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| 1 | History and possible mechanisms of prehistoric human migration to the Tibetan Plateau显示文摘Prehistoric human history on the Tibetan Plateau is a hotly debated topic. Archaeological research on the plateau during the past few decades has enormously improved our understanding of the topic and makes it possible for us to consider the processes and mechanisms of prehistoric human migration to the region. By reviewing the published archaeological research on the Tibetan Plateau, we propose that the first people on the plateau initially spread into the He-Huang region from the Chinese Loess Plateau, and then moved to the low elevation Northeastern Tibetan Plateau and perhaps subsequently to the entire plateau. This process consisted of four stages.(1) During the climatic amelioration of the Last Deglacial period(15–11.6 ka BP), Upper Paleolithic hunter-gatherers with a developed microlithic technology first spread into the Northeastern Tibetan Plateau.(2) In the early-mid Holocene(11.6–6 ka BP), Epipaleolithic microlithic hunter-gatherers were widely distributed on the northeastern plateau and spread southwards to the interior plateau, possibly with millet agriculture developed in the neighboring low elevation regions.(3) In the mid-late Holocene(6–4 ka BP), Neolithic millet farmers spread into low elevation river valleys in the northeastern and southeastern plateau areas.(4) In the late Holocene(4–2.3 ka BP), Bronze Age barley and wheat farmers further settled on the high elevation regions of the Tibetan Plateau, especially after 3.6 ka BP. Finally, we suggest that all of the reported Paleolithic sites earlier than the LGM on the Tibetan Plateau need further examination. | ZHANG DongJu DONG GuangHui WANG Hui REN XiaoYan HA PiPu'u QIANG MingRui CHEN FaHui | 2016 | Science China Earth Sciences2016，59，9： | 20 |
| 2 | Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model显示文摘Objective: To investigated the anti-inflammatory and antimicrobial effects of anthocyanins extracted from black soybean on the chronic bacterial prostatitis(CBP) rat model.Methods: The SpragueDawley rats were divided into 4 groups,including control,ciprofloxacin,anthocyanins and anthocyanins with ciprofloxacin groups(n=8 in each group).Then,drip infusion of bacterial suspension(Escherichia coli Z17O_2:K_1:H^-) into Sprague-Dawley rats was conducted to induce CBP.In 4 weeks,results of prostate tissue,urine culture,and histological analysis on the prostate were analyzed for each group.Results: The use of ciprofloxacin,anthocyanins,and anthocyanins with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in the reduction of prostatic inflammation compared with the control group(P<0.05).The anthocyanins with ciprofloxacin group showed a statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the ciprofloxacin group(P<0.05).Conclusions: These results suggest that anthocyanins may have anti-inflammatory and antimicrobial effects,as well as a synergistic effect with ciprofloxacin.Therefore,we suggest that the combination of anthocyanins and ciprofloxacin may be effective in treating CBP to obtain a higher rate of treatment success. | Byung Il Yoon Woong Jin Bae Yong Sun Choi Su Jin Kim U Syn Ha Sung-Hoo Hong Dong Wan Sohn Sae Woong Kim | 2018 | Chinese Journal of Integrative Medicine2018，24，8： | 11 |
| 3 | ZnO nanotube by template wetting process显示文摘 | SEO B I SHAISLAMOV AMOV U A HA M H | 2007 | Physica E2007，，37： | 1 |
| 4 | Mullerian inhibiting substance inhibits breast cancer cell growth through an NFkB imediated pathway显示文摘 | Segev D L Ha T U Tran T T | 2000 | J Biol Chem2000，15，28： | 1 |
| 5 | Intraindividual comparative animal study of alpha-and beta-tricalcium phosphate degradation in conjunction with simultaneous insertion of dental implants显示文摘 | Merten HA Wiltfang J Grohmann U | 2001 | J Craniofac Surg2001，12，1： | 1 |
| 6 | 显示文摘 | Seo B I Shaislamov U A Ha M H | 2007 | Physica E2007，，37： | 1 |
| 7 | Biomechanical evaluation of vertebmplasty And kypho- plasty with polymethylmethacrylate or calcium phosp- hate cement under Cyclic loading 显示文摘 | Wilke HA Mehnert U Claes LE | 2006 | Spine ( Phila Pa 1976 )2006，31，25： | 1 |
| 8 | ZnO nanotubes by template wetting process 显示文摘 | SEO B I SHAISLAMOV U A HA M H | 2007 | Physica: E2007，37，12： | 1 |
