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| 1 | Overview of coronary artery variants, aberrations and anomalies显示文摘Coronary artery anomalies and variants are relatively uncommon congenital disorders of the coronary artery anatomy and constitute the second most common cause of sudden cardiac death in young competitive athletes. The rapid advancement of imaging techniques, including computed tomography, magnetic resonance imaging, intravascular ultrasound and optical coherence tomography, have provided us with a wealth of new information on the subject. Anomalous origin of a coronary artery from the contralateral sinus is the anomaly most frequently associated with sudden cardiac death, in particular if the anomalous coronary artery has a course between the aorta and the pulmonary artery. However, other coronary anomalies, like anomalous origin of the left coronary artery from the pulmonary artery, atresia of the left main stem and coronary fistulae, have also been implicated in cases of sudden cardiac death. Patients are usually asymptomatic, and in most of the cases, coronary anomalies are discovered incidentally during coronary angiography or on autopsy following sudden cardiac death. However, in some cases, symptoms like angina, syncope, heart failure and myocardial infarction may occur. The aims of this article are to present a brief overview of the diverse coronary variants and anomalies, focusing especially on anatomical features, clinical manifestations, risk of sudden cardiac death and pathophysiologic mechanism of symptoms, as well as to provide valuable information regarding diagnostic workup, follow-up, therapeutic choices and timing of surgical treatment. | Stylianos Kastellanos Konstantinos Aznaouridis Charalambos Vlachopoulos Eleftherios Tsiamis Evangelos Oikonomou Dimitris Tousoulis | 2018 | World Journal of Cardiology2018，10，10： | 12 |
| 2 | Assessment of strain bursting in deep tunnelling by using the finite-discrete element method显示文摘Rockbursting in deep tunnelling is a complex phenomenon posing significant challenges both at the design and construction stages of an underground excavation within hard rock masses and under high in situ stresses. While local experience, field monitoring, and informed data-rich analysis are some of the tools commonly used to manage the hazards and the associated risks, advanced numerical techniques based on discontinuum modelling have also shown potential in assisting in the assessment of rockbursting. In this study, the hybrid finite-discrete element method(FDEM) is employed to investigate the failure and fracturing processes, and the mechanisms of energy storage and rapid release resulting in bursting, as well as to assess its utility as part of the design process of underground excavations.Following the calibration of the numerical model to simulate a deep excavation in a hard, massive rock mass, discrete fracture network(DFN) geometries are integrated into the model in order to examine the impact of rock structure on rockbursting under high in situ stresses. The obtained analysis results not only highlight the importance of explicitly simulating pre-existing joints within the model, as they affect the mobilised failure mechanisms and the intensity of strain bursting phenomena, but also show how the employed joint network geometry, the field stress conditions, and their interaction influence the extent and depth of the excavation induced damage. Furthermore, a rigorous analysis of the mass and velocity of the ejected rock blocks and comparison of the obtained data with well-established semi-empirical approaches demonstrate the potential of the method to provide realistic estimates of the kinetic energy released during bursting for determining the energy support demand. | Ioannis Vazaios Mark S.Diederichs Nicholas Vlachopoulos | 2019 | Journal of Rock Mechanics and Geotechnical Engineering2019，11，1： | 8 |
