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| 1 | Hazard assessment of landslide disaster using information value method and analytical hierarchy process in highly tectonic Chamba region in bosom of Himalaya显示文摘The present study is focused on a comparative evaluation of landslide disaster using analytical hierarchy process and information value method for hazard assessment in highly tectonic Chamba region in bosom of Himalaya. During study, the information about the causative factors was generated and the landslide hazard zonation maps were delineated using Information Value Method(IV) and Analytical Hierarchy Process(AHP) using Arc GIS(ESRI). For this purpose, the study area was selected in a part of Ravi river catchment along one of the landslide prone Chamba to Bharmour road corridor of National Highway(NH^(-1)54 A) in Himachal Pradesh, India. A numeral landslide triggering geoenvironmental factors i.e. slope, aspect, relative relief, soil, curvature, land use and land cover(LULC), lithology, drainage density, and lineament density were selected for landslide hazard mapping based on landslide inventory. Landslide hazard zonation map was categorized namely 'very high hazard, high hazard, medium hazard, low hazard, and very low hazard'. The results from these two methods were validated using Area Under Curve(AUC) plots. It is found that hazard zonation map prepared using information value method and analytical hierarchy process methods possess the prediction rate of 78.87% and 75.42%, respectively. Hence, landslide hazardzonation map obtained using information value method is proposed to be more useful for the study area. These final hazard zonation maps can be used by various stakeholders like engineers and administrators for proper maintenance and smooth traffic flow between Chamba and Bharmour cities, which is the only route connecting these tourist places. | Kanwarpreet SINGH Virender KUMAR | 2018 | Journal of Mountain Science2018，15，4： | 12 |
| 2 | Development and characterization of an atorvastatin solid dispersion formulation using skimmed milk for improved oral bioavailability显示文摘Atorvastatin has low aqueous solubility resulting in low oral bioavailability(12%)and thus presents a challenge in formulating a suitable dosage form.To improve the aqueous solubility,a solid dispersion formulation of atorvasta tin was prepared by lyophilization utilising skimmed milk as a carrier.Six different formulations were prepared with varying ratios of drug and carrier and the corresponding physical mixtures were also prepared.The formation