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| 1 | All ileo-cecal ulcers are not Crohn's:Changing perspectives of symptomatic ileocecal ulcers显示文摘AIM To investigated clinical,endoscopic and histopathological parameters of the patients presenting with ileocecal ulcers on colonoscopy.METHODS Consecutive symptomatic patients undergoing colonoscopy,and diagnosed to have ulcerations in the ileocecal(I/C) region,were enrolled.Biopsy was obtained and theirclinical presentation and outcome were recorded.RESULTS Out of 1632 colonoscopies,104 patients had ulcerations in the I/C region and were included in the study.Their median age was 44.5 years and 59% were males.The predominant presentation was lower GI bleed(55,53%),pain abdomen ± diarrhea(36,35%),fever(32,31%),and diarrhea alone(9,9%).On colonoscopy,terminal ileum was entered in 96(92%) cases.The distribution of ulcers was as follows:Ileum alone 40%(38/96),cecum alone 33%(32/96),and both ileum plus cecum 27%(26/96).The ulcers were multiple in 98% and in 34% there were additional ulcers elsewhere in colon.Based on clinical presentation and investigations,the etiology of ulcers was classified into infective causes(43%) and noninfective causes(57%).Fourteen patients(13%) were diagnosed to have Crohn's disease(CD).CONCLUSION Non-specific ileocecal ulcers are most common ulcers seen in ileo-cecal region.And if all infections are clubbed together then infection is the most common(> 40%) cause of ulcerations of the I/C region.Cecal involvement and fever are important clues to infective cause.On the contrary CD account for only 13% cases as a cause of ileo-cecalulcers.So all symptomatic patients with I/C ulcers on colonoscopy are not Crohn's. | Jay Toshniwal Romesh Chawlani Amit Thawrani Rajesh Sharma Anil Arora Hardik L Kotecha Mohan Goyal Vijendra Kirnake Pankaj Jain Pankaj Tyagi Naresh Bansal Munish Sachdeva Piyush Ranjan Mandhir Kumar Praveen Sharma Vikas Singla Rinkesh Bansal Vineet Shah Sunita Bhalla Ashish Kumar | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，7： | 5 |
| 2 | Phenotypic instability and rapid gene silencing in newly formed Arabidopsis alloteraploids显示文摘 | Comai L Tyagi A P Winter K Holmes-Davis R Reynolds S H Stevens Y Byers B | 2000 | Plant Cell2000，12，9： | 2 |
| 3 | Susceptibility to tuberculo- sis: clues from studies with inbred and outbred New Zealand White rabbits显示文摘 | Dorman S E Hatem C L Tyagi S | 2004 | Infect Immun2004，72，3： | 1 |
| 4 | Assessment ofgroundwater contamination from fertilizers in the Delhi area based on ^18 O, NO3 and K^+ composition 显示文摘 | Datta P S Deb D L Tyagi S K | 1997 | Journal of Contaminant Hydrology1997，，27： | 1 |
| 5 | Sludge: A waste or renewable sourcefor energy and resources recovery-显示文摘 | Tyagi V K Lo S L | 2013 | Renewable andSustainable Energy Reviews2013，25，： | 1 |
| 6 | Proteinases and restenosis in the human coronary artery:extracellular matrix production exceeds the expression of proteolytic activity显示文摘 | Tyagi SC Meyer L Schahz R A | 1995 | Atherosc- lerosis1995，1，16： | 1 |
| 7 | Silibinin efficacy against human hepatocellnlar carcinoma显示文摘 | Varghese L Agarwal C Tyagi A | 2005 | Clin Cancer Res2005，11，23： | 1 |
| 8 | Water management--A tool for methane mitagation from irrigated paddy fields显示文摘 | Tyagi L Kumari B Singh S N | 2010 | Science of the Total Environment2010，408，： | 1 |
| 9 | Proteinases and restenosis in the human coronary artery:extracellular matrix production exceeds the expression of proteolytic activity显示文摘 | Tyagi SC Meyer L Schmaltz RA Reddy HK | 1995 | Atherosclerosis1995，116，1： | 1 |
| 10 | Wastewater treatment sludge as raw material for Bacillus thuringiensis production显示文摘 | TIRADO-MONTIEL M L TYAGI R D VALERO J R | 2001 | Water Res2001，35，16： | 1 |
| 11 | Act vation of extracellular matrix metalloproteinases in equine laminitis 显示文摘 | JOHNSON P J TYAGI S C KATWA L C | 1998 | Veterinary Record1998，142，15： | 1 |
| 12 | Direct extraction and estimation of collagenase activity by zymography in microquantities of rat myocardium and uterus显示文摘 | Tyagi SC Matsubara L Weber KT | 1993 | Clin Biochem1993，26，： | 1 |
| 13 | Molecular beacons-spectral genotyping of human allele显示文摘 | Kostrikis L G Tyagi S Mhlanga M M Ho D D Kramer F R | 1998 | Science1998，279，： | 1 |
| 14 | Microwave irradiation: a sustainable way for sludge treatment and resource recovery显示文摘 | TYAGI V K LO S L | 2013 | Renew Sustain Energy Rev2013，18，10： | 1 |
| 15 | Referral delay and ocular surgical outcome in Terson syndrom显示文摘 | Gnanaraj L Tyagi AK Cottrell DG Fetherston TJ Richardson J Stannard KP | 2000 | Retina2000，20，： | 1 |
| 16 | Production of biopesticides using wastewater sludge as a raw material-effect of process parameters显示文摘 | TIRADO M M L TYAGI R D VALERO J R | 2003 | Water Science and Technology2003，48，8： | 1 |
| 17 | Proteinases and restenosis in the human coronary artery:extracellular matrix production exceeds the expression of proteolytic activiry显示文摘 | Tyagi SC Meyer L Schmaltz RA | 1995 | Atherosclerosis1995，116，： | 1 |
| 18 | Direct extraction and estimation of collagenase(s) activity by zymography in microquantities of rat myocardium and uterus显示文摘 | Tyagi SC Matsubara L Weber KT | 1993 | Clin Biochem1993，26，3： | 1 |
| 19 | Effects of microwave and alkali induced pretreatment on sludge solubilization and subsequent aerobic digestion activated sludge by pretreatment显示文摘 | Chang C J Tyagi V K Lo S L | | 0，，： | 1 |
| 20 | Elevated temperature ffibological behavior of Ni based composites containing nano-silver andhBN显示文摘 | TYAGI R XIONG D S LI J L | 2010 | Wear2010，269，： | 1 |
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