| 3 | Management of erectile dysfunction in hypertension:Tips and tricks显示文摘Arterial hypertension is a major risk factor for cardiovascular disease and affects approximately one third of the adult population worldwide. The vascular origin of erectile dysfunction is now widely accepted in the vast majority of cases. Erectile dysfunction is frequently encountered in patients with arterial hypertension and greatly affects their quality of life of hypertensive patients and their sexual partners. Therefore, the management of erectile dysfunction in hypertensive patients is of paramount importance. Unfortunately, erectile dysfunction remains under-reported, under-recognized, and under-treated in hypertensive patients, mainly due to the lack of familiarity with this clinical entity by treating physicians. This review aims to discuss the more frequent problems in the management of hypertensive patients with erectile dysfunction and propose ways to overcome these problems in everyday clinical practice. | Margus Viigimaa Charalambos Vlachopoulos Antonios Lazaridis Michael Doumas | 2014 | World Journal of Cardiology2014，6，9： | 5 |
| 4 | 平均动脉压、脉压与全因死亡率的纵向变化:来自71629名未经治疗的正常高值血压参与者的数据显示文摘血压通常包括平稳成分[平均动脉压(mean arterial pressure,MAP)]和波动成分,都可独立预测死亡率。目前还没有针对中心脉压(central pulse pressure,cPP)、肱动脉脉压(brachial pulse pressure,bPP)、MAP的纵向变化与死亡率之间关系的调查。方法:对年龄16~95岁未接受高血压治疗的71 629例参与者进行2次常规检查. | Protogerou AD Vlachopoulos C Thomas F Zhang Y Pannier B Blacher J Safar ME 陈云 | 2018 | 中华高血压杂志2018，26，8： | 4 |
| 5 | Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness显示文摘 | Charalambos Vlachopoulos Konstantinos Aznaouridis Christodoulos Stefanadis | 2010 | Journal of the American College of Cardiology2010，，13： | 3 |
| 6 | Utilizing a novel fiber optic technology to capture the axial responses of fully grouted rock bolts显示文摘Rock bolts are one of the primary support systems utilized in underground excavations within the civil and mining engineering industries. Rock bolts support the weakened rock mass adjacent to the opening of an excavation by fastening to the more stable, undisturbed formations further from the excavation. The overall response of such a support element has been determined under varying loading conditions in the laboratory and in situ experiments in the past four decades; however, due to the limitations with conventional monitoring methods of capturing strain, there still exists a gap in knowledge associated with an understanding of the geomechanical responses of rock bolts at the microscale. In this paper, we try to address this current gap in scientific knowledge by utilizing a newly developed distributed optical strain sensing(DOS) technology that provides an exceptional spatial resolution of 0.65 mm to capture the strain along the rock bolt. This DOS technology utilizes Rayleigh optical frequency domain reflectometry(ROFDR) which provides unprecedented insight into various mechanisms associated with axially loaded rebar specimens of different embedment lengths, grouting materials, borehole annulus conditions, and borehole diameters. The embedment length of the specimens was found to be the factor that significantly affected the loading of the rebar. The critical embedment length for the fully grouted rock bolts(FGRBs) was systematically determined to be430 mm. The results herein highlight the effects of the variation of these individual parameters on the geomechanical responses FGRBs. | Nicholas Vlachopoulos Daniel Cruz Bradley Forbes | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，2： | 3 |
| 7 | 勃起功能障碍患者中心血流动力学对心血管事件的预测作用显示文摘本研究调查中心血流动力学是否能够超越传统危险因素预测勃起功能障碍(erectile dysfunction,ED)患者主要不良心血管事件(major adverse cardiovascular events,MACE)的发生。方法:分析398例(平均年龄56年)ED但无确诊的心血管病患者的MACE与主动脉压和增强指数(augmentation index,AIx)之间的关系。 | Vlachopoulos C Ioakeimidis N Rokkas K Angelis A Terentes-Printzios D Kratiras Z Georgakopoulos C Tousoulis D 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，12： | 3 |
| 8 | An in situ monitoring campaign of a hard rock pillar at great depth within a Canadian mine显示文摘A recent research campaign at a Canadian nickel-copper mine involved instrumenting a hard rock sill drift pillar with an array of multi-point rod extensometers,distributed optical fibre strain sensors,and borehole pressure cells(BHPCs).The instrumentation spanned across a 15.24 m lengthwise segment of the relatively massive granitic pillar situated at a depth of 2.44 km within the mine.Between May 2016 and March 2017,the pillar’s displacement and pressure response were measured and correlated with mining activities on the same level as the pillar,including:(1)mine-by