of a solid dispersion formulation was confirmed by differential scanning ca lorimetry and X-ray diffraction studies.The optimum drug-to-carrier ratio of 1:9 en hanced solubility nearly 33-fold as compared to pure drug.In vitro drug release studies exhibited a cumulative release of 83.69% as compared to 22.7% for the pure drug.Additionally,scanning electron microscopy studies suggested the conversion of crystalline atorvastatin to an amorphous form.In a Triton-induced hyperlipidemia model,a 3-fold increase in the lipid lowering potential was obtained with the reformulated drug as compared to pure drug.These results suggest that solid dispersion of atorvastatin using skimmed milk as carrier is a promising approach for oral delivery of atorvastatin. | Ankush Choudhary Avtar C.Rana Geeta Aggarwal Virender Kumar Foziyah Zakir | 2012 | Acta Pharmaceutica Sinica B2012，2，4： | 10 |
| 3 | 培养角膜缘上皮移植后穿透性角膜移植术的早期结果显示文摘目的:描述曾行培养角膜缘上皮移植的患者再行穿透性角膜移植(PKP)的早期结果。
方法:对因化学烧伤造成角膜缘干细胞缺乏而行培养的角膜缘上皮移植后又进行穿透性角膜移植术的患者有关人口统计学、原发病因、角膜缘移植类型、眼表稳定性、视力、移植片透明度和并发症方面的资料进行回顾和复习。对受体角膜片组织病理学特征进行研究,重点观察上皮状态。
结果:在患有角膜缘干细胞缺乏而进行培养的角膜缘上皮移植术的125例患者中,15例接受了穿透性角膜移植术(PKP)。角膜缘上皮移植术后(自体移植组n=11,同种异体移植组n=4)平均间隔时间为7个月(范围2—12个月)。同种异体移植组的4例患者均接受了免疫抑制疗法。15只眼中14只眼(93%)获得了含有稳定的角膜上皮的健全的角膜植片。15只眼中14只眼术前最佳矫正视力低于20/200。PKP后平均随访8.3±5.0个月,8只眼最佳矫正视力高于20/60,5只眼最佳矫正视力20/200至20/60。2只眼低于20/200。15只眼中3只眼发生异体角膜植片的排斥反应但被成功治疗。1只眼发生植片排斥的同时发生了青光眼。同种异体角膜缘上皮移植无一例显示排斥表现。
结论:培养的角膜缘上皮移植后,在形成稳定的眼表后行PKP的早期结果是良好的。为了避免排斥反应,培养的同种异体角膜缘上皮移植者行充分的免疫抑制治疗是必需的。角膜同种异体移植能够单独排斥同种异体角膜缘移植物。 | Virender S. Sangwan Himanshu P. Matalia Geeta K. Vemuganti Ghazala Ifihekar Anees Fatima Shashi Singh, Gullapalli N. Rao 董白霞(译) 马景学(校) | 2005 | 美国医学会眼科杂志(中文版)2005，17，4： | 5 |
| 4 | Durability of Radiofrequency Ablation in Barrett’s Esophagus With Dysplasia显示文摘 | Nicholas J. Shaheen Bergein F. Overholt Richard E. Sampliner Herbert C. Wolfsen Kenneth K. Wang David E. Fleischer Virender K. Sharma Glenn M. Eisen M. Brian Fennerty John G. Hunter Mary P. Bronner John R. Goldblum Ana E. Bennett Hiroshi Mashimo Richard I | 2011 | Gastroenterology2011，，2： | 3 |
| 5 | Obstructive Sleep Apnea, Obesity, and the Risk of Incident Atrial Fibrillation显示文摘 | Apoor S. Gami Dave O. Hodge Regina M. Herges Eric J. Olson Jiri Nykodym Tomas Kara Virend K. Somers | 2007 | Journal of the American College of Cardiology2007，，5： | 2 |