| 9 | Inhibition of Proliferation of Prostate Cancer Cell Line DU-145 in vitro and in vivo Using Salvia miltiorrhiza Bunge显示文摘Objective:To investigate the antiproliferative activity of Salvia miltiorrhiza Bunge.(SM)on the castration-resistant prostate cancer(CRPC)cell line DU-145 in vitro and in vivo.Methods:Prostate cancer cell line(DU-145)and normal prostate cell line(RWPE-1)were treated with SM at different concentrations(3.125,12.5,25 and 50μg/mL)to investigate the antiproliferative effects.DNA laddering analysis was performed to investigate the apoptosis of DU-145 cells.Molecular mechanism was investigated by Western blot analysis of p53,Bcl-2,prostate specific antigen(PSA),and androgen receptor(AR).Six-week-old male BALB/c nude mice were randomly divided into normal control group(n=101)and treated group(n=101)which administered 500 mg/kg SM for 2 weeks.Tumor volumes were measured.Results:Treatment with SM resulted in a dose-dependent decrease in cell number of DU-145 cells in comparison with RWPE-1.DNA laddering analysis indicated the apoptosis of DU-145 cells.Treatment with SM increased the expression of p53 and reduced the expression of Bcl-2 proteins.The levels of PSA were considerably reduced in SM-treated group compared to the controls,and a decrease in AR expression was observed when cells were treated with SM in the same pattern as a reduction in PSA.In the tumour xenograft study,SM given once a day for 2 weeks significantly inhibited tumour growth.Conclusion:SM might contribute to the anticancer actions such as induction of apoptosis and inhibition of proliferation of prostate cancer cells. | Woong Jin Bae Jin Bong Choi Kang Sup Kim U Syn Ha Sung Hoo Hong Ji Youl Lee Tae-Kon Hwang Sung Yeoun Hwang WANG Zhi-ping Sae Woong Kim | 2020 | Chinese Journal of Integrative Medicine2020，26，7： | 1 |
| 10 | Treatment compliance and safety of aceclofenac versus standard NSADs in patients with common arthritic disorders:a meta-analysis显示文摘 | Bird HA Semi U | 1996 | Eur J Rheumatol Inflamm1996，6，1： | 1 |
| 11 | Grain Size effects on the mechanical properties of some squeeze cast light alloys显示文摘 | Ha H U Musson N J | 1995 | Journal of Materials Science1995，30，： | 1 |
| 12 | HVTEM insitu observations vations of dislocation motion in the oxide dispersion strengthened superalloy MA754显示文摘 | Bartsch M Messerschmidt U | 2001 | Acta Mater2001，49，： | 1 |
| 13 | Surgical excision vs Mohs’ micrographic surgery for basal-cell carcinoma of the face: randomised controlled trial显示文摘 | Nicole WJ Smeets Gertruud AM Krekels Judith U Ostertag Brigitte AB Essers Carmen D Dirksen Fred HM Nieman HA Martino Neumann | 2004 | The Lancet2004，，9447： | 1 |
| 14 | Suppression of Oxidative Stress of Modified Gongjin-Dan (WSY^1075) in Detrusor Underactivity Rat Model Bladder Outlet Induced by Obstruction显示文摘Objective: To investigate the anti-oxidative stress and preventive effect of modified Gongjin-dan(WSY-1075) in a detrusor underactivity rat model. Methods: Rats were randomly allocated to three groups: shamoperated(control), bladder outlet obstruction-induced detrusor underactivity(BOO-DU), and BOO-DU with WSY-1075(WSY) groups. WSY-1075 was oral y administrated to rats 200 mg daily for 2 weeks prior to the operation and 4 weeks after the operation. Bladder outlet obstruction was surgical y induced in rats by ligation around the urethra avoiding total obstruction. Cystometrography was conducted on rats in each group for examination of bladders. Results: Compared with the control group, bladder outlet obstruction led to a significant increase in oxidative stress with consequent changes to molecular composition, and decrease in maximal detrusor pressure(P<0.05). WSY-1075 treatment significantly suppressed oxidative stress and prevented degenerative and dysfunctional changes in bladder, as compared with BOO-DU group(P<0.05). Conclusion: WSY-1075 had beneficial effect on prevention of BOO-DU. | Jin-Woo Jung Seung Hwan Jeon Woong Jin Bae Su Jin Kim Mun Su Chung Byung II Yoon Sae Woong Choi U Syn Ha Sung Yeoun Hwang Sae Woong Kim | 2018 | Chinese Journal of Integrative Medicine2018，24，9： | 1 |
| 15 | Characteristics of composite bipolar plates for polymer electrolyte membrane fuel cells 显示文摘 | CHO E A JEON U S HA H Y | 2004 | J Power Sources2004，125，： | 1 |
| 16 | Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life 显示文摘 | Gehring U Wijga AH Brauer M Fischer P de Jongste JC Kerkhof M Oldenwening M Smit HA Brunekreef B | 2010 | Am J Respir Crit Care Med2010，181，6： | 1 |
| 17 | ACD44 variant exon 6 epitope as a prognostic indicator in breast cancer 显示文摘 | Schumacher U Homy HP Horsst HA | 1996 | Eur J Surg Oncol1996，22，3： | 1 |
| 18 | The effects of perindopril on QT duration and dispertion in patients with coronary slow flow 显示文摘 | GUNTEKIN U GUMRUKCUOGLU HA GUNES Y | 2011 | Heart Vessels2011，26，4： | 1 |
| 19 | Viability of microencapsulated Bifidobacteria in set yogurt during refrigerated storage显示文摘 | Adhikari K Mustap Ha A Grun I U | 2000 | Journal of Dairy Science2000，83，： | 1 |
| 20 | Ischemia - reper- fusion damage of the liver caused by free radicals-direct detec- tion using electron spin resonance(ESR)显示文摘 | KUNZ R BRUNE HA ZIEGLER U | 1991 | Langenbecks ArchChir1991，376，： | 1 |
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