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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Bladder pheochromocytoma:a 3-year follow-up after transurethral resection(TURB)显示文摘 | Baima C Casetta G Vella R | | 0，，： | 1 |
| 3 | Bladder pheochromocytoma: a 3-year follow-up after transurethral resection (TURB)显示文摘 | Baima C Casetta G Vella R | 2000 | Urol Int2000，65，3： | 1 |
| 4 | Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older显示文摘 | Seeman E Vellas B Benhamou C | 2006 | J Bone Miner Res2006，21，7： | 1 |
| 5 | Cutting edge: 4-1BB is a bo- na fide CD8 T cell survival signal显示文摘 | Takahashi C Mittler RS Vella AT | 1999 | J Immunol1999，162，9： | 1 |
| 6 | Implementation of beta-blockade in elderly heart failure patients: role of the nurse specialist 显示文摘 | Mariani M Vella G Bianchi C | 2008 | Eur J Cardiovasc Nur2008，7，3： | 1 |
| 7 | Techniques of Assessing Muscle Mass and Function (Sarcopenia) for Epidemiological Studies of the Elderly显示文摘 | Chumlea W C Guo S S Vellas B | 1995 | J Gerontol A Biol Sci Med Sci1995，50，： | 1 |
| 8 | SPECT during sleepwalking 显示文摘 | Bassettl C Vella S Donati F | 2000 | Lancet2000，356，9228： | 1 |
| 9 | Enhanced replication of M-tropic HIV-1 strains in Herpesvirus saimiri immortalised T-cells which express CCR5显示文摘 | Zheng NN Vella G | 1999 | J Virol Meth1999，79，： | 1 |
| 10 | Alteration in the V1/V2 domain of HIV-2 (CBL24) glycoprotein 105 correlate with an extended cell tropism显示文摘 | King D Zheng NN | 1999 | AIDS Res Hum Ret1999，15，： | 1 |
| 11 | DeltaNp73alpha inhibits PTEN expression in thyroid cancer cells显示文摘 | Vella V Puppin C Damante G | 2009 | Int J Cancer2009，124，11： | 1 |
| 12 | Biadder pheochromocytoma: a 3-year follow-up after transurethral resection ( TURB ) 显示文摘 | Baima C Casetta G Vella R | 2000 | Urol Int2000，65，： | 1 |
| 13 | A Case for Competitive Intelli- gence: 90% of the information a company needs to understand its market and competitors and to make key decisions is already public 显示文摘 | MCGONAGLE J J VELLA C M | 2012 | Revista Intelig~ncia Competitiva2012，2，2： | 1 |
| 14 | Relationships Among Depressive Symptoms, Benefit-Finding, Optimism, and Posi tive Affect in Multiple Sclerosis Patients after Psychothera py for Depression 显示文摘 | Hart S L Vella L Mohr D C | 2008 | Health Psychology2008，27，2： | 1 |
| 15 | A Case for Competitive Intelligence显示文摘 | McGonagle J Vella C | 2002 | Information Management Journal2002，36，4： | 1 |
| 16 | Augmentation of clozapine with an- other pharmacological agent:Treatment for refractory schizophrenia in the 'real world' 显示文摘 | Pai N B Laidlaw M Vella S C | 2012 | Acta Psychiatr Scand2012，126，1： | 1 |
| 17 | Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal显示文摘 | Takahashi C Mittler RS Vella AT | 1999 | J Immunol1999，162，9： | 1 |
| 18 | SPECT during sleep- walking显示文摘 | Bassetti C Vella S Donati F | 2000 | Lancet2000，356，9228： | 1 |
| 19 | The central role of aquaporins in the pathophysiology of ischemic stroke 显示文摘 | Vella J Zammit C Di Giovanni G | 2015 | Front Cell Neurosci2015，9，： | 1 |
| 20 | Multiple myeloma and renal failure:one center's experience显示文摘 | Magec C Vella J P Tormey W P | 1998 | Ren Fail1998，20，： | 1 |
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