| 6 | Colloidal lead-free Cs_(2)AgBiBr_(6)double perovskite nanocrystals:Synthesis,uniform thin-film fabrication,and application in solution-processed solar cells显示文摘Recently developed lead-free double perovskite nanocrystals(NCs)have been proposed for the possible application in solutionprocessed optoelectronic devices.However,the optoelectronic applications of double perovskite NCs have been hampered due to the structural and chemical instability in the presence of polar molecules.Here,we report a facile strategy for the synthesis and purification of Cs_(2)AgBiBr_(6)double perovskite NCs that remained stable even after washing with polar solvent.This is realized with our efficient colloidal route to synthesize Cs_(2)AgBiBr_(6)NCs that involve stable and strongly coordinated precursor such as silvertrioctyl phosphine complex together with bismuth neodecanoate,which leads to a significantly improved chemical and colloidal stability.Using layer-by-layer solid-state ligand exchange technique,a compact and crack-free thin film of Cs_(2)AgBiBr_(6)NCs were fabricated.Finally,perovskite solar cells consisting of Cs_(2)AgBiBr_(6)as an absorber layer were fabricated and tested. | Razi Ahmad Gautam Virender Nutan Dinesh Singh Govind Gupta Udit Soni Sameer Sapra Ritu Srivastava | 2021 | Nano Research2021，14，4： | 2 |
| 7 | Silver nanoparticles: Green synthesis and their antimicrobial activities显示文摘 | Virender K. Sharma Ria A. Yngard Yekaterina Lin | 2008 | Advances in Colloid and Interface Science2008，，1： | 2 |
| 8 | 电针“足三里”穴对孕期及哺乳期尼古丁暴露新生鼠肺发育不良的影响显示文摘目的观察电针'足三里'穴对孕期及哺乳期尼古丁暴露新生鼠肺功能、肺指数和肺组织形态学的影响。方法将20只成年SD雌鼠采用随机数字表法分为生理盐水组(S组)、生理盐水加电针'足三里'组(S+ST36组)、尼古丁组(N组)、尼古丁加电针'足三里'组(N+ST36组),采用皮下注射尼古丁注射液[1 mg/(kg·d),100μL]造模,从妊娠第6天至新生鼠出生后21 d,用动物肺功能分析系统检测各组新生鼠肺功能,根据肺组织重量和体重计算各组新生鼠肺指数,采用HE染色法观察各组新生鼠肺组织形态学变化。结果与S组比较,N组呼气峰值(PEF)、肺动脉顺应性(Cdyn)显著降低(P<0.05),气道阻力(RL)显著增高(P<0.05),肺指数显著降低(P<0.05);新生鼠肺组织中肺泡数明显减少,肺泡体积增大,部分肺泡壁破裂相互融合。与N组比较,N+ST36组PEF、Cydn显著升高(P<0.05),RL显著降低(P<0.05),肺指数显著升高(P<0.05);新生鼠肺组织中肺泡数量增多、肺泡面积减小和肺泡壁破裂融合情况减少。结论电针孕期和哺乳期尼古丁暴露大鼠'足三里'穴可能通过改善新生鼠肺功能、肺指数及肺组织形态学变化发挥对新生鼠肺发育的保护效应。 | 刘翼天 嵇波 苏杭 葛云鹏 王丹 赵国桢 Reiko Sakurai Virender Kumar Rehan | 2018 | 中国医药导报2018，15，7： | 2 |
| 9 | 不同除草剂单独相继使用和混合使用防除小麦田虉草的效果比较(英文)显示文摘草是小麦田的主要杂草 ,尤其是水稻—小麦复种田块发生较为严重。用异丙隆防除 草已有 2 0多年的历史 ,防治效果十分显著。但近来有研究表明 草已具有对异丙隆的抗性。本试验研究了不同除草剂单独相继使用与混合使用对该杂草的防治效果。结果表明 ,播后 60 d,出苗前喷施氟乐灵和第一次灌水后喷施异丙隆的处理 ,除草效果最佳 ,而在成熟期 ,第一次灌水后喷施噻黄隆的处理具有与以上处理同样的防治效果。虽然使用异丙隆的处理产量最高 ,但一些除草剂单独相继使用也具有很好的杂草防治效果 ,小麦产量显著高于未用除草剂的对照。作者认为 ,在 草防治上存在有异丙隆抗性的地区 。 | Sardana Virender Brar LallSingh Mahajan Gulshan 张国平 | 2002 | 麦类作物学报2002，22，3： | 2 |
| 10 | Double-Balloon Enteroscopy and Capsule Endoscopy Have Comparable Diagnostic Yield in Small-Bowel Disease: A Meta-Analysis显示文摘 | Shabana F. Pasha Jonathan A. Leighton Ananya Das M. Edwyn Harrison G. Anton Decker David E. Fleischer Virender K. Sharma | 2008 | Clinical Gastroenterology and Hepatology2008，，6： | 2 |