of the pillar,(2)footwall drift development,and(3)ore body stoping operations.Regarding displacements of the pillar,the extensometers provided high temporal resolution(logged hourly)and the optical fibre strain sensors provide high spatial resolution(measured every 0.65 mm along the length of each sensor).The combination of sensing techniques allowed centimetre-scale rock mass bulking near the pillar sidewalls to be distinguished from microstrain-scale fracturing towards the core of the pillar.Additionally,the influence and extent of a mine-scale schistose shear zone transecting the pillar was identified.By converting measured rock mass displacement to velocity,a process was demonstrated which allowed mining activities inducing displacements to be categorised by time-duration and cumulative displacement.In over half of the analysed mining activities,displacements were determined to prolong for over an hour,predominately resulting in submillimetre cumulative displacements,but in some cases multi-centimetre cumulative displacements were observed.This time-dependent behaviour was more pronounced within the vicinity of the plumb shear zone.Displacement measurements were also used to assess selected support member load and elongation mobilisation per mining activity.It was found that a combined static load and elongation capacity of reinforcing members was essential to maintaining excavation stability,while permitting gradual shedding of stress through controlled pillar sidewall displacements. | Bradley Forbes Nicholas Vlachopoulos Mark S.Diederichs Andrew J.Hyett Allan Punkkinen | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，3： | 2 |
| 9 | 生物标记,勃起功能障碍和心血管风险预测:不断发展的新观点显示文摘许多循环和影像学标记与心血管风险密切相关。勃起功能障碍(ED)生物标记能进一步优化治疗方案。有证据表明对于没有动脉粥样硬化临床表现的ED患者,生物标记能提高风险预测能力。对ED人群的更好鉴别需要进一步的风险分层和随机试验来验证生物标记预测心血管疾病风险的能力,以达到生物标记的疾病预防作用。 | Charalambos Vlachopoulos Nikolaos Ioakeimidis Christodoulos Stefanadis | 2015 | Asian Journal of Andrology2015，17，1： | 2 |
| 10 | 心血管病危险因素加速普通人群血管老化进程显示文摘以动脉结构及功能特点评估的血管老化是心血管病风险的一个独立预测因素。该研究假设心血管病危险因素的数量决定血管老化的进展。研究在2年间2次对142例未确诊心血管病的患者(平均年龄51.9岁,男性94例)进行检查评估。根据基线危险因素数量(0~≥2)对研究对象进行分组。 | Terentes-Printzios D Vlachopoulos C Xaplanteris P Ioakeimidis N Aznaouridis K Baou K Kardara D Georgiopoulos G Georgakopoulos C Tousoulis D 赵狄 练桂丽 | 2017 | 中华高血压杂志2017，25，10： | 2 |
| 11 | Bubble dissolution in molten polymers and its role in rotational molding 显示文摘 | M Kontopoulou J Vlachopoulos | 1999 | Polymer Engineering and Science1999，39，7： | 1 |
| 12 | CiS-X2Bis (2,2-bipyridyl-4,4-dicarboxylate)-ruthenium(Ⅱ) charge-transfer sensitizes (X=Cl-,Br-,I-,CN-and SCN-) on nanocrystalline TiO2 electrodes显示文摘 | GRATZEL M LISKA P VLACHOPOULOS N | 1993 | J Am Chem Soc1993，115，： | 1 |
| 13 | 显示文摘 | Hagfeldt A Vlachopoulos N Gratzel M etal | 1994 | Electrochem Soc1994，141，： | 1 |
| 14 | The effects of dual-orifice airring design on blown film cooling显示文摘 | Sidiropoulos V Vlachopoulos J | 2000 | Polymer Engineering&Science2000，40，7： | 1 |
| 15 | Prediction of cardiovascular events and all-cause mortality with arterial stiffness显示文摘 | Vlachopoulos C Aznaouridis K Stefanadis C | 2010 | J Am Coll Cardiol2010，55，13： | 1 |
| 16 | Periodontal condition of the mandibular anterior dentition in patients with conventional and self-ligating brackets显示文摘 | Pandis N Vlachopoulos K Polych ronopoulou A | 2008 | Orthod Craniofac Res2008，11，4： | 1 |
| 17 | The aerodynamics of cooling of blown film bubbles显示文摘 | Sidiropoulos V Wood P E Vlachopoulos J | 1999 | Journal of reinforced plastics and composites1999，18，6： | 1 |
| 18 | Benefits from angiotensin-converting enzyme inhibitor ‘beyond blood pressure lowering’: beyond blood pressure or beyond the brachial artery?显示文摘 | Kozo Hirata Charalambos Vlachopoulos Audrey Adji Michael F O?Rourke | 2005 | Journal of Hypertension2005，，3： | 1 |
| 19 | Inflam marion and arterial hypertension: from pathophysiological links to risk prediction显示文摘 | PIETRI P VLACHOPOULOS C TOUSOUI3S D | 2015 | Curr Med Chem2015，22，23： | 1 |
| 20 | Prediction of cardiovascular events and all-cause mortality with arterial stiffness; a systematic review and meta-analysis显示文摘 | Vlachopoulos C Aznaouridis K Stefanadis C | 2010 | J Am Coil Cardiol2010，55，： | 1 |
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