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1Relationship between adipose tissue dysfunction, vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is the most common chronic liver disease worldwide.Its pathogenesis is complex and not yet fully understood.Over the years many studies have proposed various pathophysiological hypotheses,among which the currently most widely accepted is the'multiple parallel hits'theory.According to this model,lipid accumulation in the hepatocytes and insulin resistance increase the vulnerability of the liver to many factors that act in a coordinated and cooperative manner to promote hepatic injury,inflammation and fibrosis.Among these factors,adipose tissue dysfunction and subsequent chronic low grade inflammation play a crucial role.Recent studies have shown that vitamin D exerts an immune-regulating action on adipose tissue,and the growing wealth of epidemiological data is demonstrating that hypovitaminosis D is associated with both obesity and NAFLD.Furthermore,given the strong association between these conditions,current findings suggest that vitamin D may be involved in the relationship between adipose tissue dysfunction and NAFLD.The purpose of this review is to provide an overview of recent advances in the pathogenesis of NAFLD in relation to adipose tissue dysfunction,and in the pathophysiology linking vitamin D deficiency with NAFLD and adiposity,together with an overview of the evidence available on the clinical utility of vitamin D supplementation in cases of NAFLD.Flavia A Cimini Ilaria Barchetta Simone Carotti Laura Bertoccini Marco G Baroni Umberto Vespasiani-Gentilucci Maria-Gisella Cavallo Sergio Morini 2017World Journal of Gastroenterology2017,23,19:9
2A digital approach to clock recovery in generalized minimum shift keying显示文摘D'ANDREA A N UMBERTO M RUGGERO R 1990IEEE Transactions on Vehicle Technology1990,39,:1
3Microprocessor- Controlled Nanovolt Measurements 显示文摘ERNESTO A UMBERTO Potentiometric System for P 1978IEEE Transactions On Instrumentation And Measurement1978,,:1
4Spark plasma sintering: A high strain rate low temperature forming tool for ceramics显示文摘JIANG Dong-tao Hulbert D M Kuntz J D Umberto Anselmi-Tamburini Mukherjee A K 2007Mater Sci Eng A2007,463,12:1
5Principal components analysis applied to performance and carcass traits in the chicken显示文摘Luís Fernando Batista P Irineu Umberto P Cláudio Manoel Rodrigues D M M^onica Corrêa L Luiz Lehmann C 2006Anim Res2006,55,:1
6L-valve behavior with solids of different size and density显示文摘Umberto A Cesare B L Antonio C 1998Powder Technology1998,98,3:1
7Dose-denseand high-dose chemotherapy plus rituximab withautologous stem cell transplantation for primary treatmentof diffuse large B-cell lymphoma with a poor prognosis : aphase II multicenter study 显示文摘Umberto V Annalisa C Emanuele A 2009Haematologica2009,94,9:1
8Worldwide phylogeography of wild boar reveals multiple centers of pig domestication显示文摘Greger L Keith D Umberto A 2005Science2005,307,5715:1
9Acute combination fracture of arias and axis: 'triple' anterior screw fixation in a 92-year-old man Technical note 显示文摘Umberto A Luciano M 2006Surgical Neurology2006,65,:1
10Reactive growth of niobium silicides in bulk diffusion couples显示文摘CHIARA M VINCENZO B FILIPPO M UMBERTO A T 2003Acta Matedalia2003,51,:1
11Factors related to orthostatic hypotension in Parkinson’s disease显示文摘Santiago Perez-Lloret María Verónica Rey Nelly Fabre Fabienne Ory Umberto Spampinato Jean-Michel Senard Anne Pavy-Le Traon Jean-Louis Montastruc Olivier Rascol 2012Parkinsonism and Related Disorders2012,,5:1
12Regulatory Roles of IL-2 and IL-4 in H4/Inducible Costimulator Expression on Activated CIM + T Cells During Tb Cell Development 显示文摘Junji Y Yutaka A Umberto D 2003Immunol2003,18,6:1
