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| 1 | A complete compilation of matrix metalloproteinase expression in human malignant gliomas显示文摘Glioblastomas are characterized by an aggressive local growth pattern, a marked degree of invasiveness and poor prognosis. Tumor invasiveness is facilitated by the increased activity of proteolytic enzymes which are involved in destruction of the extracellular matrix of the surrounding healthy brain tissue. Elevated levels of matrix metalloproteinases(MMPs) were found in glioblastoma(GBM) cell-lines, as well as in GBM biopsies as compared with low-grade astrocytoma(LGA) and normal brain samples, indicating a role in malignant progression. A careful review of the available literature revealed that both the expression and role of several of the 23 human MMP proteins is controversely discussed and for some there are no data available at all. We therefore screened a panel of 15 LGA and 15 GBM biopsy samples for those MMPs for which there is either no, very limited or even contradictory dataavailable. Hence, this is the first complete compilation of the expression pattern of all 23 human MMPs in astrocytic tumors. This study will support a better understanding of the specific expression patterns and interaction of proteolytic enzymes in malignant human glioma and may provide additional starting points for targeted patient therapy. | Carsten Hagemann Jelena Anacker Ralf-Ingo Ernestus Giles H Vince | 2012 | World Journal of Clinical Oncology2012，3，5： | 18 |
| 2 | Heterogeneous regional expression patterns of matrix metalloproteinases in human malignant gliomas显示文摘 | Vince G H Wagner S Pietsch T | 1999 | Int J Dev Neurosci1999，17，56： | 1 |
| 3 | Prophylactic intravenous magnesium sulfate for treatment of aneurysmal subarachnoid hemorrhage:a randomized,placebo-controlled,clinical study显示文摘 | WESTERMAIER T STETTER C VINCE G H | 2010 | Crit Care Med2010，38，5： | 1 |
| 4 | Experimental demonstration of guiding and bending of electromangnetic waves in aphonic crystal显示文摘 | Shawnyu L Edmund C Vince H | 1998 | Science1998，282，5387： | 1 |
| 5 | Arach- noid cysts of the fourth ventricle-short il!ustrated review 显示文摘 | Westermaier T Vince G H Meinhardt M | 2010 | Acta Neurochir (Wien)2010，1521，： | 1 |
| 6 | Low birth weight at a Papua New Guinea highlands hospital显示文摘 | Vince JD Friesen H | 2001 | J Trp Pediatr2001，47，1： | 1 |
| 7 | Perinatal asphyxia at Port Moresby General Hospital: a study of incidence, risk factors and outcome 显示文摘 | Oswyn G Vince JD Friesen H | 2000 | PNG Med J2000，43，12： | 1 |
| 8 | Optical probe for high - temperature local void fraction determination 显示文摘 | Vince M A Breed H Krycuk G | 1982 | Applied Optics1982，21，5： | 1 |
| 9 | A random ized, double-blind, multiple-dose study of the pan-genotypie NS5A inhibitor samatasvir in patients infected with hepatitis C virus genotype 1,2,3 or 4 显示文摘 | BRADLEY VINCE JOHN M H ERIC J L | 2014 | J Hepatol2014，60，5： | 1 |
| 10 | Experimental demonstra- tion of guiding and bending of electromagnetic waves in a photonic crystal显示文摘 | Yu L S Edmund C Vince H | 1998 | Science1998，282，： | 1 |
| 11 | The crystal structure of a bis(2,6-pyridinedicarboxylato) chromate(Ⅲ) anion with an elaborate network of hydrogen bonding and π stacking显示文摘 | Vince C R P Oliver S C H Robert T S | 2007 | Journal of Chemical Crystallography2007，37，4： | 1 |
| 12 | Medulloblastoma displays distinct regional matrix metalloprotease expression显示文摘 | Vince G H Herbold C Klein R | 2001 | J Neuroon- col2001，53，： | 1 |
| 13 | Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro显示文摘 | Kerkau S Hanke A Bouterfa H Mueller JG Wagner S Vince GH Roosen K | 1999 | Int J Cancer1999，80，： | 1 |
| 14 | Advanced e- quation of state method for modeling TECr-water for glycol gas dehydration显示文摘 | CHORNG H T VINCE T WAYNE D S | 2005 | Fluid Phase Equilibrium2005，228，2： | 1 |
| 15 | Experimental demonstration of guiding and bending of electromagnetic waves in photonic crystal显示文摘 | Shawnyu L Edmund C Vince H | 1998 | Science1998，282，5387： | 1 |
| 16 | Biotransformation enzymes and thyroid axis disruption in juvenile rainbow trout (Oncorhynchus mykiss) exposed to hexabromocyclododecane diastereoisomers 显示文摘 | Vince PP Kerri P Thor H | 2008 | Environ Sci Technol2008，42，： | 1 |
| 17 | Spontaneous regression of experimental gliomas an immunohistochemical and MRI study of the C6 glioma spheroid implantation model 显示文摘 | Vince G H Bendszus M Schweitzer T | 2004 | Exp Neurol2004，190，2： | 1 |
| 18 | Prophylactic intravenous magnesium sulfate for treatment of aneurysmal subarachnoid hemorrhage:a randomized,placebo-controlled,clinical study显示文摘 | Westermaier T Stetter C Vince G H | 2010 | Crit Care Med2010，38，5： | 1 |
| 19 | Low birth weight at a Papua New Guinea highlands hospital显示文摘 | Vince JD Friesen H | 2001 | J Trp Pediatr2001，47，1： | 1 |
| 20 | Advanced equation of state method for modeling TEG-water for glycol gas dehydration显示文摘 | Chorng H T Vince T Wayne D S | 2005 | Fluid Phase Equilibrium2005，228，： | 1 |
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