lubin J Troisi R ET AL | 2000 | JAMA2000，283，4： | 1 |
| 10 | Maternal serum oestrogen and androgen concentrations in preeclamptic and uncomplicated pregnancies显示文摘 | Troisi R Potischman N Roberts JM | 2003 | Int J Epidemiol2003，32，3： | 1 |
| 11 | Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program 显示文摘 | MIRABELLO L TROISI R J SAVAGE S A | 2009 | Cancer2009，115，7： | 1 |
| 12 | TranscranialDopp ler as sessment of cerebrovascular reactivity in symp tomatic and asymp to matic severe carotid stenosis显示文摘 | Silvestrini M Troisi E Cup ini LM | 1996 | Stroke1996，27，： | 1 |
| 13 | Transplanted liver: consequences of denervation for liver functions显示文摘 | Colle I Van VH Troisi R | 2004 | Anat Rec A Discov Mol Cell Evol Biol2004，280，1： | 1 |
| 14 | Surgical treatment of visceral artery aneurysms: A 25-year experience显示文摘 | Raffaele Pulli Walter Dorigo Nicola Troisi Giovanni Pratesi Alessandro Alessi Innocenti Carlo Pratesi | 2008 | Journal of Vascular Surgery2008，，2： | 1 |
| 15 | Liver Transplantation Using Non-Heart-Beating Donors: Belgian Experience显示文摘 | D. Monbaliu F. Van Gelder R. Troisi B. de Hemptinne J. Lerut R. Reding J. de Ville de Goyet O. Detry A. De Roover P. Honore V. Donckier M. Gelin D. Ysebaert R. Aerts W. Coosemans J. Pirenne | 2007 | Transplantation Proceedings2007，，5： | 1 |
| 16 | Enhanced-MRI and ultrasound evaluation of painful shoulder in patients after stroke: a pilot study显示文摘 | Pompa A Clemenzi A Troisi E | 2011 | Eur Neurol2011，66，3： | 1 |
| 17 | Hepato-venous reconstruction in orthotopic liver transplantation with preservation of the recipients' inferior vena cava and veno-venous bypass显示文摘 | U J Hesse F Berrevoet R Troisi E | 2000 | Langenbeck''s Archives of Surgery2000，385，5： | 1 |
| 18 | Osteosarcoma incidence and survival rates from 1973 to 2004 :data from the Surveillance, Epide- miology, and End Results Program 显示文摘 | Mirabello L Troisi R J Savage SA | 2009 | Cancer2009，115，7： | 1 |
| 19 | Early Arterial Revascularization After Hepatic Artery Thrombosis May Avoid Graft Loss and Improve Outcomes in Adult Liver Transplantation显示文摘 | A. Scarinci M. Sainz-Barriga F. Berrevoet B. van den Bossche I. Colle A. Geerts X. Rogiers H. van Vlierberghe B. de Hemptinne R. Troisi | 2010 | Transplantation Proceedings2010，，10： | 1 |
| 20 | TranscranialDoppler assessment of cerebrovascular reactivity in symp-tomatic and asymptomatic severe carotid stenosis 显示文摘 | Silvestrini M Troisi E Cupini LM | 1996 | Stroke1996，，27： | 1 |
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