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1Role of biosurfactants in bioremediation of oil pollution-a review显示文摘The energy resources mainly petroleum and petroleum hydrocarbons are major pollutants of the environment.The oil and oil products contamination may cause severe harm and hence,the attention has been remunerated in the development of alternative technologies for elimination of these contaminants.Biosurfactants were used in the remediation of oil pollution due to advantages such as biodegradability and low toxicity.The biosurfactants are produced from low cost substrates like agro-industrial wastes which reduce the cost of production.Biosurfactants and bioemulsifiers are amphiphilic compounds and are produced as extracellular or a part of the cell membrane by bacteria.The insight view,how hydrocarbons are degraded by microorganisms and thereby reduce the damage of ecosystem is highly essential to target the problem.Biofilms are the bacterial communities which protects the bacterial cells from various adverse conditions.The present review describes the biosurfactants and its synthesis from bacteria and also emphases on the role of surfactants in oil remediation.Abraham Peele Karlapudi TCVenkateswarulu Jahnavi Tammineedi Lohit Kanumuri Bharath Kumar Ravuru Vijaya ramu Dirisala Vidya Prabhakar Kodali 2018Petroleum2018,4,3:13
2Thymoquinone suppresses migration of Lo Vo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation显示文摘AIM To identify potential anti-cancer constituents in natural extracts that inhibit cancer cell growth and migration.METHODS Our experiments used high dose thymoquinone(TQ) as an inhibitor to arrest Lo Vo(a human colon adenocarcinoma cell line) cancer cell growth, which was detected by cell proliferation assay and immunoblotting assay. Low dose TQ did not significantly reduce Lo Vo cancer cell growth. Cyclooxygenase 2(COX-2) is an enzyme that is involved in the conversion of arachidonic acid into prostaglandin E2(PGE2) in humans. PGE2 can promote COX-2 protein expression and tumor cell proliferation and was used as a control.RESULTS Our results showed that 20 μmol/L TQ significantly reduced human LoV o colon cancer cell proliferation. TQ treatment reduced the levels of p-PI3 K, p-Akt, p-GSK3β, and β-catenin and thereby inhibited the downstream COX-2 expression. Results also showed that the reduction in COX-2 expression resulted in a reduction in PGE2 levels and the suppression of EP2 and EP4 activation. Further analysis showed that TG treatment inhibited the nuclear translocation of β-catenin in LoV o cancer cells. The levels of the cofactors LEF-1 and TCF-4 were also decreased in the nucleus following TQ treatment in a dose-dependent manner. Treatment with low dose TQ inhibited the COX-2 expression at the transcriptional level and the regulation of COX-2 expression efficiently reduced LoV o cell migration. The results were further verified in vivo by confirming the effects of TQ and/or PGE2 using tumor xenografts in nude mice.CONCLUSION TQ inhibits LoV o cancer cell growth and migration, and this result highlights the therapeutic advantage of using TQ in combination therapy against colorectal cancer.Hsi-Hsien Hsu Ming-Cheng Chen Cecilia Hsuan Day Yueh-Min Lin Shin-Yi Li Chuan-Chou Tu Viswanadha Vijaya Padma Hui-Nung Shih Wei-Wen Kuo Chih-Yang Huang 2017World Journal of Gastroenterology2017,23,7:12