| 11 | 电针对孕期饮食限制诱发宫内生长受限大鼠肺发育不良的影响显示文摘目的:探讨电针母鼠'足三里'穴对孕期饮食限制诱发宫内生长受限(IUGR)子代大鼠肺发育不良的保护效应。方法:将24只雌性SD大鼠随机分为对照组、对照电针组、模型组和模型电针组,每组6只。模型组和模型电针组大鼠从妊娠第10天至分娩期间,给予母鼠50%的饮食限制制备IUGR动物模型。对照电针组和模型电针组妊娠第10天至分娩期间,采用电针母鼠双侧'足三里'穴进行治疗,每日1次。在子代大鼠出生时测量其体质量,并在子代大鼠出生后第21天,测量其体质量和肺质量,采用小动物肺功能检测系统测定其肺功能;HE染色法观察肺组织形态;ELISA法检测肺组织中过氧化物酶体增殖物激活受体γ(PPARγ)含量。结果:与对照组比较,模型组子代大鼠出生时体质量及出生后第21天体质量、肺质量、肺动态顺应性(Cdyn)和PPARγ含量均降低(P<0.01),吸气峰值流速(PIF)值和吸气阻力(RI)值升高(P<0.01),肺泡数量减少,肺泡面积和肺泡间隔厚度增大,部分肺泡出现破裂、融合现象;与模型组比较,模型电针组子代大鼠出生时体质量及出生后第21天体质量、肺质量、Cdyn和PPARγ含量均升高(P<0.01,P<0.05),PIF值和RI值降低(P<0.05),肺泡数量增多,肺泡面积和肺泡间隔厚度减小,肺泡破裂、融合程度有所改善。结论:电针母鼠'足三里'穴可能通过调控肺组织中PPARγ含量,防护饮食限制诱发的IUGR大鼠肺功能和肺组织形态学改变。 | 牟秋杰 嵇波 赵国桢 刘翼天 戴健 路雅雯 Reiko Sakurai Virender Kumar Rehan 谢亚娜 张琴 石天宇 | 2021 | 中国针灸2021，41，4： | 2 |
| 12 | A national study of cardiopulmonary unplanned events after GI endoscopy <ce:link locator='fx1'/>显示文摘 | Virender K. Sharma Cuong C. Nguyen Michael D. Crowell David A. Lieberman Patricia de Garmo David E. Fleischer | 2007 | Gastrointestinal Endoscopy2007，，1： | 2 |
| 13 | Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia显示文摘 | Gavin C. Harewood Virender K. Sharma Pat de Garmo | 2003 | Gastrointestinal Endoscopy2003，，1： | 2 |
| 14 | Double-Balloon Enteroscopy and Capsule Endoscopy Have Comparable Diagnostic Yield in Small-Bowel Disease: A Meta-Analysis显示文摘 | Shabana F. Pasha Jonathan A. Leighton Ananya Das M. Edwyn Harrison G. Anton Decker David E. Fleischer Virender K. Sharma | 2008 | Clinical Gastroenterology and Hepatology2008，，6： | 2 |
| 15 | 电针对围产期尼古丁暴露新生鼠肺功能及肺形态的影响显示文摘目的:通过比较电针孕期及哺乳期尼古丁暴露母鼠'足三里'和'尺泽'穴对新生鼠肺功能和肺形态影响的差异,探讨能改善围产期尼古丁暴露引发新生鼠肺发育变化的特异效应穴位。方法:将24只雌性孕期SD大鼠随机分为正常组、模型组、足三里组、尺泽组,每组6只。自孕期第6天起,正常组皮下注射0.9%氯化钠溶液,余组均皮下注射尼古丁至产后第21天(生产当天不注射)制备孕期及哺乳期尼古丁暴露模型。采用每日2Hz/15Hz、1mA电针母鼠双侧'足三里'穴或'尺泽'穴治疗,与造模同时进行。实验结束后采用小动物肺功能测定仪测定子代鼠肺功能,HE染色法光镜下观测子代鼠肺泡化程度。结果:与正常组相比较,模型组吸气峰值流速(PIF)值、肺总阻力(RL)值和呼气相气道阻力(RE)值均显著升高(P<0.01),呼气峰值流速(PEF)值和肺动态顺应性(Cdyn)值均显著降低(P<0.01),模型组子代鼠肺泡数量减少,肺泡变形破裂融合,肺泡直径显著增加(P<0.01)。与模型组比较,足三里组PIF值、RL值和RE值均显著降低(P<0.01),PEF值和Cdyn值均显著升高(P<0.01,P<0.05),且肺泡数量明显增多,肺泡破裂现象改善,肺泡直径显著降低(P<0.01);尺泽组PIF值显著降低(P<0.01),RL值和RE值均明显降低(P<0.05),PEF值和Cdyn值有升高趋势,但差异无统计学意义(P>0.05),尺泽组肺泡数量明显增多,肺泡破裂现象改善,肺泡直径有减小趋势,但差异无统计学意义(P>0.05)。结论:电针'足三里'和电针'尺泽'均能通过改善孕期及哺乳期尼古丁暴露新生鼠肺功能及肺形态,防护子代鼠肺发育不良,且电针'足三里'穴效果优于电针'尺泽'穴。 | 葛云鹏 嵇波 赵国桢 刘翼天 苏杭 戴健 路雅雯 王丹 Reiko Sakurai Virender Kumar Rehan 严明娜 孙晓敏 白红新 郭孟玮 任晓暄 | 2019 | 针刺研究2019，44，2： | 2 |
| 16 | Silver nanoparticles: Green synthesis and their antimicrobial activities显示文摘 | Virender K. Sharma Ria A. Yngard Yekaterina Lin | 2008 | Advances in Colloid and Interface Science2008，，1： | 2 |
