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| 1 | 短期胰岛素泵强化治疗期间2型糖尿病患者胰岛功能变化对预后的影响显示文摘目的 对2型糖尿病(T2DM)患者短期胰岛素泵强化治疗期间胰岛β细胞功能的变化趋势作初步探索性研究,观察治疗期间β细胞功能受抑制的程度是否与治疗后β细胞功能的改善程度相关.方法 选取2013年1月15日至3月20日在中山大学附属第一医院内分泌科住院的36例T2DM患者为研究对象,所有患者接受9~13d的胰岛素泵强化治疗,观察治疗前、中、后空腹C肽(FCP)和精氨酸刺激后C肽水平的变化趋势,使用Pearson或Spearman法分析治疗期间FCP下降幅度(△FCP%)和精氨酸刺激后C肽增加值(CPi=C肽峰值-FCP)的下降幅度(△CPi%)与血糖、治疗后C肽水平的相关性.使用多重线性回归法分析治疗后C肽水平与年龄、体质指数(BMI)、血糖及△FCP%等的相关性.结果 强化治疗后受试者空腹血糖(FPG)较治疗前下降[(6.6±1.5)比(13.6±3.7) mmol/L,t=9.374,P<0.05],FCP治疗后较治疗前明显升高[(0.71±0.30)比(0.62±0.29) pmol/L,t=2.854,P<0.05].和治疗前、后相比,治疗期间FCP显著下降[分别为(0.25±0.20)比(0.62±0.29) pmol/L,t=-9.153,P<0.05; (0.25±0.20)比(0.71±0.30) pmol/L,t=-11.021,均P<0.05];CPi较治疗前、后明显下降[分别为(0.37±0.30)比(0.58 ±0.41) pmol/L,t=-6.201;(0.37±0.30)比(0.52±0.30) pmol/L,t=-4.856,均P<0.05].多重线性回归分析中,校正年龄、血糖、病程、BMI以及肌酐清除率后,△FCP%与△CPi%与治疗后CPi水平独立相关(标化β系数:-0.329、-0.334,均P<0.05).结论 短期胰岛素泵强化治疗T2DM患者能明显改善β细胞功能,治疗期间β细胞分泌功能受到抑制,治疗后可即刻恢复;治疗期间β细胞功能受抑制的幅度与治疗后β细胞功能改善程度相关. | 刘娟 Jasmeen Tuladhar 柯伟健 邓婉萍 刘建彬 曹筱佩 李延兵 | 2014 | 中华糖尿病杂志2014，6，5： | 16 |
| 2 | Properties of a New Dental Photocurable Resin based on the Expanding Monomer and Threecomponent Photoinitiator System显示文摘The purpose of this study was to use a three-component photoinitiation system comprising 1wt% CQ(camphorquinone), 2wt% DMAEMA(2-(dimethylamino) ethyl meth acrylate) and 2wt% Ph2I+PF6-(diphenyliodonium hexafluorophosphate) to initiate the copolymerization of the matrix resins which combine bisphenol-S-bis(3-methacrylate-2-hydroxy propyl) ether(BisS-GMA) with the expanding monomer unsaturated spiro orthoesters 2-methylene-1,4,6-trispiro[4,4] nonane(MTOSN), for minimizing the volumetric shrinkage that generally occurs during polymerization. It was hypothesized that MTOSN would expand volumetrically during polymerization under the three-component photoinitiator system and further reductions in volumetric shrinkage would be obtained. The performance study which consists of degree of conversion and condition of the ring-opening reactions of MTOSN, volumetric shrinkage and mechanical properties including tensile bond strength, compressive strength and Vicker's hardness were carried out respectively by Fourier transfer infrared, the dilatometer and the universal testing machine. The results supported that the dental composites based on the expanding monomer and three-component photoinitiator system engendered a greater decrease of volumetric shrinkage and better mechanical properties. | 付静 LIU Wenjia LIU Xiaoqing Sapna laxmi tuladhar WAN Qianbing 王航 | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，2： | 3 |
| 3 | 镜下边缘增强缝线桥全层修复肩袖分层撕裂显示文摘[目的]介绍关节镜下边缘增强缝线桥全层修复肩袖分层撕裂的手术技术与初步临床疗效。[方法] 2017年8月~2019年04月对21例肩袖分层撕裂患者进行镜下修复。镜下探明肩袖撕裂的部位,并进行清创,磨钻打磨肱骨大结节,直至磨平、松质骨渗血为止。复位分层肩袖,应用单排固定或内排打结固定加强缝合固定肩袖撕裂两端的止点,全层修复分层撕裂,于足印区缝线桥压紧固定整体肩袖。[结果]所有患者均顺利手术,无感染等并发症。随访时间至少12个月,UCLA评分由术前的(13.86±1.77)分提高到最终随访时的(32.62±1.53)分,Constant-Murley评分由术前(35.05±4.25)分提高到(92.67±3.86)分(P<0.001)。[结论]镜下边缘增强缝线桥全层修复能很好地恢复分层肩袖的整体性和完整性,防治肩袖进一步撕裂,增强肩袖整体的初始强度,改善患者关节功能。 | 张立智 胡孙君 杜守超 Rujan Tuladhar 卫禛 熊文峰 张世民 | 2021 | 中国矫形外科杂志2021，29，10： | 3 |