3Effect of quercetin against lindane induced alterations in the serum and hepatic tissue lipids in wistar rats显示文摘Objective:To assess the effect of quercetin(flavonoid) against lindane induced alterations in lipid profile of wistar rats.Methods:Rats were administered orally with lindane(100 mg/kg body weight) and quercetin(10 mg/kg body weight) for 30 days.After the end of treatment period lipid profile was estimated in serum and tissue.Results:Elevated levels of serum cholesterol, triglycerides,low density lipoprotein(LDL),very Low Density Lipoprotein(VLDL) and tissue triglycerides,cholesterol with concomitant decrease in serum HDL and tissue phospholipids were decreased in lindane treated rats were found to be significantly decreased in the quercetin and lindane co-treated rats.Conclusions:Our study suggests that quercetin has hypolipidemic effect and offers protection against lindane induced toxicity in liver by restoring the altered levels of lipids.The quercetin cotreatment along with lindane for 30 days reversed these biochemical alterations in lipids induced by lindane.Viswanadha Vijaya Padma Gurusamy Lalitha Nichokon Puthanveedu Shirony Rathinasamy Baskaran 2012Asian Pacific Journal of Tropical Biomedicine2012,2,11:9
4ACS Nano:科学家利用来自尿液的生物标志物进行早期癌症筛查显示文摘日前。来自韩国蔚山国家科学技术研究所的研究人员通过研究开发出了一种新技术,该技术能够有效在尿液或血液中有效鉴别出促进癌症发生的物质,相关研究刊登于国际杂志ACS Nano上。Hyun-Kyung Woo Vijaya Sunkara Juhee Park Tae-Hyeong Kim Ja-Ryoung Han Chi-Ju Kim Hyun-Il Choi Yoon-Keun Kim Yoon-Kyoung Cho 2017现代生物医学进展2017,17,11:8
5Pure and Mg-doped self-assembled ZnO nano-particles for the enhanced photocatalytic degradation of 4-chlorophenol显示文摘A novel self-assembled pure and Mg doped ZnO nano-particles(NPs) were successfully synthesized by a simple low temperature co-precipitation method. The prepared photocatalysts were characterized by X-ray difraction, high resolution scanning electron microscopy, high resolution transmission electron microscopy, difuse reflectance spectroscopy and photoluminescence(PL) spectroscopy.The results indicated that the prepared photocatalysts showed high crystallinity with a uniform size distribution of the NPS. The degradation of cholorphenols is highly mandatory in today's scenario as they are afecting the environment adversely. Thus, the photocatalytic degradation of 4-chlorophenol(4-CP), a potent endocrine disrupting chemical in aqueous medium was investigated by both pure and Mg-doped ZnO NPs under UV-light irradiation in the present study. The influence of the Mg content on the structure,morphology, PL character and photocatalytic activity of ZnO NPs were investigated systematically. Furthermore,the efect of diferent parameters such as 4-CP concentration, photocatalyst amount, pH and UV-light wavelength on the resulting photocatalytic activity was investigated.N.Clament Sagaya Selvam S.Narayanan L.John Kennedy J.Judith Vijaya 2013Journal of Environmental Sciences2013,25,10:8