13Factors related to orthostatic hypotension in Parkinson’s disease显示文摘Santiago Perez-Lloret María Verónica Rey Nelly Fabre Fabienne Ory Umberto Spampinato Jean-Michel Senard Anne Pavy-Le Traon Jean-Louis Montastruc Olivier Rascol 2012Parkinsonism and Related Disorders2012,,5:1
14Added Value of ^sup 99m^Tc-HMPAO-Labeled Leukocyte SPECT/ CT in the Characterization and Management of Patients with Infectious Endocarditis显示文摘Erba Paola A Conti Umberto Lazzeri Elena Sollini Martina Doria Roberta De Tommasi Salvatore M Bandera Francesco Tascini Carlo Menichetti Francesco Dierckx Rudi A J O Signore Alberto Mariani Giuliano 2012EN2012,,8:1
15Self-propagating exothermic reactions:The synthesis of high-temperature materials by combustion显示文摘Munir Z A Umberto R 1989Materials Science Reports1989,,3:1
16Microscopic enteritis:Bucharest consensus显示文摘Microscopic enteritis(ME) is an inflammatory condition of the small bowel that leads to gastrointestinal symptoms,nutrient and micronutrient deficiency.It is characterised by microscopic or sub-microscopic abnormalities such as microvillus changes and enterocytic alterations in the absence of definite macroscopic changes using standard modern endoscopy.This work recognises a need to characterize disorders with microscopic and submicroscopic features,currently regarded as functional or non-specific entities,to obtain further understanding of their clinical relevance.The consensus working party reviewed statements about the aetiology,diagnosis and symptoms associated with ME and proposes an algorithm for its investigation and treatment.Following the 5th International Course in Digestive Pathology in Bucharest in November 2012,an international group of 21 interested pathologists and gastroenterologists formed a working party with a view to formulating a consensus statement on ME.A five-step agreement scale(from strong agreement to strong disagreement) was used to score 21 statements,independently.There was strong agreement on all statements about ME histology(95%-100%).Statements concerning diagnosis achieved 85% to 100% agreement.A statement on the management of ME elicited agreement from the lowest rate(60%) up to 100%.The remaining two categories showed general agreement between experts on clinical presentation(75%-95%) and pathogenesis(80%-90%) of ME.There was strong agreement on the histological definition of ME.Weaker agreement on management indicates a need for further investigations,better definitions and clinical trials to produce quality guidelines for management.This ME consensus is a step toward greater recognition of a significant entity affecting symptomatic patients previously labelled as non-specific or functional enteropathy.Kamran Rostami David Aldulaimi Geoffrey Holmes Matt W Johnson Marie Robert Amitabh Srivastava Jean-Francois Fléjou David S Sanders Umberto Volta Mohammad H Derakhshan James J Going Gabriel Becheanu Carlo Catassi Mihai Danciu Luke Materacki Kamran Ghafarzadegan Sauid Ishaq Mohammad Rostami-Nejad A Salvador Pe?a Gabrio Bassotti Michael N Marsh Vincenzo Villanacci 2015World Journal of Gastroenterology2015,21,9:1
17Synchronization for differential transmitted reference receivers显示文摘ANTONIO A D UMBERTO M LORENZO T 2007IEEE Transactions on Wireless Communications2007,6,:1
18Real-time polymerase chain reaction approach for quantitation of ruminantspecific DNA to indicate a correlation between DNA amount and meat and bone meal heat treatments显示文摘Barbara C Gianfranco B Umberto A 2005Journal of AOAC International2005,88,5:1
19Functionalizated polymers from Ziegler-Natta catalysts显示文摘MAURIZIO G UMBERTO G ENRICO A 1995Journal of Molecular Catalysis A: Chemical1995,101,:1
20Effects of Cytokines and Endotoxin on the Endotoxin on the Intraeellular Growth of Baeteria显示文摘Siva Kanangat Umberto Meduri G Elizabeth A Tolley 1999Infection and Immunity1999,6,:1
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