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| 1 | Methods for the development and assessment of atrial fibrillation and heart failure dog models显示文摘与动物的发展报导 Medtronic 经验的目的用为 AF 模型,的为 CHF.Methods 的为 AF 和 microemboli 的高率的踱步为 atrial 纤维性颤动( AF )和长期的心失败( CHF )当模特儿一根 atrial 皮带被纳入 Medtronic 协同作用 neurostimulator ,它被规划在开关责任 cycle.Atrial natnuretic 肽( ANP )在 50 Hz 刺激,大脑 natriuretic 肽( BNP )和N终端职业人员大脑 natriuretic 肽( NT-proBNP )皮脂腺囊瘤;在精选时间 points.For CHF 模型,的 assayed 在 62,400 beads/mL 的 90 m 聚苯乙烯 microspheres 的连续注射( Polybead , Polysciences 公司)被执行导致全球局部缺血,有每周监视的任何一个和 embolization 时间表(集团 1 , n = 25 )或与监视的双周刊和 emboliation 时间表(集团 2 , n36 ) .Echocardiograms 每周与 ventriculograms 和磁性的回声成像扫描一起被使用估计心脏的功能和 ANP , BNP 和 NT-proBNP 是为 AF 模型的 monitored.Results ,为 CHF 模型,遇见 CHF 端点的日子在集团 2 .For 在集团 1 和 89 是 116 AF 和 CHF 模型, NT-proBNP 与在为动物的搜索的研究人员为估计基于设备的治疗的安全和功效建模的我们为 AF 和 CHF 狗模型的发展和评价的经验可以帮助的疾病 states.Conclusion 的发展相关很好。 | Jon F Urban Renee L Gerhart Jason R Krzeszak Corey R Leet Linnea R Lentz Carolyn B McClay | 2011 | Journal of Geriatric Cardiology2011，8，3： | 3 |
| 2 | Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair显示文摘AIM To determine endothelin-1(ET-1)concentration before and after surgical coarctectomy and evaluate its association with left ventricular geometric change.METHODSA prospective,cohort study of 24 patients aged 2 d to 10years with coarctation of the aorta undergoing surgical repair.A sub-cohort of patients with age<1 mo was classified as'neonates'.Echocardiograms were performed just prior to surgery and in the immediate post-op period to assess left ventricle mass index and relative wall thickness(RWT).Plasma ET-1 levels were assessed at both time points.Association between ET-1 levels and ventricular remodeling was assessed.RESULTSPatients<1 year demonstrated higher pre-op ET-1 than post-op(2.8 pg/m L vs 1.9 pg/m L,P=0.02).Conversely,patients>1 year had no change in ET-1 concentration before and after surgery(1.1 vs 1.4,NS).Pre-op,patients<1 year demonstrated significantly higher ET-1 than older children(2.8 vs 1.1,P=0.001).Post-op there was no difference between the age groups(1.9 vs 1.4,NS).Neither RWT nor left ventricle mass index(LVMI)varied from pre-op to post-op.The subset of neonates showed a strong positive correlation between pre-op ET-1 and RWT(r=0.92,P=0.001).Patients with ET-1>2 pg/m L preop demonstrated higher LVMI(65.7 g/m^(2.7) vs 38.5 g/m^(2.7),P=0.004)and a trend towards higher RWT(45%vs39%,P=0.07)prior to repair than those with lower ET-1concentration.CONCLUSIONET-1 concentration is significantly variable in the perioperative period surrounding coarctectomy.Older children and infants have different responses to surgical repair suggesting different mechanisms of activation. | Benjamin Steven Frank Tracy T Urban Suhong Tong Courtney Cassidy Max B Mitchell Christopher S Nichols Jesse A Davidson | 2017 | World Journal of Cardiology2017，9，12： | 2 |
| 3 | Prospectively gated transverse coronary CT angiography versus retrospectively gated helical technique: improved image quality and reduced radiation dose显示文摘 | Earls J P Berman E L Urban B A | 2008 | Radiology2008，246，3： | 1 |