6Simultaneous determination of pioglitazone and candesartan in human plasma by LC-MS/MS and its application to a human pharmacokinetic study显示文摘A simple and rapid liquid chromatography-tandem mass spectrometric(LC-MS/MS) assay method has been developed and fully validated for simultaneous quantification of pioglitazone and candesartan in human plasma.Irbesartan was used as an internal standard.The analytes were extracted from human plasma samples by solid-phase extraction technique using a Strata-X 33 mm polymeric sorbent.The reconstituted samples were chromatographed on a C18 column by using a 80:20(v/v) mixture of acetonitrile and 0.1% formic acid as the mobile phase at a flow rate of 0.8 mL/min.The calibration curves obtained were linear(rZ0.99) over the concentration range of 15-3000 ng/mL for pioglitazone and 5-608 ng/mL for candesartan.The results of the intra-and inter-day precision and accuracy studies were well within the acceptable limits.A run time of 2.7 min for each sample made it possible to analyze more than 300 plasma samples per day.The proposed method was found to be applicable to clinical studies.Vijaya Kumari Karra Nageswara Rao Pilli Jaswanth Kumar Inamadugu J.V.L.N.Seshagiri Rao 2012Journal of Pharmaceutical Analysis2012,2,3:8
7Investigation of hepatoprotective activity of Cyathea gigantea(Wall.ex.Hook.)leaves against paracetamol-induced hepatotoxicity in rats显示文摘Objective:To investigate the hepatoprotective activity of methanolic leaf extract of Cyathea gigantea(C.gigantea)against paracetamol induced liver damage in rats.Methods:The hepatoprotective activity for plant extract was investigated for paracetamol induced hepatoxicity in rats.Wislar albino rats of either sex were divided into five groups of 6 animals each and are given orally the following treatment for seven days.The normal control group was given 1%Na.CMC 1mL/kg bw,p.o.Paracetamol at dose of 1g/kg bw,p.o.was given as toxic dose for inducing hepatoloxicity.Silymarin(50mg/kg.p.o.) was given as reference standard.Two doses of C. gigantea extract i.e.,100 mg/kg.p.o.and 200 mg/kg,p.o.were tested for hepatoprotective activity. The treatment was given for seven days and after 24 h of last treatment blood was collected from retro-orbital plexus and analysed for various serum parameters like serum glutamic-oxaloacetic transaminase(SGOT),serum glutamic pyruvic transaminase(SGPT),alkaline phosphatase(ALP),total bilirubin(TB)and total protein(TP)in different groups.Results:The paracetamol intoxication lead to histological and biochemical deteriorations.The treatment with methanolic leaf extract of C.gigantea reduced the elevated levels of SCOT,SGPT,ALP,TB and also reversed the hepatic damage towards normal which further supports the hepatoprotective activity of leaf extract of C.gigantea.Conclusions:The methanolic extract of leaves of C.gigantea at doses of 100 mg/kg bw and 200 mg/kg bw have significant effect on liver of paracetamol induced hepatotoxicity model in rats.P Madhu Kiran A Vijaya Raju B Ganga Rao 2012Asian Pacific Journal of Tropical Biomedicine2012,2,5:7
