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| 1 | Isolation and characterization of halophilic Bacillus sp.BS3 able to produce pharmacologically important biosurfactants显示文摘Objective:To characterize the pharmacological importance of biosurfactants isolated from halophilic Bacillus sp BS3.Methods:Halophilic Bacillus sp.BS3 was isolated from solar salt works,identified by 16S rRNA sequencing and was used for screening their biosurfactant production.Characters of the biosurfactant and their anticancer activity were analyzed and performed in mammary epithelial carcinoma cell at different concentrations.Results:The biosurfactant were characterized by TLC,FTIR and GC-MS analysis and identified as lipopeptide type.GC-MS analysis revealed that,the biosurfactant had various compounds including 13Docosenamide.(Z);Mannosamine,9- and N,N,N',N'-tetramethyl.Surprisingly the antiviral activity was found against shrimp white spot syndrome virus(WSSV) by suppressing the viral replication and significantly raised shrimp survival(P<0.01).Anticancer activity performed in the mammary epithelial carcinoma cell at different concentrations of biosurfactants,among the various concentrations of biosurfactants such as 0.000 25,0.002 5,0.025,0.25 and 2.5 μ g,the 0.25 μ g concentration suppressed the cells significantly(P<0.05) to 24.8%.Conclusions:Based on the findings,the present study concluded that,there is a possibility to develop eco-friendly antimicrobial and anticancer drugs from the extremophilic origin. | MBS Donio SFA Ronica V Thanga Viji S Velmurugan J Adlin Jenifer M Michaelbabu T Citarasu | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，11： | 5 |
| 2 | Biosecurity risk mapping and gap analysis in South East Asia显示文摘Introduction:In today’s globalized world where travel is commonplace,a threat in one region can easily spread throughout the whole world.It is,therefore,essential for multi-disciplinary risk assessment,risk mitigation,and collaborative strategies to take place among various stakeholders to mitigate this.Any strategic plan to deal with biosecurity,therefore,needs to be a complete loop,top to bottom and bottom to top.This paper describes the results of Project 62,which involved mapping and biosecurity risk assessment in South East Asia.Materials and methods:The mapping and biosecurity risk assessment activities for the participating partner countries was carried out in two phases.The first phase involved risk assessment by six partnercountry bio-experts for their own countries and the second phase involved conducting a joint Strengths,Weaknesses,Opportunities,and Threats(SWOT)analysis and risk assessment for the South East Asian region as whole,together with international bio-experts at a workshop.Results and discussion:The following key recommendations of the project show that biosecurity needs to be addressed through stakeholder engagement at multiple levels starting from the top echelons of the government to the worker who needs to recognize and understand the threats they might face:1.Systematic analysis of existing information from BWC ISU Article 10,IHR capacities,JEE,UN Security Council Resolution 1540 Action Plan,EU CBRN NAP,and other relevant sources to develop a common understanding of the definition of biosecurity for all stakeholders in the region.2.Creation of programs for awareness building in biosecurity,not limiting them to laboratory biosecurity but using an all-inclusive approach to include border biosecurity,pandemic response,etc.3.Creation of a country-specific list of high-risk biological materials.4.Compulsory standardized biosecurity training,including responsible conduct in biosecurity research.5.Framework for one-health and security interface addressing biosecurity threats.6.Framework for ensuring information security in relation to biosecurity.7.Involvement of local/regional experts in the implementation of EU-CBRN CoE projects. | Emily Valentin Castriciones Viji Vijayan | 2020 | Journal of Biosafety and Biosecurity2020，2，1： | 2 |
| 3 | Modulation of an- giogenic factors by ursolic acid 显示文摘 | Kiran MS Viji RI Sameer Kumar VB | 2008 | Biochem Biophys Res Com- mun2008，371，3： | 1 |
| 4 | Genetic diversity of Sclerotinia homoeocarpa isolates from turfgrasses from various regions in north America显示文摘 | Viji G Uddin W O'Neill N R | 2004 | Plant Disease2004，88，11： | 1 |
| 5 | A temperature and leaf wetness suring-based model for prediction of gray leaf spot of perennial ryegrass turf显示文摘 | Uddin W Serlemitsos K Viji G 2003 | 2003 | Phytopathology2003，93，： | 1 |
| 6 | Modulation of angio- genic factors by ursolic acid显示文摘 | Kiran MS Viji RI Sameer Kumar VB | 2008 | Biochem Biophys Res Commun2008，371，3： | 1 |
