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| 1 | Retinopathy of prematurity: Past, present and future显示文摘Retinopathy of prematurity(ROP) is a vasoproliferative disorder of the retina occurring principally in new born preterm infants. It is an avoidable cause of childhood blindness. With the increase in the survival of preterm babies, ROP has become the leading cause of preventable childhood blindness throughout the world. A simple screening test done within a few weeks after birth by an ophthalmologist can avoid this preventable blindness. Although screening guidelines and protocols are strictly followed in the developed nations, it lacks in developing economies like India and China, which have the highest number of preterm deliveries in the world. The burden of this blindness in these countries is set to increase tremendously in the future, if corrective steps are not taken immediately. ROP first emerged in 1940 s and 1950 s, when it was called retrolental fibroplasia. Several epidemics of this disease were and are still occurring in different regions of the world and since then a lot of research has been done on this disease. However, till date very few comprehensive review articles covering all the aspects of ROP are published. This review highlights the past, present and future strategies in managing this disease. It would help the pediatricians to update their current knowledge on ROP. | Parag K Shah Vishma Prabhu Smita S Karandikar Ratnesh Ranjan Venkatapathy Narendran Narendran Kalpana | 2016 | World Journal of Clinical Pediatrics2016，5，1： | 13 |
| 2 | Is myopia a protective factor against central serous chorioretinopathy?显示文摘AIM: To evaluate if any association exists between central serous chorioretinopathy(CSCR) and the refractive status of the eye.· METHODS: This retrospective, institutional, case control study included 499 patients, wherein 262 patients diagnosed as acute CSCR, were compared with an age and gender matched control group of 237 patients. All patients were evaluated with a detailed systemic and ocular history, objective and subjective refractions for both eyes and complete ocular examination by a retina specialist, at all visits. Optical coherence tomography confirmed the diagnosis of CSCR.·RESULTS: The mean age was found to be 40±7y in the study group(Group 1) compared to 38±10y in the control group(Group 2). Most common refractive status in the study group, was emmetropia seen in 191 patients(72.9%), followed by hypermetropia seen in 47 patients(17.9%) and astigmatism seen in 21 patients(8.0%). Only3 subjects(1.1%) had myopia, which was less than or equal to 1.0 D, compared to 70 subjects(29.5%) in the control group, suggesting a statistically significant lower incidence of CSCR among the myopic patients(P <0.0001). With respect to the systemic factors, 26(9.9%)patients were using systemic steroids in the study group(Group 1) compared to none in the control group(Group 2)suggesting a statistically significant association of CSCR with systemic steroid use(P <0.05). No other significant systemic risk factors were noted.· CONCLUSION: Though CSCR is a multifactorial disease, myopia serves as a protective factor for CSCR.Thus, myopic eyes are less likely to develop CSCR.Since both retinal pigment epithelium(RPE) and choriocapillaris are postulated in the pathogenesis of CSCR, chorio-retinal thinning and atrophy seen in myopic eyes are less likely to cause CSCR. | George J.Manayath Saurabh Arora Hardik Parikh Parag K.Shah Sarvesh Tiwari Venkatapathy Narendran | 2016 | International Journal of Ophthalmology(English edition)2016，9，2： | 2 |
| 3 | Clinical profile and outcomes of pediatric endogenous endophthalmitis: A report of 11 cases from South India显示文摘AIM To study the clinical profile and outcomes of pediatric endogenous endophthalmitis from a tertiary eye hospital in South India.METHODS A total of 13 eyes of 11 children presented to us with varied symptoms and presentations of endogenous endophthalmitis, over a five-year period from January 2010 to December 2015 were studied. Except for two eyes of a patient, vitreous aspirates were cultured from all 11 eyes to isolate the causative organism. These eleven eyes also received intravitreal injections. All patients were treated with systemic antibiotics. RESULTS Two cases had bilateral endophthalmitis. Ages ranged from 4 d to 11 years. Five cases were undiagnosed and treated, before being referred to our center. Ten of the 13 eyes underwent a core vitrectomy. The vitrectomy was done at an average on the second day after presenting(range 0-20 d). Five of the 11 vitreous aspirates showed isolates. The incriminating organisms were bacteria in three and fungus in two. An underlying predisposing factor was found in seven patients. At a mean follow-up 21.5 mo, outcome was good in 7 eyes of 6 cases(54%), five eyes of four cases(38%) ended up with phthisis bulbi while one child died of systemic complications. CONCLUSION Endogenous endophthalmitis is a challenge for ophtha-lmologists. Early diagnosis and intervention is the key for a better outcome. | Gayatri Murugan Parag K Shah Venkatapathy Narendran | 2016 | World Journal of Clinical Pediatrics2016，5，4： | 2 |