| 17 | Metabolic Syndrome and Risk of Incident Cardiovascular Events and Death显示文摘 | Apoor S. Gami Brandi J. Witt Daniel E. Howard Patricia J. Erwin Lisa A. Gami Virend K. Somers Victor M. Montori | 2007 | Journal of the American College of Cardiology2007，，4： | 2 |
| 18 | Retention of the capsule endoscope: a single-center experience of 1000 capsule endoscopy procedures显示文摘 | Feng Li Suryakanth R. Gurudu Giovanni De Petris Virender K. Sharma Arthur D. Shiff Russell I. Heigh David E. Fleischer Janice Post Paula Erickson Jonathan A. Leighton | 2008 | Gastrointestinal Endoscopy2008，，1： | 2 |
| 19 | Elimination of antibiotic resistance genes and control of horizontal transfer risk by UV-based treatment of drinking water: A mini review显示文摘Antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) have been recognized as one of the biggest public health issues of the 21 st century. Both ARB and ARGs have been determined in water after treatment with conventional disinfectants. Ultraviolet (UV) technology has been seen growth in application to disinfect the water. However, UV method alone is not adequate to degrade ARGs in water. Researchers are investigating the combination of UV with other oxidants (chlorine, hydrogen peroxide (H2O2), peroxymonosulfate (PMS), and photocatalysts) to harness the high reactivity of produced reactive species (C1-, C1O -, Cl2-,-OH, and SO4-_) in such processes with constituents of cell (e.g., deoxyribonucleic acid (DNA) and its components) in order to increase the degradation efficiency of ARGs. This paper briefly reviews the current status of different UV-based treatments (UV/chlorination, UV/H2O2, UV/PMS, and UV-photocatalysis) to degrade ARGs and to control horizontal gene transfer (HGT) in water. The review also provides discussion on the mechanism of degradation of ARGs and application of q-PCR and gel electrophoresis to obtain insights of the fate of ARGs during UV-based treatment processes. | Virender K.Sharma Xin Yu Thomas J.McDonald Chetan Jinadatha Dionysios D.Dionysiou Mingbao Feng | 2019 | Frontiers of Environmental Science & Engineering2019，13，3： | 2 |
| 20 | Capsule Endoscopy Versus Push Enteroscopy for Evaluation of Obscure Gastrointestinal Bleeding with 1-Year Outcomes显示文摘 | Jonathan A. Leighton MD Virender K. Sharma MD Joseph G. Hentz MS Danette Musil RN Marie J. Malikowski RN Tony L. McWane David E. Fleischer MD | 2006 | Digestive Diseases and Sciences2006，，5： | 2 |
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