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| 1 | Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains显示文摘Objective:To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach(M.azedarach) L.(Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains.Methods:Petrol,benzene,ethyl acetate,methanol,and aqueous extracts at five different concentrations(1,2,5,10 and 15 mg/mL) were evaluated.Disk diffusion method was followed to evaluate the antibacterial efficacy.Results:All extracts of the seeds demonstrated significant antibacterial activity against tested pathogens.Among all extracts,ethyl acetate extract revealed the highest inhibition comparatively.The present study also favored the traditional uses reported earlier.Conclusions:Results of this study strongly confirm that the seed extracts of M.azedarach could be effective antibiotics,both in controlling gram-positive and gram-negative human pathogenic infections. | Abdul Viqar Khan Qamar Uddin Ahmed M Ramzan Mir Indu Shukla Athar Ali Khan | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，6： | 11 |
| 2 | Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn,against pathogenic bacteria causing tropical diseases显示文摘Objective:To investigate antibacterial potential of Trifolium alexandrinum(T.alexandrinum) Linn,against seven gram positive and eleven gram negative hospital isolated human pathogenic bacterial strains responsible for many tropical diseases.Methods:Non-polar and polar extracts of the leaves of T.alexandrinum i.e.,hexane,dichloromethane(DCM),ethyl acetate(EtOAc), methanol(MeOH) and aqueous(AQ) extracts at five different concentrations(1,2,5,10 and 15 mg/ mL) were prepared to evaluate their antibacterial value.NCCL standards were strictly followed to perform antimicrobial disc susceptibility test using disc diffusion method.Results:Polar extracts demonstrated significant antibacterial activity against tested pathogens.EtOAc and MeOH extracts showed maximum antibacterial activity with higher inhibition zone and were found effective against seventeen of the tested pathogens.While AQ plant extract inhibited the growth of sixteen of the test strains.EtOAc and MeOH plant extracts inhibited the growth of all seven gram positive and ten of the gram negative bacterial strains.Conclusions:The present study strongly confirms the effectiveness of crude leaves extracts against tested human pathogenic bacterial strains causing several tropical diseases.Since Egyptian clover is used as a fodder plant,it could be helpful in controlling various infectious diseases associated with cattle as well. | Abdul Viqar Khan Qamar Uddin Ahmed Indu Shukla Athar Ali Khan | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，3： | 3 |
| 3 | Nepehinol--a new triterpene from Nepeta hindostana 显示文摘 | Viqar U A Shaheen B Faryal V M | 1985 | Planta Med1985，51，6： | 1 |
| 4 | Microbial decolorization of textile-dye-containing effluents:A Review显示文摘 | BANAT I M MARQUEZ M C VIQAR U A | 1996 | Bioresource Technology1996，，58： | 1 |
| 5 | 5 -Hydroxy- 3,6,7,2,5'- pentamethoxyflavone from Inula Grantioides 显示文摘 | Uddin Ahmad Viqar Ismail Nargis | 1991 | Phytochemistry1991，30，3： | 1 |