| 4 | Design and implementation of a low power ternary full adder显示文摘 | SRIVASTAVA A VENKATAPATHY K | 1996 | VLSIDesign1996，4，1： | 1 |
| 5 | Kinetics models for trichloroethylene transformation by zero- valent iron显示文摘 | VENKATAPATHY R BESSINGPAS D G CANONICA S | 2002 | Applied Catalysis B: Environmental2002，37，2： | 1 |
| 6 | Hypersonic single expansion ramp nozzle simulations 显示文摘 | Ruffin S M Venkatapathy E Keener E R | 1992 | Journal of Spacecraft and Rockets1992，29，2： | 1 |
| 7 | Hyperson- ic single expansion ramp nozzle simulations显示文摘 | Ruffin S M Venkatapathy E Keener E R | 1992 | Journal of Spacecraft and Rockets1992，29，2： | 1 |
| 8 | Kinetics models for triehloroethylene transformation by zero-valent iron 显示文摘 | Venkatapathy R Bessingpas D G Canonica S | 2002 | Applied Catalysis B2002，37，2： | 1 |
| 9 | Thermal Protection System Technology and Facility Needs for Demanding Furore Planetary Missions显示文摘 | Laub B Venkatapathy E | 2003 | Trajectory Analysis and Science2003，，10： | 1 |
| 10 | Salivary creatinine estimation as an alternative to serum creati-nine in chronic kidney disease patients 显示文摘 | VENKATAPATHY R GOVINDARAJAN V OZAN | 2014 | Int J Nephrol2014，2014，74： | 1 |
| 11 | Current grid-generation strategies and future requirements in hypersonic vehicle design,analysis and testing显示文摘 | Papadopoulos P Venkatapathy E Prabhu D | 1999 | Applied Mathematical Modelling1999，23，9： | 1 |
| 12 | Kinetics Models for Trichloroethylene Transformation by Zero-valent Iron显示文摘 | Venkatapathy R Bessingpas D C Canonica S Perlinger J A | 2002 | Applied Catalysis B:Environmental2002，37，2： | 1 |
| 13 | Hypersonic Single Expansion Ramp Nozzle Simulations显示文摘 | Ruffin S M Venkatapathy E Keener E R | | 0，，02： | 1 |
| 14 | Application of QSTRs in the selection of a surrogate toxicity value for a chemical of concern 显示文摘 | Moudgal C J Venkatapathy R Choudhury H | 2003 | Environ Sci Technol2003，37，22： | 1 |
| 15 | Relative compositionality of multi-word expressions:a study of Verb-Noun (V-N) collocations显示文摘 | VENKATAPATHY S JOSHI A K | 2005 | Natural Language Processing-IJCNLP 2005 Lecture Notes in Computer Science2005，3651，： | 1 |
| 16 | The Indian retinopathy of prematurity society:a baby step towards tackling the retinopathy of prematurity epidemic in India显示文摘Background:India leads all nations in the number of preterms born annually.With over 3.5 million infants,a reducing infant mortality rate and an expanding base of rural neonatal intensive care units,the number of infants requiring retinopathy of prematurity(ROP)screening has dramatically increased.The number of ROP specialists in the country is currently inadequate.Leading ROP specialists of the country initiated the Indian ROP(IROP)society to address these challenges.Methods:In 2016,the IROP society was conceived and registered as a professional body with a mission to prevent needless blindness from ROP by promoting standards of excellence.A national online membership drive was carried out.The data collected in this survey was analyzed to collate information on past training,practice patterns,ease of screening and treatment,use of wide-field imaging and willingness to be certified.Results:Of the 113 members at the time of submission,67.3%were male.88.5%were formally trained for ROP and 85.8%were vitreo-retinal specialists.Of the practicing members,96%were“comfortable”with screening and 86%with ROP treatment and this correlated with training(P=0.001 and P=0.002 respectively).Only 25.7%performed vitreous surgery for ROP.Wide field imaging was used by 33%of members in their practice and 52%of those who did not,wanted to use it in the future.Members who used imaging performed more number of laser treatments than those who did not(P=0.008).Laser was the preferred modality of treatment for 98%of members.A majority of the members(92.5%)were willing to be audited.Conclusions:The IROP society is a novel platform for ROP specialists to collaborate.The society has setup short,mid and long-term goals to make ROP care more accessible and affordable with appropriate use of technology. | Anand Vinekar Rajvardhan Azad Mangat Ram Dogra Venkatapathy Narendran Subhadra Jalali Pramod Bende | 2017 | Annals of Eye Science2017，，1： | 1 |
| 17 | Kinetics Models for Trichloroethylene Transformation by Zero-valent Iron 显示文摘 | VENKATAPATHY R BESSINGPAS D G CANONIEA S et ol | 2002 | Applied Catalysis B: Environmental2002，37，： | 1 |
| 18 | Are the chemical structures in your QSAR correct? 显示文摘 | Young D Martin T Venkatapathy R | 2008 | QSAR Comb Sci2008，27，1112： | 1 |
| 19 | Assessment of the oral rat chronic lowest observed adverse effect level model in TOPKAT,a QSAR software package for toxicity prediction显示文摘 | Moudgal CJ Bruce RM | 2004 | J Chem Inf Comput Sci2004，44，： | 1 |
| 20 | Assess- ment of the oral rat chronic lowest observed adverse effect level model in TOPKAT,a QSAR software package for toxicity predic- tion显示文摘 | VENKATAPATHY R MOUDGAL C J BRUCE R M | 2004 | Journal of chemical information and computer sciences2004，44，5： | 1 |
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