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| 1 | New flexible endoscopic controlled stapler technique for the treatment of Zenker's diverticulum:A case series显示文摘AIM To report about the combination and advantages of a tapler-assisted diverticulotomy performed by flexible endoscopy.METHODS From November 2014 till December 2015 17 patients(8 female, 9 male, average age 69.8 years) with a symptomatic Zenker diverticulum(mean size 3.5 cm) were treated by inserting a new 5 mm fully rotatable surgical stapler(Micro Cutter30 Xchange, Cardica Inc.) next to an ultrathin flexible endoscope through an overtube. The Patients were under conscious sedation with the head reclined in left position, the stapler placed centrally and pushed forward to the bottom of the diverticulum. The septum was divided by the staple rows under flexible endoscopic control.RESULTS In eleven patients(64.7%) the stapler successfully divided the septum completely. Mean procedure time was 21 min, medium size of the septum was 2.8 cm(range 1.5 cm to 4 cm). In four patients the septum was shorter than 3 cm, in seven longer than 3 cm. To divide the septum, averagely 1.3 stapler cartridges were used. Two minor bleedings occurred. Major adverse events like perforation or secondary haemorrhage did not occur. After an average time of two days patients were discharged from the hospital. In 6 patients(35.3%) the stapler failed due to a thick septum or insufficient reclination of the head. Follow up endoscopy was performed after an average of two months in 9 patients; 4 patients(44.4%) were free of symptoms, 5 patients(55.6%) stated an improvement. A relapse of symptoms did not occur. CONCLUSION Flexible endoscopic Zenker diverticulotomy by using a surgical stapler is a new, safe and efficient treatment modality. A simultaneously tissue opening and occlusion prevents major complications. | Johanna Wilmsen Robert Baumbach Dietmar Stüker Vincens Weingart Frank Neser Stefan Karl Golder Christof Pfundstein Ellen Claudia Notzel Thomas Rosch Siegbert Faiss | 2017 | World Journal of Gastroenterology2017，23，17： | 2 |
| 2 | High-performance liquid chromatogaphy analysis of nectar and pollen of strawberry flowers显示文摘 | GRUNFEL E VINCEN C BAGNARA D | 1989 | Journal of Agricultural and Food Chemistry1989，37，： | 1 |
| 3 | A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome显示文摘 | Mark E Curran Igor Splawski Katherine W Timothy G.Michael Vincen Eric D Green Mark T Keating | 1995 | Cell1995，，： | 1 |
| 4 | Inhibition of endothelial cell migration bycerivastatin,an HMG-CoA reductase inhibitor:contribution to its anti-angiogenic effect显示文摘 | Vincen L Chen W Hong L | 2001 | FEBS Lett2001，495，： | 1 |
| 5 | Computational method to predict mitochondrially imported proteins and their targeting sequences显示文摘 | Claros M G Vincens P | 1996 | Eur J Biochem1996，241，3： | 1 |
| 6 | Computational method to prediet mitochon- drially imported proteins and their targeting sequences 显示文摘 | Claros M G Vincens P | 1996 | Eur J Biochem1996，241，3： | 1 |
| 7 | Efficacy and safety of recombinant human activated protein C for severe sepsis显示文摘 | Bernard GR Vincen JL Latterre PF | 2001 | N Engl J MED2001，344，10： | 1 |
| 8 | Pregnantwomen with advanced cervical cancer显示文摘 | Vincens C Dupaigne D de Tayrae R | 2008 | Gynecol Obstet Fertil2008，36，4： | 1 |
| 9 | Computational method to predict mitochondrially imported proteins and their targeting sequences显示文摘 | Claros M G Vincens P | 1996 | Eur J Biochem1996，241，3： | 1 |
| 10 | Computational method to predict mitochon- drially imported proteins and their targeting sequences 显示文摘 | Claros M G Vincens P | 1996 | Ear J Biochem1996，241，3： | 1 |
| 11 | Accuracy of magnetic resonance imaging in predicting residual disease in patients treated for stage IB2/II cervical carcinoma with chemoradiation therapy : correla- tion of radiologic findings with surgicopathologic results显示文摘 | Vincens E Balleyguier C Rey A | 2008 | Canc- er2008，113，8： | 1 |
| 12 | A stress-relieved resin-bonded fixed partial denture显示文摘 | Sanford P Vincen W Ralph P | 1989 | J Prosthet Dent1989，61，3： | 1 |
| 13 | Efficacy and safety of recombinant human activated protein C for severe sepsis显示文摘 | Bernard GR Vincen JL Latterre PF | 2001 | N Engl J Med2001，334，： | 1 |
| 14 | Microgel particles as model colloids: theory, properties and applications显示文摘 | Saunders B R Vincen B | 1999 | Advances in Colloid and Interface Science1999，80，1： | 1 |
| 15 | Characterization of chillingacclimation-related proteins in soybean and identification of one as amember of the heat shock protein HSP70 family显示文摘 | Cabane M Calvet P Vincens P | 1993 | Planta1993，190，3： | 1 |
| 16 | Computational method to predict mitochondrially imported proteins and their targeting sequences显示文摘 | Claros MG Vincens P | 1996 | Eur J Biochem1996，241，3： | 1 |
| 17 | Computational method to predict mitochondrially imported proteins and their targeting sequences 显示文摘 | Claros M G Vincens P | 1996 | Eur J Biochem1996，241，3： | 1 |
| 18 | Role of hepatitis C virus in lymphoproliferative disorders after liver transplantation显示文摘 | Christophe Hézode Christophe Duvoux Georgios Germanidis Fran?oise Roudot‐Thoraval Anne‐Laure Vincens Philippe Gaulard Daniel Cherqui Jean‐Michel Pawlotsky Daniel Dhumeaux | 2003 | Hepatology2003，，3： | 1 |
| 19 | Characterization of chilling- acclimation-related proteins in soybean and identification of one as a member of the heat shock protein (HSP 70) family显示文摘 | Cabane M Calvet P Vincens P | 1993 | Planta1993，190，3： | 1 |
| 20 | Assessing the greenness effort for European firms:A resource efficiency perspective显示文摘 | Vincen Y H | 2009 | Management Decision2009，47，7： | 1 |
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