| 4 | Soluble adhesion molecules ( sICAM-1, sVCAM-1 ) and selectins ( sE selectin sP selectin, sL seleetin) levels in children and adolescents with obesity, hypertension, and diabetes 显示文摘 | Glowinska B Urban M Peczynska J | 2005 | Metabolism2005，54，8： | 1 |
| 5 | Portalphase contrast-enhanced helical CT for the detection of malignant hepatic tumors:Sensitivity based on comparison with intraoperative and pathologic findings显示文摘 | KUSZYK B S BLUEMKE D A URBAN B A | 1996 | Am J Rcentgenol1996，166，1： | 1 |
| 6 | A simple meth- od for estimating potential relative radiation (PRR)for land- scape-scale vegetation analysis显示文摘 | PIERCE K B LOOKINGBILL T URBAN D | 2005 | Landscape Ecology2005，20，2： | 1 |
| 7 | M48 Severn Bridge-Main Cable Inspection and Rehabilitation显示文摘 | Cocksedge C Hudson T Urbans B a al | 2010 | Bridge Engineering2010，163，4： | 1 |
| 8 | Structure and Soot Properties of Nonbuoyant Ethylene/Air Laminar Jet Diffusion Flames 显示文摘 | Urban D L Yuan Z G Sunderland P B | 1998 | AIAA Journal1998，36，8： | 1 |
| 9 | Anterior hypopituitarism foil owing traumatic brain injury显示文摘 | Urban RJ Harris P Masel B | 2005 | Brain Injury2005，19，5： | 1 |
| 10 | Current assessment of targets and theories of anaesthesia显示文摘 | Urban B W | 2002 | Br J Anaesthesia2002，89，1： | 1 |
| 11 | Dexmedetomidine versus propofol for sedation of ventilated spinal patients显示文摘 | Urban MK Wukovits B Flynn E | 2004 | Anesthe- siology2004，101，3： | 1 |
| 12 | Magnetic resonance imaging of perianal fistulas : predictive value for Parks clas- sification and identification of the internal opening 显示文摘 | Holzer B Rosen HR Urban M | 2000 | Color CT Dis2000，2，： | 1 |
| 13 | Soo- ting limits of microgravity spherical diffusion flames in oxygen -enriched air and diluted fuel显示文摘 | Sunderland P B Urban D L Stocker D P | 2004 | Combustion science and technology2004，176，12： | 1 |
| 14 | Utilization of Die Components Fed Blended or Separately to Lactating Cows显示文摘 | Holter J B Urban W E Hayes H H | 1977 | Journal of dairy science1977，60，8： | 1 |
| 15 | Fast ground State Manipulation of Neutral Atoms in Microscopic Optical Traps 显示文摘 | YAVUZ D D KULATUNGA P B URBAN E | 2006 | Phys Rev Lett2006，96，06： | 1 |
| 16 | Sympathoinhibition by rilmenidine in conscious rabbits: involvement of a2-adren-oceptors显示文摘 | Szabo B Urban R Starke K | 1993 | Arch Pharmacol1993，348，： | 1 |
| 17 | Potential response of pacific northwestern forests to climate change :effects of stand age and initial composition 显示文摘 | Urban D L Harmon M E Halpern C B | 1993 | Climatic Change1993，23，： | 1 |
| 18 | Anterior hy- popituitafism following traumatic brain injury显示文摘 | Urban R J Harris P Masel B | 2005 | Brain Inj2005，19，： | 1 |
| 19 | Synthesis of optically-active 2-benzyldihydrobenzopyrans for the hypoglycemic agent englitazone显示文摘 | URBAN F J MOORE B S | 1992 | Journal of Heterocyclic Chemistry1992，29，2： | 1 |
| 20 | Premarket forecasting of really-new products显示文摘 | URBAN G L WEINBERG B D HAUSER J R | 1996 | Journal of Marketing1996，60，1： | 1 |
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