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    题名 作者 年代 出处 被引量
1Structural transition of silicene on Ag(111)显示文摘Ryuichi Arafune Chun-Liang Lin Kazuaki Kawahara Noriyuki Tsukahara Emi Minamitani Yousoo Kim Noriaki Takagi Maki Kawai 2013Surface Science2013,,:3
2Effect of soaking and gaseous treatment on GABA content in germinated brown rice显示文摘Noriko Komatsuzaki Kikuichi Tsukahara Hidechika Toyoshima Tadanao Suzuki Naoto Shimizu Toshinori Kimura 2005Journal of Food Engineering2005,,2:2
3Simultaneous augmentation of muscle and bone by locomomimetism through calcium-PGC-1αsignaling显示文摘Impaired locomotion has been extensively studied worldwide because those afflicted with it have a potential risk of becoming bedridden.Physical exercise at times can be an effective remedy for frailty,but exercise therapy cannot be applied in all clinical cases.Medication is safer than exercise,but there are no drugs that reinforce both muscle and bone when administered alone.Multiple medications increase the risk of adverse events;thus,there is a need for individual drugs targeting both tissues.To this end,we established a novel sequential drug screening system and identified an aminoindazole derivative,locamidazole(LAMZ),which promotes both myogenesis and osteoblastogenesis while suppressing osteoclastogenesis.Administration of this drug enhanced locomotor function,with muscle and bone significantly strengthened.Mechanistically,LAMZ induced Mef2c and PGC-1αin a calcium signaling–dependent manner.As this signaling is activated upon physical exercise,LAMZ mimics physical exercise.Thus,LAMZ is a promising therapeutic drug for locomotor diseases,including sarcopenia and osteoporosis.Takehito Ono Ryosuke Denda Yuta Tsukahara Takashi Nakamura Kazuo Okamoto Hiroshi Takayanagi Tomoki Nakashima 2022Bone Research2022,10,4:2
4The characteristics of aromatase deficient hairless mice indicate important roles of extragonadal estrogen in the skin显示文摘 Kakuo S Moriwaki S 2008J Steroid Biochem Mol Biol2008,108,12:1
5Stent placement for atherosclerotic stenosis of the vertebral artery ostium:Angiographic and clinical outcomes in 117 consecutive patients显示文摘Hatano T Tsukahara T Miyakoshi A 2011Neurosurgery2011,68,1:1
6Near-inffared spectroscopic sensing system for on-line milk quality assessment in a milking robot显示文摘Masataka Kawasaki Shuso Kawamura Maki Tsukahara 2008Computers and Electronics in Agrieulatre2008,63,1:1
7A C-Band 4 Stage Low Noise Miniaturized Amplifier Using Lumped Elements显示文摘Tsukahara Y Chaki S Sasaki Y 1995IEEE MTT-S Digest1995,,:1
8Effects of antioxidants and nitric oxide on TNF-alpha-induced adhesion molecule expression and NF-kappaB activation in human dermal microvascular endothelial cells显示文摘Jiang MZ Tsukahara H Ohshima Y et a l 2004Life Sci2004,75,10:1
9Sustaining hypercitrullinemia,hypercholesterolemia and augmented oxidative stress in Japanese children with aspartate/glutamate carrier isoform 2-citrin-deficiency even during the silent period显示文摘Nagasaka H Okano Y Tsukahara H 0,,01:1
10Vasoactive and natriuretic mediators in umbilical cord Mood: a report of our observation and review of the literature显示文摘Tsukahara H Sekine K Miura M 2002Early Hum Dev2002,69,12:1
11Impact of Ultrasound Attenuation and Plaque Rupture as Detected by Intravascular Ultrasound on the Incidence of No-Reflow Phenomenon After Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction显示文摘Mitsuaki Endo Kiyoshi Hibi Tomoaki Shimizu Naohiro Komura Ikuyoshi Kusama Fumiyuki Otsuka Takayuki Mitsuhashi Noriaki Iwahashi Jun Okuda Kengo Tsukahara Masami Kosuge Toshiaki Ebina Satoshi Umemura Kazuo Kimura 2010JACC: Cardiovascular Interventions2010,,5:1
12Elevated expression of DNA topoisomerase Ⅱ in camprothecin - resistant human tumor cell lines 显示文摘Sugimoto Y Tsukahara S OH Hara T 1990Cancer Res1990,50,24:1
13Multiobjective genetic algorithm applied to aerodynamic design of cascade airfoils显示文摘Obayashi S Tsukahara T Nakamura T 2000IEEE Transactions on Industrial Electronics2000,47,1:1
14Vanadium-based solid solution alloys with three-dimensional network structure for high capacity metal hydride electrodes显示文摘Tsukahara M Takahashi K Mishima T 1997Journal of Alloys and Compounds1997,253,:1
15Stenting for stenoses of the proximal vertebral artery显示文摘Hatano T Tsukahara T Araki K 1999Interv Neuroradiol1999,5,2:1
16An Improved Thn ighput Method for the Measurement of Outgassing Rates of Materials 显示文摘Yang Y Saitoh K Tsukahara S 1995Vacuum1995,46,12:1
17Discovery of potent and orally active 3- alkoxy-5-phenoxy-N-thiazolyl benza- mides as novel allosteric glucokinase activators 显示文摘Lino T Tsukahara D Kamata K 2009Bioorg Med Chem2009,17,7:1
18Evaluation of endogenous nitric oxide synthesis in congenital urea cycle enzyme defects 显示文摘Nagasaka H Tsukahara H Yorifuji T 2009Metabolism2009,58,3:1
19Surface Modification of Titanium Using EDM Process 显示文摘TSUKAHARA H MINAMI H MASUI K 1999Journal of the Japan Society of Electrical Machining Engineers1999,33,74:1
20Moyamoya disease With repeat-ed intraventricular hemorrhage due to aneurysm rupture Report of two cases显示文摘Hamada J Hashimoto N Tsukahara T 0,,:1
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