| 4 | Modularion of 5- HT4- receptor function in the rat isolated ileum by fluoxetine : the involve- ment of endogenous 5-hydroxytryptamine 显示文摘 | TULADHAR BR GOSTALL B NAYLOR RJ | 2002 | Br J Pharmacol2002，136，1： | 1 |
| 5 | Control of parallel inverters indistributed AC power systems with conside- ration of line Transactions on Industry 131-138 Guerrero J M, de Vicuna impedance design of impedanceeffect显示文摘 | Tuladhar A Jin H Unger T | 2000 | IEEE Electronics2000，36，1： | 1 |
| 6 | Control of parallel inverters in distributed AC power systems with consideration of line impedance effect显示文摘 | Tuladhar A Jin H Unger T | 2000 | IEEE Transactions on Industry Applications2000，36，1： | 1 |
| 7 | Control of parallel inverters in distributed AC power systems with consideration of line impedance effect显示文摘 | Tuladhar A Hua J Unger T | 2000 | Industry Applications IEEE Transactions on2000，36，1： | 1 |
| 8 | Measuring organizational flexibility:an exploration and general model显示文摘 | Phillips F Tuladhar S D | 2000 | Technologieal Forecasting and Social Change2000，64，： | 1 |
| 9 | A top-down bottom-up modeling approach to climate change policy analysis 显示文摘 | Tuladhar S D Yuan M Bernstein P | 2009 | Energy Economics2009，31，： | 1 |
| 10 | Spinal dural arteriovenous fistula: diagnosed late 显示文摘 | Wilbers J Meijer FJ Tuladhar A | 2013 | Ned Tijdschr Geneeskd2013，157，12： | 1 |
| 11 | Role of co-stimulation in leishmaniasis 显示文摘 | Tuladhar R Natarajan G Satoskar AR | 2011 | Int J Biol Sci2011，7，9： | 1 |
| 12 | Residual viral and bacterial contamination of surfaces after cleaning and disinfec- tion显示文摘 | Tuladhar E Hazeleger WC Koopmans M | 2012 | Appl Environ Microbiol2012，78，21： | 1 |
| 13 | Measuring Organizational Flexibility: An Exploration and General Model显示文摘 | | 2000 | Technological Forecasting and Social change 642000，2338，： | 1 |
| 14 | Control of parallel inverters in distributed AC power systems with consideration of line impedance effect显示文摘 | Anil Tuladhar Hua Jin Tom Unger | 2000 | IEEE Trans on Industry applications2000，36，1： | 1 |
| 15 | Measuring organizationnal flexibility: an exploration and general model显示文摘 | FRED PHILLIPS SUGANDHA D TULADHAR | 2000 | Technological Forecasting and Social Change2000，，164： | 1 |
| 16 | Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease显示文摘 | de Laat K F Tuladhar A M van Norden A G | | 0，，1： | 1 |
| 17 | Measuring organizational flexibility: an exploration and general model显示文摘 | PHILLIPS F TULADHAR S D | 2000 | Technologi- cal Forecasting and Social Change2000，64，1： | 1 |
| 18 | Control of parallel inverters in distributed AC power systems with consideration of line impedance effect显示文摘 | TULADHAR A JIN H UNGER T | 2000 | IEEE Trans on Industrial Applications2000，12，36： | 1 |
| 19 | Modulation of 5-HT4 receptor function in the rat isolated ileum by fluoxetine: The involvement of endogenous 5-hydroxytryptamine显示文摘 | Tuladhar BR Costall B Naylor RJ | 2002 | Br J Pharmacol2002，136，： | 1 |
| 20 | Spinal dural arteriovenous fistula: frequently diagnosed late显示文摘 | Wilbers J Meijer FJ Tuladhar A | 2013 | Ned Tijdschr Ge- neeskd2013，157，12： | 1 |
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