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| 1 | Inflammatory bowel disease in an underdeveloped region of Northeastern Brazil显示文摘AIM: To evaluate the demographic characteristics and clinical phenotypes of inflammatory bowel disease(IBD) in a geographic area in Northeastern Brazil.METHODS: This retrospective study was conducted at the Hospital of the Federal University of Piauí in Northeastern Brazil. Demographic characteristics and clinical phenotypes of IBD were analyzed in relation to the time of diagnostic confirmation, which was defined as the date of disease onset. Data were collected between January 2011 and December 2012 and included all census patients 18 years of age or older during that period for whom there was diagnostic confirmation of Crohn's disease(CD), ulcerative colitis(UC), or unclassified colitis according to the Montreal criteria. We also analyzed the period of time between the onset of clinical manifestations and the diagnosis of IBD(delay in the diagnosis). Statistical analyses included means and standard deviations for numeric variables and the Pearson χ2 adherence test for nominal variables. The annual index occurrence and overall prevalence of IBD at our institution were also calculated, with P values < 0.05 indicating statistical significance. This study was approved by the Institutional Ethics and Research Committee.RESULTS: A total of 252 patients with IBD were included, including 152(60.3%) UC patients and 100(39.7%) CD patients. The clinical and demographic characteristics of all patients with IBD showed a female to male ratio of 1.3:1.0 and a mean age of35.2(SD = 14.5) years. In addition, the majority of patients were miscegenated(171, 67.9%), had received higher education(157, 62.4%), lived in urban areas(217, 86.1%), and were under the age of 40 years(97, 62.5%). For patients with CD, according to the Montreal classification, the predominant features present from the onset of disease were an age between 17 and 40 years(A2); colonic disease location(L2); and nonstricturing, nonfistulizing disease behavior(B1). However, approximately one-quarter of all CD patients demonstrated perineal involvement. We also observed considerable delay in the diagnosis of IBD throughout the entire study period(mean = 35.5 mo). In addition, the annual index occurrence rose from 0.08 to 1.53 cases/105 inhabitants/year during the study period, and the prevalence rate was 12.8 cases/105 inhabitants in 2012. Over the last two decades, there was a noted increase in the frequency of IBD in the study area.CONCLUSION: In this study, there was a predominance of patients with UC, young people under 40 years of age, individuals with racial miscegenation, and low annual incomes. | José Miguel Luz Parente Claudio Saddy Rodrigues Coy Viriato Campelo Mírian Perpétua Palha Dias Parente Leonardo Araújo Costa Renata Mendes da Silva Celso Stephan José Murilo Robilotta Zeitune | 2015 | World Journal of Gastroenterology2015，21，4： | 3 |
| 2 | Detecting anomalies in beams and plate based on Hilbert - Huang transform of real signal 显示文摘 | Quek S T Tua P S Wang Q | 2003 | Smart Material and Structures2003，12，： | 1 |
| 3 | Difficulties in diffusion of tacit knowledge in organizations显示文摘 | Tua Haldin-Herrgard | 2000 | Journal of Intellectual Capital2000，1，4： | 1 |
| 4 | Design of visual eryptographic methods with smooth looking decoded images of invariant size for grey-level images 显示文摘 | TUA S F HOUB Y C | 2007 | Imaging Science Journal2007，55，2： | 1 |
| 5 | Detection of cracks in plates using piezo-actuated Lamb waves 显示文摘 | TUA P S QUEK S T WANG Q | 2004 | Smart Materials & Structures2004，13，4： | 1 |
| 6 | Detecting anomaliesin beams and plate based on the Hilbert-Huang transform of real signals 显示文摘 | Quek S T Tua P S Wang Q | 2003 | Smart Materials and Structures2003，12，3： | 1 |
| 7 | Antioxidant Activity of Water Extract of Harng Jyur( Chrysanthemum morifolium Ramat) 显示文摘 | Duha P D Tua Y Y Yenb G C | 1999 | Food Science and Technology1999，32，5： | 1 |
| 8 | Difficulties in diffusion of tacit knowledge in organizations显示文摘 | Tua Haldin-Herrgard | 2000 | Journal of Intellectual Capital2000，，4： | 1 |
| 9 | Detecting anomalies in beams and plate based on the Hilbert-Huang transform of real signals 显示文摘 | Quek S T Tua P S Wang Q | 2003 | Smart Materials and Structures2003，12，3： | 1 |
| 10 | ACE inhibition by astilbin isolated from Erythroxylum gonocladum (Mart.) O.E. Schulz显示文摘 | M.D. Lucas-Filho G.C. Silva S.F. Cortes T.R. Mares-Guia V. Perpétua Ferraz C.P. Serra F.C. Braga | 2009 | Phytomedicine2009，，5： | 1 |
| 11 | Vacuolating megalencephalic leukoencephalopathy with mild clinical course validated by diffusion tensor imaging and MR spectroscopy显示文摘 | Tua YF Chen CY Huang CC | 2004 | Am J Neuroradiol2004，25，6： | 1 |
| 12 | Detection of cracks in cyllindrical pipes and plates using piezo-actuated Lamb 'waves 显示文摘 | Tua P S Quek S T Wang Q | 2005 | Smart Materials & Structures2005，14，6： | 1 |
| 13 | Detecting anomalies in beams and plate based on the Hilbert-Huang transform of real signals显示文摘 | Quek S T Tua P S Wang Q | 2003 | Smart Materials and Structures2003，12，： | 1 |
| 14 | Difficulties in diffusion of tacit knowledge in organizations 显示文摘 | Tua Haldin- Herrgard | 2000 | Journal of Intellectual Capital2000，1，4： | 1 |
| 15 | Detecting anomalies in beams and plate based on the Hilbert - Huang transform of real signals显示文摘 | Quek S T Tua P S Wang Q | 2003 | Smart Materials and Structures2003，12，： | 1 |
| 16 | Radiosynthesis and biological evaluation of a promising sigma(2)-receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET/SPECT probe for imaging breast cancer显示文摘 | Zhude Tua Jinbin Xua Lynne A Jones | 2010 | Applied Radiation and Isotopes2010，68，： | 1 |
| 17 | Tracking the natural history of infantile with diuretic显示文摘 | O Tua LA Treves ST Peters CA | 1992 | J Nucl Med1992，33，12： | 1 |
| 18 | Difficulties in diffusion of tacit knowledge in organizations显示文摘 | Tua Haldin-Herrgard | 2000 | Intellectual Capital2000，，4： | 1 |
| 19 | Detection of cracks in cylindrical pipes and plates using piezo-actuated Lamb waves显示文摘 | Tua P S Quek S T Wang Q | | 0，，06： | 1 |
| 20 | Hemostasis and cancer: tumor cells induce the expression of tissue factor-like procoagulant activity on endothelial cells显示文摘 | Maiolo A Tua A Grignani G | 2002 | Haematologica2002，87，6： | 1 |
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