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| 1 | Endoscopic ultrasound guided radiofrequency ablation,for pancreatic cystic neoplasms and neuroendocrine tumors显示文摘AIM: To outline the feasibility, safety, adverse events and early results of endoscopic ultrasound(EUS)-radiofrequency ablation(RFA) in pancreatic neoplasms using a novel probe. METHODS: This is a multi-center, pilot safety feasibility study. The intervention described was radiofrequency ablation(RF) which was applied with an innovative monopolar RF probe(1.2 mm Habib EUS-RFA catheter) placed through a 19 or 22 gauge fine needle aspiration(FNA) needle once FNA was performed in patients with a tumor in the head of the pancreas. The HabibTM EUSRFA is a 1 Fr wire(0.33 mm, 0.013') with a working length of 190 cm, which can be inserted through the biopsy channel of an echoendoscope. RF power is applied to the electrode at the end of the wire to coagulate tissue in the liver and pancreas.RESULTS: Eight patients [median age of 65(range 27-82) years; 7 female and 1 male] were recruited in a prospective multicenter trial. Six had a pancreatic cysticneoplasm(four a mucinous cyst, one had intraductal papillary mucinous neoplasm and one a microcystic adenoma) and two had a neuroendocrine tumors(NET) in the head of pancreas. The mean size of the cystic neoplasm and NET were 36.5 mm(SD ± 17.9 mm) and 27.5 mm(SD ± 17.7 mm) respectively. The EUSRFA was successfully completed in all cases. Among the 6 patients with a cystic neoplasm, post procedure imaging in 3-6 mo showed complete resolution of the cysts in 2 cases, whilst in three more there was a 48.4% reduction [mean pre RF 38.8 mm(SD ± 21.7 mm) vs mean post RF 20 mm(SD ± 17.1 mm)] in size. In regards to the NET patients, there was a change in vascularity and central necrosis after EUS-RFA. No major complications were observed within 48 h of the procedure. Two patients had mild abdominal pain that resolved within 3 d. CONCLUSION: EUS-RFA of pancreatic neoplasms with a novel monopolar RF probe was well tolerated in all cases. Our preliminary data suggest that the procedure is straightforward and safe. The response ranged from complete resolution to a 50% reduction in size. | Madhava Pai Nagy Habib Hakan Senturk Sundeep Lakhtakia Nageshwar Reddy Vito R Cicinnati Iyad Kaba Susanne Beckebaum Panagiotis Drymousis Michel Kahaleh William Brugge | 2015 | World Journal of Gastrointestinal Surgery2015，7，4： | 23 |
| 2 | Paclitaxel-eluting balloon dilation of biliary anastomotic stricture after liver transplantation显示文摘AIM:To investigate the safety and effectiveness of endoscopic therapy with a paclitaxel-eluting balloon(PEB) for biliary anastomotic stricture(AS) after liver transplantation(LT).METHODS:This prospective pilot study enrolled 13 consecutive eligible patients treated for symptomatic AS after LT at the University Hospital of Münster between January 2011 and March 2014.The patients were treated by endoscopic therapy with a PEB and followed up every 8 wk by endoscopic retrograde cholangiopancreatography(ERCP).In cases of re-stenosis,further balloon dilation with a PEB was performed.Follow-up was continued until 24 mo after the last intervention.RESULTS:Initial technical feasibility,defined as successful balloon dilation with a PEB during the initial ERCP procedure,was achieved in 100% of cases.Long-term clinical success(LTCS),defined as no need for further endoscopic intervention for at least 24 mo,was achieved in 12 of the 13 patients(92.3%).The mean number of endoscopic interventions required to achieve LTCS was only 1.7 ± 1.1.Treatment failure,defined as the need for definitive alternative treatment,occurred in only one patient,who developed recurrent stenosis with increasing bile duct dilatation that required stent placement.CONCLUSION:Endoscopic therapy with a PEB is very effective for the treatment of AS after LT,and seems to significantly shorten the overall duration of endoscopic treatment by reducing the number of interventions needed to achieve LTCS. | Anna Hüsing Holger Reinecke Vito R Cicinnati Susanne Beckebaum Christian Wilms Hartmut H Schmidt Iyad Kabar | 2015 | World Journal of Gastroenterology2015，21，3： | 4 |
