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| 1 | Multiligament knee injuries with associated tibial plateau fractures: A report of two cases显示文摘The management of a combination of fracture and multiligament knee injury(MKI) in traumatic knee injury remains controversial, and there are evolving treatment recommendations. Currently, there are no studies focusing on older adult patients with MKI's in combination with tibia fractures. As a result, there is no well-established treatment algorithm for older adult patients with these complex injuries. We report two cases of MKI's with concomitant fractures in patients fifty years of age or older. Both patients were treated surgically for their associated tibial plateau fractures, but were managed with conservative treatment of the multiligamentous knee injuries. We also provide a review of the literature and guidelines for older adult patients with these types of complex traumatic injuries. Early to mid term acceptable outcomes were achieved for both patients through surgical fixation of the tibial plateau fracture and conservative treatment of the ligament injuries. We propose a comprehensive treatment algorithm for management of these complex injuries. | Vani J Sabesan Paul J Danielsky Abby Childs Tom Valikodath | 2015 | World Journal of Orthopedics2015，6，3： | 14 |
| 2 | Colon cancer and the epidermal growth factor receptor:Current treatment paradigms,the importance of diet,and the role of chemoprevention显示文摘Colorectal cancer represents the third most common and the second deadliest type of cancer for both men and women in the United States claiming over 50000 lives in 2014. The 5-year survival rate for patients diagnosed with metastatic colon and rectal cancer is < 15%. Early detection and more effective treatments are urgently needed to reduce morbidity and mortality of patients afflicted with this disease. Here we will review the risk factors and current treatment paradigms for colorectal cancer, with an emphasis on the role of chemoprevention as they relate to epidermal growth factor receptor(EGFR) blockade. We will discuss how various EGFR ligands are upregulated in the presence of Western diets high in saturated and N-6 polyunsaturated fats. We will also outline the various mechanisms of EGFR inhibition that are induced by naturally occurring chemopreventative agents such as ginseng, green tea, and curcumin. Finally, we will discuss the current role of targeted chemotherapy in colon cancer and outline the limitations of our current treatment options, describing mechanisms of resistance and escape. | Baldeep Pabla Marc Bissonnette Vani J Konda | 2015 | World Journal of Clinical Oncology2015，6，5： | 7 |
| 3 | Foaming properties of selected plant and animal显示文摘 | Vani B Zayas J F | 1995 | Journal of Food Science1995，60，5： | 1 |
| 4 | Foaming properties of selected plant and animal protein 显示文摘 | Bolnedi Vani Zayas J F | 1995 | Food Science1995，，60： | 1 |
| 5 | Trends in surgicall site infections in general surgery at a tertiary hospital显示文摘 | Reddy BR Vani J Gade PS | 2012 | J Med Allid Sci2012，2，1： | 1 |
| 6 | Role of natural antibodies in immune homeostasis:IVIg perspective显示文摘 | Vani J Elluru S Negi VS | 2008 | Autoimmun Rev2008，7，6： | 1 |
| 7 | Inhibition of dif- ferentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin显示文摘 | MADDUR M S VANI J HEGDE P | 2011 | J Allergy Clin Immunol2011，127，3： | 1 |
| 8 | Synovial lipomatosis: A rare cause of knee pain in an adolescent female显示文摘Synovial lipomatosis is a benign proliferative disease of the subsynovial adipose which can lead to a variety of presentations. Cases of synovial lipomatosis in children or adolescents are rare. This case report describes an adolescent patient with a rare bilateral presentation of synovial lipomatosis. She had been treated for years prior to her presentation for juvenile idiopathic arthritis. She presented with chronic bilateral knee pain, swelling, and mechanical symptoms. Bilateral MR imaging demonstrated effusions, hypertrophy of the synovium, and polyp-like projections of tissue with the same signal intensity as fat which is pathognomonic for synovial lipomatosis. Arthroscopic synovectomy and extensive debridement of polyp like fat projections of the right knee was performed. Histopathology was consistent with the synovial lipomatosis diagnosis. Postoperatively, the patient was satisfied with her outcome with improved pain relief and function in her right knee. | Nicholas Miladore Mary A Childs Vani J Sabesan | 2015 | World Journal of Orthopedics2015，6，3： | 1 |
| 9 | Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin 显示文摘 | Maddur MS Vani J Hcgde P | 2011 | J Allergy Clin Immunol2011，127，3： | 1 |
| 10 | Trends in surgicall site infections in general surgery at a tertiary hospital显示文摘 | Reddy BR Vani J Gade PS | 2012 | J Med Allied Sci2012，2，1： | 1 |
| 11 | Inhibition of differentiation,amplification,and function of human TH17 cells by intravenous immunoglobulin显示文摘 | Maddur MS Vani J Hegde P | 2011 | J Allergy Clin Immunol2011，127，3： | 1 |
| 12 | TLR 9 activation in dendritic cells enhances salmonella killing and antigen presentation via involvement of the reactive oxygen species 显示文摘 | Lahiri A Das P Vani J | 2010 | PloS One2010，5，10： | 1 |
| 13 | Thediagnostic dilemma of ventilator - associated pneumonia in criticallyill children显示文摘 | Vani Venkatachalam- J O wenllendley- Douglas F Willson | 2011 | Pediatr Crit Care Med2011，12，3： | 1 |
| 14 | Role of natural antibodies in immune homeostasis: IVIg perspeetive显示文摘 | Vani J Elluru S Negi V-S | 2008 | Autoimmun Rev2008，7，6： | 1 |
| 15 | Wheat germ protein solubility and water retention显示文摘 | Vani B Zayas J F | 1995 | J Food Sci1995，60，4： | 1 |
| 16 | Foaming properties of selected plant and animal proteins 显示文摘 | Vani B Zayas J F | 1995 | Journal of Food Science1995，60，5： | 1 |
| 17 | Foaming properties of selected plant and animal protein显示文摘 | Bolnedi Vani Zayas J F | 1995 | J Food Sci1995，60，： | 1 |
| 18 | Inhibition of dif ferentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin显示文摘 | Maddur MS Vani J Hegde P | 2011 | J Al- lergy Clin Immunol2011，27，： | 1 |
| 19 | Foaming properties of selected plant and animal protein显示文摘 | Vani B Zayas J F | 1995 | Journal of food science1995，60，5： | 1 |
| 20 | Impact of gpl20 on dendritic celt-derived chemokines : relevance for the efficacy of gpl20 - based vaccines for HIV-I显示文摘 | Vani J Sharma M Shaila MS | 2012 | Clini Vacc Imm2012，19，8： | 1 |
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