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| 1 | Genes associated with testicular germ cell tumors and testicular dysgenesis in patients with testicular microlithiasis显示文摘阴囊的 microlithiasis (TM ) 是阴囊的 dysgenesis 症候群(TDS ) 的症状之一。TM 作为阴囊的细菌房间肿瘤(TGCT ) 的一个增进知识的标记特别地有趣。工具包 ligand 基因( KITLG ), BCL2 对手/杀手 1 ( BAK1 ),并且表明对手 4 的 sprouty RTK ( SPRY4 ),基因与 TGCT 的高风险被联系骨头形态基因的蛋白质 7 基因( BMP7 ),转变生长因素贝它受体 3 基因( TGFBR3 ),并且 homeobox D 簇基因( HOXD )与 TDS 有关。使用的聚合酶链反应限制碎片长度多型性( PCR-RFLP )分析,我们为 KITLG 调查了等位基因和遗传型频率( rs995030 , rs1508595 ), SPRY4 ( rs4624820 , rs6897876 ), BAK1 ( rs210138 ), BMP7 ( rs388286 ), TGFBR3 ( rs12082710 ),并且在 142 个 TGCT 病人, 137 个 TM 病人,和 153 个肥沃的人(控制组)的 HOXD ( rs17198432 )。我们在 TM 在 KITLG GG_rs995030 遗传型发现了重要差别(P = 0.01 ) 并且 TGCT 病人(P = 0.0005 ) 与控制相比。我们也揭示了在 KITLG_rs1508595 和 TM 之间的强壮的协会(G 等位基因, P = 0.003;GG 遗传型, P = 0.01 ) 并且在 KITLG_rs1508595 和 TGCT 之间(G 等位基因, P = 0.0001;GG 遗传型, P = 0.0007 ) 。而且,在在 TGCT 组和控制之间的 BMP7_rs388286 有重要差别(T 等位基因, P = 0.00004;TT 遗传型, P = 0.00006 ) 并且在 TM 组和控制之间(T 等位基因, P = 0.04 ) 。HOXD 也与 TGCT 表明了一个强壮的协会(rs17198432 A 等位基因, P = 0.0001;AA 遗传型, P = 0.001 ) 。而且,重要差别在 BAK1_rs210138 G 等位基因在 TGCT 组和控制之间被发现(P = 0.03 ) 并且 GG 遗传型(P = 0.01 ) 。KITLG 和 BMP7 基因,与 TGCT 的发展联系了,可能也与 TM 有关。在摘要, KITLG GG_rs995030, GG_rs1508595, BMP7 TT_rs388286, HOXD AA_rs17198432,和 BAK1 GG_rs210138,遗传型与 TGCT 开发的高风险被联系。 | Ilya S Dantsev Evgeniy V Ivkin Aleksey A Tryakin Dmitriy N Godlevski Oleg Yu Latyshev Victoriya V Rudenko Dmitry S Mikhaylenko Vyacheslav B Chernykh Elena A Volodko Aleksey B Okulov Oleg B Loran Marina V Nemtsova | 2018 | Asian Journal of Andrology2018，20，6： | 4 |
| 2 | Phytochemical Analysis and Antioxidant Activity of Crocus speciosus Leaves显示文摘The numerous studies indicate leaves of plants are a rich source of bioactive compounds that can be a valuable source of compounds used in the pharmaceutical and cosmetic industries.Aim of this study was to investigate the chemical composition and the antioxidant property of Crocus speciosus leaves.Primary phytochemical screening of C.speciosus leaves revealed the presence of some following compound categories such as phenolic compounds,aminoacids,saponins,proteins,tannins,triterpenoids,glycosides,polysaccharides.The total flavonoids and phenolic compounds content were determined spectrophotometrically and by HPLC-DAD and HPLC-MS.Antiradical activity was determined by ABTS radical-cation scavenging method,spectrophotometrically.The total amount of flavonoids in C.speciosus leaves was 1.07±0.02 mg RE/g(p<0.05),the total amount of phenolic compounds was 0.41±0.01 mg GAE/g(p<0.05).By HPLC-DAD-MS analysis the presence of the mangiferin,chlorogenic acid,isoorientin,kaempferol,hyperoside,and isoquercitin was established for the first time in Crocus leaves.The antiradical activity of C.speciosus leaves extracts was 150.08±4.5μmol/g(p<0.05)and its was mainly attributed to phenolic compounds content.The high amounts of flavonoids and antiradical activity in C.speciosus leaves suggests promising phytochemical and pharmacological study of this Crocus species. | Olha Mykhailenko Ivan Bezruk Victoriia Volochai Volodymyr Mishchenko Liudas Ivanauskas Victoriya Georgiyants | 2022 | Phyton-International Journal of Experimental Botany2022，91，1： | 1 |
| 3 | Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer显示文摘 | Konstantinos K. Tsilidis Kathy J. Helzlsouer Michael W. Smith Victoriya Grinberg Judith Hoffman-Bolton Sandra L. Clipp Kala Visvanathan Elizabeth A. Platz | 2009 | Cancer Causes & Control2009，，9： | 1 |
| 4 | Depende- nce of complex alloyed steel pnpertieson quenching and tempering conditions显示文摘 | Vinokur Bertold B Vinokur Alexandr Shtessel Victoriya E | 1996 | Metallurgical and Materials Transactions1996，，9： | 1 |
| 5 | The dependence of complex alloyed steel properties on quenching and tempering conditions显示文摘 | Bertold B. Vinokur Alexandr Vinokur Victoriya E. Shtessel | 1996 | Metallurgical and Materials Transactions A1996，，9： | 1 |