| 3 | The surface energy of metals显示文摘 | L. Vitos A.V. Ruban H.L. Skriver J. Kollár | 1998 | Surface Science1998，，1： | 2 |
| 4 | The fabrication of polypyrrole nanostructure显示文摘 | de Vito S Martin C R | 1998 | Chem Mater1998，，10： | 1 |
| 5 | Cystatin C as a marker of early changes of renal function in Fabry nephropathy显示文摘 | Feriozzi S Germain D P Di Vito R | 2007 | J Nephrol2007，20，4： | 1 |
| 6 | Combined automatic lane-keeping and driver’s steering through a 2-DOF control strategy显示文摘 | VITO C MARIO M DIEGO R | 2009 | IEEE Transactions on Control Systems Technology2009，17，1： | 1 |
| 7 | Modeling and reasoning techniques in geological interpretation显示文摘 | VITO R CLAUDIO C | 1999 | IEEE Transactions on Systems Man and Cybemetics - Part A: Systems and Humans1999，29，5： | 1 |
| 8 | Arterial wall adaptation under elevated longitudinal stretch in organ culture显示文摘 | Han H C Ku D N Vito R P | 2003 | Ann Biomed Eng2003，31，4： | 1 |
| 9 | Cystatin C as a mark- er of early changes of renal function in Fabry nephropathy显示文摘 | Feriozzi S Germain DP Di Vito R | 2007 | J Nephrol2007，20，4： | 1 |
| 10 | The distribution of strain in the human cornea显示文摘 | Vito R P Johnson L W | 1997 | Biomechanics1997，30，5： | 1 |
| 11 | Virgin olive oil compounds from lipoxygenase pathway and characterization of some Italian cultivars显示文摘 | Angerosa F Basti C Vito R | 1999 | J Agric Food Chem1999，47，： | 1 |
| 12 | Expression of acrB, acrF, acrD, marA, and soxS in Salmonella enterica serovar Typhimuri- urn: role in multiple antibiotic resistance 显示文摘 | Deborah J E Laura J V P Vito R | 2004 | Antimicrob Agents Chemother2004，48，4： | 1 |
| 13 | Pathogenicity of Meloidogyne exigua on coffee (Co f f ea arabica) in pots显示文摘 | DI VITO M CROZZOLI R VOVLAS N | 2000 | Nematropica2000，30，1： | 1 |
| 14 | The seventh ring:exploring TRAF7 functions显示文摘 | Zotti T Vito P Stilo R | 2012 | J Cellular Physiol2012，227，： | 1 |
| 15 | Sepsis presenting as acute respiratory in sufficiency 显示文摘 | Dennis R Weisel R | 1974 | Surg Gynecol Obstet1974，138，： | 1 |
| 16 | Emergy-based simulation to assess Brazil′s long-term carrying capacity:Environment,electricity and population显示文摘 | DAVID R T VITO C | 2006 | Population and Environment2006，27，3： | 1 |
| 17 | Effect of low shear stress on permeability and occludin expression in porcine artery endothelial cells显示文摘 | CONKLIN B S VITO R CHEN C | 2007 | World J Surg2007，31，4： | 1 |
| 18 | Effects of central sympathetic inhibition on heart rate variability during steady-state exercise in healthy humans显示文摘 | Vito G D Galloway S D R Nimmo M A | 2002 | Clin Physiol & Func Im2002，22，： | 1 |
| 19 | Elderly subjects show severe impairment of dehydroepiandrosterone sulphate and reduced sensitivity of cortisol and aldosterone response to the stimulatory effect of ACTH (1-24) 显示文摘 | Giordano R Di Vito L Lanfranco F | 2001 | Clin Endocrinol (Oxf)2001，55，2： | 1 |
| 20 | Elderly subjects show severe impairment of dehydreepiandmsterene sulphate and reduced sensitivity of cortisol and aldosterone resDonse to the stimulatory efect of ACrrH(1-24)显示文摘 | Giordano R Di Vito L Lanfranco F Broqlio F Benso A Gianotti L Grottoli S Ghiqo E Arvat E | 2001 | Clin Endocrinol(Oxf)2001，55，2： | 1 |
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