8Flotation studies on low grade graphite ore from eastern India显示文摘A low grade graphite ore from eastern India was beneficiated by flotation to improve its quality. The ore was composed of 87.80% ash and 8.59% fixed carbon. Primary coarse wet grinding(d80: 186 lm) followed by rougher flotation in Denver flotation cell using diesel as collector and pine oil as frother yielded a rougher concentrate. Regrinding(d80: 144 lm) of this rougher concentrate was opted for further liberation of graphite. It was followed by cleaning in laboratory flotation column. This combined process of relatively coarse primary grinding followed by regrinding and cleaning in flotation column resulted in final concentrate of 7.44% yield with 89.65% fixed carbon and 6.00% ash. This approach of two-stage grinding to recover the flake graphite at the coarsest possible grind can help to minimize grinding energy costs. A conceptual flow sheet which is cost effective was developed based on this methodology.Vasumathi N. Vijaya Kumar T.V. Ratchambigai S. Subba Rao S. Bhaskar Raju G. 2015International Journal of Mining Science and Technology2015,25,3:6
9氧化锌-氧化铜纳米复合物可见光诱导光催化降解2,4-二氯酚性能(英文)显示文摘Nanostructured ZnO and CuO, and coupled oxides, i.e., ZnCu, Zn2Cu, and ZnCu2, with ZnO:CuO molar ratios of 1:1, 2:1, and 1:2, respectively, were successfully prepared through a simple, one-step, microwave-assisted urea–nitrate combustion synthesis, without the use of organic solvents or surfactants. The prepared samples were characterized using X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy, energy-dispersive X-ray analysis, transmission electron microscopy, Fourier-transform infrared spectroscopy, diffuse reflectance spectroscopy, and photoluminescence spectroscopy. The optical absorption of Zn O extended into the visible region after CuO loading. The photocatalytic activities of ZnO, CuO, and the coupled oxides were evaluated based on photodegradation of 2,4-dichlorophenol under visible-light irradiation. The coupled metal oxide Zn2Cu showed the best photocatalytic activity; this was mainly attributed to the extended photoresponsive range and the increased charge separation rate in the nanocomposite. The photocatalytic degradation process obeyed pseudo-first-order kinetics. The results suggest that the coupled metal oxide Zn2Cu has potential applications as an efficient catalytic material with high efficiency and recyclability for the photocatalytic degradation of organic pollutants in aqueous solution under visible-light irradiation.E.D.Sherly J.Judith Vijaya L.John Kennedy 2015催化学报2015,36,8:5
10Beneficiation of an Indian non-coking coal by column flotation显示文摘N. Vasumathi T. V. Vijaya Kumar S. Ratchambigai S. Subba Rao S. Prabhakar G. Bhaskar Raju 2016International Journal of Coal Science & Technology2016,3,2:5
11微波合成Zr-AC,Ni-AC和Zn-AC光催化降解印染废水(英文)显示文摘采用微波照射法成功制备新型氧化锆、氧化镍和氧化锌负载活性炭纳米颗粒。采用XRD、HR-SEM和BET对合成纳米颗粒进行表征。利用UV-Vis漫反射光谱法研究Zr-AC、Ni-AC和Zn-AC复合材料的光学性能。验证了紫外光照射下印染废水的光催化效率。每隔一定时间观察印染废水的化学需氧量,以计算化学需氧量的去除率。结果表明,Zn-AC复合材料具有明显的光催化性,这归因于紫外光区域吸光度的增大、染料分子的有效吸附能力、辅助电荷转移和电子-空穴对抑制重组。利用Zn-AC复合材料降解印染废水可以得到最大的降解率(82%化学需氧量去除率)。在Zn-AC复合材料表面设计一个可能实现的协同机制。Zn-AC复合材料重复使用5次后,其催化活性无明显降低。P.SURESH J.JUDITH VIJAYA L.JOHN KENNEDY 2015Transactions of Nonferrous Metals Society of China2015,25,12:4