| 7 | Anti-ulcer activity of Ficus religiosa leaf ethanolic extract显示文摘Objective:To evaluate the anti-ulcer activity and acute toxicity ofFicus religiosa(F. religiosa)leaf ethanolic extract in animal models.Methods:Anti-ulcer activity ofF. religiosaethanolicextract(250 and 500 mg/kg body weight) was studied on stress induced ulcer animal models.Ranitidine was used as standard. The anti-ulcer activity ofF. religiosawas evaluated with thehelp of ulcer area and histopatholgical examination. Preliminary phyto-chemical screeningand acute toxicity studies ofF. religiosaalso carried out.Results:Results showed that theextract treatments prevented ulcer area and gastric secretion in a dose-dependent manner.Administration of 2000 mg/kg extract did not show any acute toxicity in albino mice. Preliminaryphytochemical analysis identified the presence of flavonoids in the ethanolic extract ofF. religiosa.Conclusions:The extract is non-toxic even at relatively high concentrations. The anti-ulceractivity is probably due to the presence of flavanoids. | Marslin Gregory B. Divya Revina Ann Mary M. M. Hipolith Viji V. K. Kalaichelvan V. Palanivel | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，7： | 1 |
| 8 | Defining human diabetic nephropathy on the molecular level: Integration of transcriptomic profiles with biological knowledge显示文摘 | Sebastian Martini Felix Eichinger Viji Nair Matthias Kretzler | 2008 | Reviews in Endocrine and Metabolic Disorders2008，，4： | 1 |
| 9 | Modulation of angiogenic factors by ursolic acid显示文摘 | Kiran MS Viji RI Sameer Kumar VB | 2008 | Biochem Biophys Res Commun2008，371，： | 1 |
| 10 | Suppression of gray leaf spot(blast)of perennial ryegrass turf by Pseudomonas aeruginosa from spent mushroom substrate显示文摘 | VIJI G UDDIN W ROMAINE C | 2003 | Biol Control2003，26，3： | 1 |
| 11 | Prevalence and outcome of acute kidney injury,as defined by the new Kidney Disease Improving Global Outcomes guideline,in very low birth weight infants显示文摘AIM To evaluate the prevalence, risk factors and outcome of acute kidney injury(AKI) in very low birth weight(VLBW) infants. METHODS In this retrospective study of VLBW infants, we analyzed the prevalence of AKI, as defined by changes in serum creatinine and urine output, associated risk factors and outcomes.RESULTS A total of 293 VLBW infants(mean gestational age 28.7 wk) were included, of whom 109 weighed less than 1000 g at birth. The overall prevalence of AKI was 11.6%(22% in infants with a birth weight under 1000 g and 5.4% those heavier). A total of 19(55%) affected infants died, with a mortality rate of 58% in infant less than 1000 g and 50% in those heavier. After adjusting for confounding variables, only necrotizing enterocolitis(NEC) remained associated with AKI, with odds ratio of 4.9(95%CI: 1.9-18.6). Blood pressure and glomerular filtration rate(GFR) were not different between affected infants and the others upon discharge from hospital. A normal GFR was documented in all affected infants at one year of age.CONCLUSION Using Kidney Disease Improving Global Outcomes definition of AKI, it occurred in over 10% of VLBW infants,more commonly in infants with lower birth weight. NEC was an independent associated risk factor. Renal function, as defined by GFR, was normal in all surviving affected infants 10 to 12 mo later. | Maisa Al Malla Nisha Viji Varghese Mustafa AlAbdullatif Hassib Narchi Mohammad Khassawneh | 2017 | World Journal of Nephrology2017，6，5： | 1 |
| 12 | A temperature and leaf wetness duration-based model for prediction of gray leaf spot of perennial ryegrass turf 显示文摘 | Uddin W Serlemitsos K Viji G | 2003 | Phytopathology2003，93，3： | 1 |
| 13 | DNA polymorphisms of isolates of Magnaporthe grisea from India that are pathogenic to finger millet and rice显示文摘 | Viji G Gnanamanickam S S Levy M | 2000 | Mycol Res2000，104，2： | 1 |
| 14 | A Phase 2 Trial of Flavopiridol (Alvocidib) and Cisplatin in Platin-Resistant Ovarian and Primary Peritoneal Carcinoma: MC0261显示文摘 | Keith C. Bible Prema P. Peethambaram Ann L. Oberg William Maples David L. Groteluschen Matthew Boente Jill K. Burton Leigh C. Gomez Dahl Jennifer D. Tibodeau Crescent R. Isham Jacie L. Maguire Viji Shridhar Andrea K. Kukla Kalli J. Voll Mathew J. Mauer Al | 2012 | Gynecologic Oncology2012，，1： | 1 |
| 15 | Modulation of angiogenic factors by ursolic acid 显示文摘 | KIRAN M S VIJI R I SAMEER KUMAR V B | 2008 | Biochem Biophys Res Commun2008，371，3： | 1 |
| 16 | Image segmentation in satellite image using optimal texture measures 显示文摘 | Viji G Nimitha N Kalarani A | 2012 | Inter- national Journal of Advanced Research in Computer Sci- ence and Electronics Engineering2012，1，6： | 1 |
| 17 | A temperature and leaf wetness suring-based model for prediction of gray leaf spot of perennial ryegrass turf显示文摘 | Uddin W Serlemitsos K Viji G 2003 | 2003 | Phytopathology2003，93，： | 1 |
| 18 | Identification of tubulins as substrates of serine protease HtrA1 by mixture-based oriented peptide library screening显示文摘 | JEREMY C HE XP VIJI S | 2009 | J Cell Biochem2009，107，2： | 1 |
| 19 | HtrA serine proteases as potential therapeutic targets in cancer显示文摘 | JEREMY C MARA C VIJI S | 2009 | Curr Cancer Drug Targets2009，9，4： | 1 |
| 20 | DNA polymorphisms of isolates of Magnaporthe gri sea fiom India that pathogenic to finger millet and rice显示文摘 | Viji G Gnanamanickam S S Levy M | 2000 | Mycological Research2000，104，： | 1 |
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