| 6 | Analysis of Calcium and Phosphorus in Pregnant Women’s Oral Fluid in the Republic of Belarus显示文摘A change of the saliva biochemical components during pregnancy affects on enamel and it’s resistance to microorganisms of the oral cavity.It is necessary to prevent an increase of pathological processes.Determining the concentration of calcium and inorganic phosphorus in oral liquid by photometry is the rational method of mineralization potential.The concentration of calcium and phosphorus in pregnant women’s oral fluid was not measured in the republic of Belarus nor compared with standard indicators.In this case,we should take appropriate actions related with calcium and inorganic phosphorus concentration in oral fluid of pregnant women to avoid oral diseases such as caries and sanitize oral cavity in time. | Butvilovsky Alexsander Bulatova Victoriya Volchok Anastasia Huzei Iryna | 2019 | Journal of Pharmacy and Pharmacology2019，7，12： | 1 |
| 7 | Early prophylaxis of preeclampsia in women at risk for changes in spiral arteries显示文摘【Objective】 To investigate the possibility of early prophylaxis of preeclampsia by mean of investigation of uteroplacental blood flow(UPB) and feto-placental complex FPC function in pregnant women with suspected dysfunction of spiral arteries and clinical signs of preeclampsia.【Method】 90 pregnant women were included in a prospective cohort study in the term of gestation from 9 to 40 weeks.The main clinical group consisted of 70 women,divided into two groups: the first-pregnant with the risk of PE,the others-with the clinical manifestation of PE.Biochemical and radioimmunoassay studies(determination of estradiol and placental lactogen(PL) in the peripheral blood),ultrasound examination with Doppler flow in the arteries of the uterus and the measurement of qualitative characteristics of the analysis of blood flow-resistance index(RI) and pulsatility index(PI),the ratio of systolic pressure for diastolic(ABP) were used.Treatment in the group of risk was directed to the correction of vascular blood flow and intravascular component(antiplatelet agents,antispasmodics,sedatives drugs,vitamins) and was conducted in terms of 9-12 weeks duration during 12-14 days.In the subgroup with PE-similar treatment in terms of 28-30 weeks.【Result】 In pregnant women of the group of risk for PE abnormal spiral artery blood flow parameters(RI,PI,ABP) in the uterine arteries were registered,indicating increased peripheral vascular resistance in the placental pool in early pregnancy,just as marked reduction of the hormonal activity of forming placental complex which testifies early placental insufficiency.Treatment,conducted in early pregnancy could significantly improve,but not normalize blood flow.【Conclusion】 Conduction of a Doppler examination for blood flow of the placenta may provide early diagnose of infusion-perfusion failure of placenta,and the appointment of a pathogenic therapy,that will provide an opportunity to avoid the development of placenta failure and PE in an group of risk. | Nagornaya Victoriya Marichereda Valerie | 2011 | 中国现代医学杂志2011，21，27： | 1 |
| 8 | Features of Obtaining of Polypropylene Microfibers with Nanosize Fillers显示文摘 | Tsebrenko Mariya Vasilyevna Rezanova Victoriya Georgiyevna Tsebrenko Irina Aleksandrovna | 2010 | 材料科学与工程(中英文版)2010，4，6： | 0 |
| 9 | Wildlife forensic examination in Russia:the practice and perspectives显示文摘Two case studies are described which show application of forensic expertise to establish important circumstances related to the investigation of the crimes against wildlife flora and fauna.Forensic study of the animal hair is a method for investigation of the crimes against wildlife objects which is used more frequently during the recent years.The perspectives of development of the new branch of forensic research in Russia are formulated,and the proposals and recommendations for developing the Eurasian wildlife flora and fauna network are formulated in this article. | Svetlana A.Smirnova Georgy G.Omelyanyuk Victoriya V.Gulevskaya Shamil N.Khaziev | 2016 | Forensic Sciences Research2016，1，1： | 0 |
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