12Coumarin-derived azolyl ethanols:synthesis,antimicrobial evaluation and preliminary action mechanism显示文摘A series of coumarin-derived azolyl ethanols including imidazolyl,triazolyl,tetrazolyl,benzotriazolyl,thiol-imidazolyl and thiol-triazolyl ones were conveniently synthesized and characterized by IR,~1H NMR,^(13)C NMR and high-resolution mass spectra(HRMS) spectra.Some of the prepared compounds showed appropriate logP_(ow) values and effective antibacterial and antifungal activities.Noticeably,compound 14 with bis-triazolyl ethanol group exhibited low minimal inhibitory concentration(MIC)value of 8 μg/mL against MRSA,which was comparable or even superior to reference drugs Norfloxacin(MIC=8μg/mL)and Chloramphenicol(MIC=16μg/mL).It could also effectively inhibit the growth of the tested fungal strains compared to Fluconazole.Further binding studies of coumarin 14 with calf thymus DNA were investigated by UV-Vis absorption and fluorescence spectroscopy.It was found that compound 14 could interact with calf thymus DNA by groove binding to form14-DNA complex via both hydrogen bonds and van der Waals force,which might be the factor to exert the powerful antimicrobial activity.Xin-Mei Peng Kannekanti Vijaya Kumar Guri L.V. Damu Cheng-He Zhou 2016Science China Chemistry2016,59,7:4
13快速微波燃烧法制备的Cu-Ni合金纳米粒子结构和磁性能(英文)显示文摘采用微波燃烧法制备Cu2+和Ni2+摩尔比分别为3∶7,4∶6,5∶5,6∶4和7∶3的Cu-Ni合金纳米粒子,采用XRD、HR-SEM、EDX和VSM对所制备的样品进行表征.X射线衍射和能谱分析表明,在样品制备过程中形成了纯合金粉末.样品的平均晶粒尺寸为21.56~33.25 nm.HR-SEM像显示样品具有集群/团簇粒状形态结构.VSM分析结果表明,对于低Ni含量的合金(Cu5Ni5,Cu6Ni4和Cu7Ni3),样品显示顺磁性,而对于较高Ni含量的合金(Cu3Ni7和Cu4Ni6),样品呈现铁磁性.J.ARUL MARY A.MANIKANDAN L.JOHN KENNEDY M.BOUOUDINA R.SUNDARAM J.JUDITH VIJAYA 2014Transactions of Nonferrous Metals Society of China2014,24,5:4
14铁苋菜叶提取物抑制大鼠实验性心肌缺血的生物化学和组织病理学研究(英文)显示文摘目的:研究富含类黄酮的热带铁苋菜叶的甲醇提取物抗心肌缺血的作用。方法:用异丙肾上腺素诱导大鼠心肌缺血。成年Wistar白化大鼠经热带铁苋菜提取物(100和200mg/kg大鼠体质量,口服)30d预处理后连续2d注射异丙肾上腺素(85mg/kg大鼠体质量,皮下注射)。第2次注射异丙肾上腺素后12h,肌肉注射氯胺酮(24mg/kg大鼠体质量)处死大鼠。检测血浆总胆固醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、极低密度脂蛋白胆固醇、游离脂肪酸、磷脂质以及心肌脂质、肝脏脂质的含量,以衡量热带铁苋菜提取物的抗心肌缺血作用,同时观察大鼠心脏组织的组织病理学变化。结果:与模型组大鼠相比,所有热带铁苋菜提取物给药组(100和200mg/kg)大鼠的血浆脂质水平改善,且与正常组相比无明显变化。模型组大鼠心脏组织病理学结果显示心肌纤维缺失,广泛性心内膜下坏死,炎症细胞浸润,心肌细胞明显水肿,空泡变性。而经200mg/kg热带铁苋菜提取物预处理的大鼠心脏组织观察到较完整的心肌结构,心肌纤维可见,没有炎症细胞浸润、细胞水肿和坏死现象。结论:本研究的生化指标及组织学结果表明热带铁苋菜可抑制异丙肾上腺素诱导的大鼠心肌缺血。Kalla C.Mouli Tartte Vijaya Sirpurkar Dattatreya Rao 2012中西医结合学报2012,10,7:3
15离子选择电极阵列测定土壤中硝态氮显示文摘土壤硝态氮反映土壤短期氮素供应水平,实时了解土壤硝态氮的含量为精准农业和农业面源污染防控提供支撑,因此,在线实时检测土壤硝态氮方法突破就显得十分迫切。土壤硝态氮中的硝酸根离子在土壤中的高水溶性和流动性为全固态硝酸根离子选择电极高敏感检测土壤中硝态氮提供了条件,固态硝态氮离子选择电极的离子选择膜反应硝酸根离子在被测溶液中的浓度。采用全固态硝酸根离子选择电极ELIT NO_(3)^(-),且与温度电极和pH电极融合组成电极阵列对土壤饱和溶液中的硝酸根离子进行检测。设计了高输入阻抗运算放大电路对电极信号进行采集,并通过微处理控制蠕动泵完成土壤硝态氮待测溶液连续流动测定及实时传输结果。实验结果表明,电极响应时间≤15 s,斜率-51.63 mV/decade,线性范围10^(-5)~10^(-2.2) mol/L,最低检测限10^(-5.23) mol/L。相对标准差在0.78%~4.5%,加标回收率均在90.0%~110%。与紫外可见分光光度法测试结果相比,相关系数(R^(2))为0.9952,为土壤硝态氮在现场检测奠定技术基础。苏睿 苑锋 吴俊锋 位文涛 VIJAYA Raghavan 胡建东 2022中国无机分析化学2022,12,1:3
16Analytics,challenges and applications in big data environment:a survey显示文摘Big data refer to the massive amounts and varieties of information in the structured and unstructured form,generated by social networking sites,biomedical equipment,financial companies,internet and websites,scientific sensors,agriculture engineering sources,and so on.This huge amount of data cannot be processed using traditional data processing systems and technologies.Big data analytics is a process of examining information and patterns from huge data.Hence,the process needs a system architecture for data collection,transmission,storage,processing and analysis,and visualization mechanisms.In this paper,we review the background and futuristic aspects of big data.We first introduce the history,background and related technologies of big data.We focus on big data system architecture,phases and classes of big data analytics.Then we present an open source big data framework to address some of the big data challenges.Finally,we discuss different applications of big data with some examples.Mininath R.Bendre Vijaya R.Thool 2016Journal of Management Analytics2016,3,3:3
