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28篇 您的检索式：作者名="VENU M"

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	题名	作者	年代	出处	被引量
1	Maternal and perinatal magnesium restriction predisposes rat pups to insulin resistance and glucose intolerance 显示文摘	VENU L KISHORE Y D RAGHUNATH M	2005	The Journal of Nutrition2005，135，6：	1
2	The next-generation sphingosine-1 receptor modulator BAF312(siponimod) improves cortical network functionality in focal autoimmune encephalomyelitis显示文摘Autoimmune diseases of the central nervous system(CNS) like multiple sclerosis(MS) are characterized by inflammation and demyelinated lesions in white and grey matter regions. While inflammation is present at all stages of MS, it is more pronounced in the relapsing forms of the disease, whereas progressive MS(PMS) shows significant neuroaxonal damage and grey and white matter atrophy. Hence, disease-modifying treatments beneficial in patients with relapsing MS have limited success in PMS. BAF312(siponimod) is a novel sphingosine-1-phosphate receptor modulator shown to delay progression in PMS. Besides reducing inflammation by sequestering lymphocytes in lymphoid tissues, BAF312 crosses the blood-brain barrier and binds its receptors on neurons, astrocytes and oligodendrocytes. To evaluate potential direct neuroprotective effects, BAF312 was systemically or locally administered in the CNS of experimental autoimmune encephalomyelitis mice with distinct grey-and white-matter lesions(focal experimental autoimmune encephalomyelitis using an osmotic mini-pump). Ex-vivo flow cytometry revealed that systemic but not local BAF312 administration lowered immune cell infiltration in animals with both grey and white matter lesions. Ex-vivo voltage-sensitive dye imaging of acute brain slices revealed an altered spatio-temporal pattern of activation in the lesioned cortex compared to controls in response to electrical stimulation of incoming white-matter fiber tracts. Here, BAF312 administration showed partial restore of cortical neuronal circuit function. The data suggest that BAF312 exerts a neuroprotective effect after crossing the blood-brain barrier independently of peripheral effects on immune cells. Experiments were carried out in accordance with German and EU animal protection law and approved by local authorities(Landesamt für Natur, Umwelt und Verbraucherschutz Nordrhein-Westfalen;87-51.04.2010.A331) on December 28, 2010.	Petra Hundehege Manuela Cerina Susann Eichler Christian Thomas Alexander M. Herrmann Kerstin Goel Thomas Müntefering Juncal Fernandez-Orth Stefanie Bock Venu Narayanan Thomas Budde Erwin-Josef Speckmann Heinz Wiendl Anna Schubart Tobias Ruck Sven G. Meuth	2019	Neural Regeneration Research2019，14，11：	1
3	Tau mediated neurodegeneration: an insight into Alzheimer's disease pathology显示文摘	Obulesu M Venu R Somashekhar R	2011	Neurochem Res2011，36，：	1
4	Maternal and perinatal magnesium restriction predisposes rat pups to insulin resistance and glucose intolerance显示文摘	Venu L Kishore YD Raghunath M	2005	J Nutr2005，135，6：	1
5	Mechanical activation-assisted solid-state combustion synthesis of insitu aluminum matrix hybrid (AI3Ni/AI203) nanocomposites 显示文摘	REDDY B S B RAJASEKHAR K VENU M	2008	J Alloys Compd2008，465，：	1
6	Red Edge Re- sponse to Forest Leaf Area index显示文摘	Danson F M Plummer Venue S E	1995	International Journal of Remote Sensing1995，36，1：	1
7	Effect of simulated microgravity on Escherichia coli K12 MG1655 growth and gene expression 显示文摘	Arunasri K Adil M Venu Charan K Suvro C Himabindu R S Shivaji S	2013	PLoS One2013，8，57：	1
8	Thrombolysis and adjunctive therapy in acute myocardial infarction:The seventh ACCP conference on antithrombotic and thrombolytic therapy显示文摘	Venu M Robert AH Judith SH	2004	Cardiopulm Crit Care J2004，126，3：	1
9	Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition显示文摘	VENU GP ALAAP BS GEORGE M	2004	J Immunol2004，172，2：	1
10	Strategic resource dynamics of manufacturing firms 显示文摘	Jayanthi S Roth A V Kristal M M Venu L C R	2009	Management Science2009，55，6：	1
11	Me- chanical Activation-Assisted Solid-State Combustion Synthesis of in Situ Aluminum Matrix Hybrid (A13Ni/ A12Oa) Nanocomposites 显示文摘	REDDY B RAJASEKHAR K VENU M	2008	Journal of Alloys and Compounds2008，465，1：	1
12	Laboratory diagnosis and nonoperative management of biliary complications in living donor liver transplant patients显示文摘	VENU M BROWN R D LEPE R	2007	J Clin Gastroenterol2007，41，5：	1
13	Laboratory diagnosis and nonoperative management of biliary complications in living donor liver traosplant patients 显示文摘	Venu M Brown RD Lepe R	2007	J Clin Gastroenterol2007，41，：	1
14	GM-CSF expands dendritic cells and their progenitors in mouse liver显示文摘	Venu GP George M Alaap BS	2003	Hepatolopy2003，37，3：	1
15	Morphological Operators to Extract Channel Network from Digital Elevation Models显示文摘	Dayasagar B S Venu M Srinivas D	2000	International Journal of Remote Sensing2000，21，1：	1
16	Mechanical activation-assisted solid-state combustion synthesis of in situ aluminum matrix hybrid (Al3Ni/A12O3) nanocomposites显示文摘	Reddy B S B Rajasekhar K Venu M		0，，：	1
17	Tau Mediated Neuro- degeneration: An Insight into Alzheimer's Disease Pathology 显示文摘	Obulesu M Venu R Somashekhar R	2011	Neuroche Res2011，36，8：	1
18	Monito- ring damage propagation using PZT impedance trans- ducers显示文摘	Yang Yaowen Liu Hui Venu G M A	2009	Smart Materials and Structures2009，18，04：	1
19	Fisk:Insight into the pathophysiology of twin-twin transfusion syndrome显示文摘	Paula Galea Venu Jain Nicholas M		0，，：	1
20	Application of electromechanical impedance technique for engineering structures: Review and future issues显示文摘	VENU G M CHEEK S	2010	Journal of Intelligent Material Systems and Structures2010，21，1：	1

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