| 6 | Chemical constituents of Red Alga Botrycladia leptopoda 显示文摘 | SHAHEEN B VIQAR U A SHAISTA P | 1987 | Planta Medica1987，53，1： | 1 |
| 7 | Polymerase chain reaction-based genotype classification among human Blastocystis hominis populations isolated from different countries显示文摘 | Hisao Yoshikawa Zhiliang Wu Isao Kimata Motohiro Iseki Ibne Karim M. D. Ali Momammad B. Hossain Viqar Zaman Rashidul Haque Yuzo Takahashi | 2004 | Parasitology Research2004，，1： | 1 |
| 8 | Cytotoxic activity of marine macro‐algae on Artemia salina (Brine shrimp)显示文摘 | JehanAra ViqarSultana SyedEhteshamul‐Haque RashidaQasim Viqar UddinAhmad | 1999 | Phytother Res1999，，4： | 1 |
| 9 | Taraxacin, a new guaianolide from Taraxacum wallichii 显示文摘 | Viqar UA Shazia Y Zulfiqar A | 2000 | Journal of Natural Products2000，63，7： | 1 |
| 10 | Expression of gonadotropin receptor and growth responses to key reproductive hormones in normal and malignant human ovarian surface epithelial cell显示文摘 | Viqar S Marambaud P Shioi J | 2001 | Can Res2001，61，9： | 1 |
| 11 | Benzoic acid derivatives from Stocksia brahuica显示文摘 | Zulfiqar A Viqar U A Muhammacl Z | 1998 | Phytochemistry1998，48，7： | 1 |
| 12 | Use of Herbal Products and Potential Interactions in Patients With Cardiovascular Diseases显示文摘 | Ara Tachjian Viqar Maria Arshad Jahangir | 2010 | Journal of the American College of Cardiology2010，，6： | 1 |
| 13 | A new 14-membered cyclopeptide alkaloid from Zizyphus oxyphylla显示文摘 | Murad Ali Khan M. Arfan Gul Akhtar Lajber Khan Viqar Uddin Ahmad | 2007 | Natural Product Research2007，，3： | 1 |
| 14 | Expression of receptor and growth responsss to key reproductive hormones in normal and malignant human ovarian surface epithelilal cells显示文摘 | VIQAR SY GREGORY U SAMUEL C | 2001 | Cancer Res2001，61，： | 1 |
| 15 | Nepehinol - a new triterpene from Nepeta hindostana显示文摘 | Viqar U A Shaheen B Faryal V M | | 0，，06： | 1 |
| 16 | Expression of receptor and growth responses to key reproductive hormonesin normal and malignant human ovarian surface epithelilal cells显示文摘 | VIQAR S Y GREGORY U SAMUEL C | 2001 | Cancer Res2001，61，： | 1 |
| 17 | Steroidal saponins from Asparagus dumosus 显示文摘 | Ahmad Viqar Uddin Khaliq-uz-Zaman Syed Muhammad Shameel Simin | 1998 | Phytochemistry1998，50，： | 1 |
| 18 | 镰刀菌Fusarium solani菌株对卤虫Artemia salina的毒性(英文)显示文摘寻找能杀伤肿瘤细胞而对正常细胞无毒的抗癌药物极具挑战性。具有细胞毒性的植物或者真菌可能含有抗肿瘤的化合物。卤虫无节幼体的致死性可作为筛选抗肿瘤化合物的试验。本研究运用从不同农作物种子分离的 8株镰刀菌(Fusarium solani)培养滤液来测试卤虫的细胞毒性效果。结果表明,5株菌株(TS、S-29、B-17、C-10和W-5)对卤虫显示高毒性;3株菌株(SR、T-9和 L-25)显示低毒性,且毒性随着培养滤液的稀释而减弱。5 株菌株(TS、B-17、SR、T-9 和 L-25)按照 1∶10稀释能导致 30%以上的死亡率。NaOH中和后的滤液毒性略微降低,表明培养滤液的pH值可能影响毒性。这些菌株冻干的滤液相对于未冻干的滤液毒性较低。只在3株温和毒性的菌株中得到正己烷可溶萃取物;氯仿可溶萃取物的量极微而不能作进一步处理。各菌株的毒性效果各不相同。从镰刀菌(F. solani)分离的化合物可开发为毒性化合物。 | Shagufta Hameed Viqar Sultana Jehan Ara Syed Ehteshamul-Haque Mohammad Athar | 2009 | Zoological Research2009，30，4： | 1 |
| 19 | Expression of receptor and growth responses to key reproductive hormones in normal and malignant human ovarian surface epithelilal cells显示文摘 | Viqar SY Gregory U Samuel C | 2001 | Cancer Res2001，61，： | 1 |
| 20 | Phosphodiesterase-inhibiting glycosides from symplocos racemosa显示文摘 | VIQAR UA MUHAMMAD AA MUHAMMAD Z | 2004 | ttelvetica Chimica Acta2004，87，1： | 1 |
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