17Two-Dimensional Photonic Crystal Based Sensor for Pressure Sensing显示文摘在这份报纸,二维的 photonic 晶体(2DPC ) 基于压力传感器被建议并且设计,并且象敏感那样的察觉到的特征和动态范围从 0 GPa 在压力的范围上被分析到 7 GPa。传感器与坐飞机包围的硅杆的方形的数组基于 2DPC。传感器由二 photonic 水晶伪波导和 L3 缺点组成。L3 缺点被放在二波导之间并且被修改三 Si 杆的半径形成。当增加应用压力水平时,通过模拟,传感器的反响的波长向更高的波长区域线性地被转移,这被注意当增加应用压力水平时。完成的敏感和传感器的动态范围分别地是 2 nm/GPa 和 7 Gpa。Krishnan VIJAYA SHANTHI Savarimuthu ROBINSON 2014Photonic Sensors2014,4,3:3
18Starch based nanofibrous scaffolds for wound healing applications显示文摘Starch is an attractive polymer for wound healing applications because of its wide availability,low cost,biocompatibility,biodegradability and wound-healing property.Here,we have fabricated starch-based nanofibrous scaffolds by electrospinning for wound healing applications.The diameter of the optimized nanofibers was determined by field emission scanning electron microscopy(FE-SEM)and was found to be in the range of 110e300 nm.The mechanical strength(0.5e0.8 MPa)of the nanofibrous scaffolds was attuned using polyvinyl alcohol(plasticizer)and glutaraldehyde(crosslinking agent),to impart them with sufficient durability for skin tissue engineering.Absence of negative interactions between the polymers was confirmed by Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy(ATR-FTIR),differential scanning microscopy(DSC)and thermal gravimetric analysis(TGA).Cellular assays with L929 mouse fibroblast cells indicated the ability of the scaffolds to promote cellular proliferation,without exhibiting any toxic effect to the cells.Thus,the nanofibrous scaffolds demonstrated potential for wound healing applications.Vijaya Sadashiv Waghmare Pallavi Ravindra Wadke Sathish Dyawanapelly Aparna Deshpande Ratnesh Jain Prajakta Dandekar 2018Bioactive Materials2018,3,3:3
19S-,N-and C-doped ZnO as semiconductor photocatalysts:A review显示文摘In the past few decades,many novel non-metal doped ZnO materials have developed hasty interest due to their adaptable properties such as low recombination rate and high activity under the solar light exposure.In this article,we compiled recent research advances in non-metal(S,N,C)doped ZnO,emphasizing on the related mechanism of catalysis and the effect of non-metals on structural,morphological,optical and photocatalytic characteristics of ZnO.This review will enhance the knowledge about the advancement in ZnO and will help in synthesizing new ZnO-based materials with modified structural and photocatalytic properties.Vijaya KUMARI Anuj MITTAL Jitender JINDAL Suprabha YADAV Naveen KUMAR 2019Frontiers of Materials Science2019,13,1:3
20Follow-up of Primary Angle Closure Suspects After Laser Peripheral Iridotomy Using Ultrasound Biomicroscopy and A-Scan Biometry for a Period of 2 Years显示文摘Krishna Kumar Ramani Baskaran Mani Ronnie J. George Vijaya Lingam 2009Journal of Glaucoma2009,,7:2
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