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| 1 | 乳汁免疫和猪流行性腹泻病毒病疫苗:历史和现状(译文)显示文摘由于肠道病毒感染导致仔猪在发病率、死亡率和生产能力丧失方面的影响,每年给养猪者带来数百万美元的损失。2013—2014年间,猪流行性腹泻病毒(PEDV)病的暴发给美国养猪业带来了9亿~18亿美元的经济损失。被动乳汁免疫被认为是保护新生哺乳仔猪免受PED等肠道疾病危害的最有希望和有效的方法。通过乳汁免疫被动保护哺乳仔猪的效果依赖于病原特异性IgA浆细胞转运至乳腺的数量和乳汁中分泌型IgA的积累程度,这种免疫途径被定义为'肠-乳腺-sIgA轴'。由于胎盘的不可穿透性,新生仔猪处于无免疫球蛋白的状态,对很多的传染性病原体极易感。它们仅依靠来源于母源的初乳和乳汁抗体获得被动保护。先前开发的关于猪传染性胃肠炎病毒(TGEV)病的活疫苗和灭活疫苗,提供了对母源性免疫和仔猪被动保护机制的理解。在这篇文章中,综述了猪传染性胃肠炎病毒诱导乳汁免疫的研究进展,并指出对当前养猪业正努力控制的猪流行性腹泻病毒感染和相关疫苗的研究方向。同时研究和鉴别出影响乳汁免疫和'肠-乳腺-sIgA轴'的各种因素,有助于改善妊娠母猪预防猪流行性腹泻病毒感染以及改进其它肠道病原用疫苗方案,从而达到提升整个猪群的免疫力、猪群健康和企业生产力的目的。 | Langel Stephanie N Paim Francine Chimelo Lager Kelly M Vlasova Anastasia N Saif Linda J 吕茂杰 | 2017 | 养猪2017，，1： | 3 |
| 2 | The prospective role of abnormal methyl metabolism in cadmium toxicity 显示文摘 | POIRIER L A VLASOVA T I | 2002 | Environ Health Perspect2002，110，5： | 1 |
| 3 | Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins显示文摘 | Vlasova IA Bohjanen PR | 2008 | RNA Biol2008，5，4： | 1 |
| 4 | The significance of blue light and kinetin for restoration of the photosynthetic apparatus in aging narley leaves显示文摘 | Voskresenskaya N P Nechayeva E P Vlasova M P | 1968 | Fizid Rast1968，15，： | 1 |
| 5 | Peroxidase-induced degradation of single-walled carbon nanotubes:Hypochlorite is a major oxidant capable of in vivo degradation of carbon nanotubes显示文摘 | Vlasova Ⅱ Vakhrusheva TV Sokolov AV | | 0，，： | 1 |
| 6 | Copolymerization of butadiene with isoprene in the presence of vanadium catalytic systems显示文摘 | Kudashev R K Vlasova N M Monakov Y B | 1982 | Prom-st Sint Kauch1982，，8： | 1 |
| 7 | Modifi-cation of chloroplast ultrastructure in pea plants greening under blue and red light显示文摘 | VLASOVA M P DROZDOVA S VOSKRESENSKAYA N P | 1971 | Fiziol Rast(USSR)1971，18，： | 1 |
| 8 | Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggre gation and oxidative stress in plasma and microphage显示文摘 | Kapralov A Vlasova II Feng W | 2009 | J Biol Chem2009，284，30： | 1 |
| 9 | Grinding slag from ferro-nickel process: some properties of the disperse system 显示文摘 | Vlasova M V | 2002 | Powder Technology2002，124，1： | 1 |
| 10 | Analysis of protective action of ischemic preconditioning from fluorescence spectra of blood serum and probes added to it显示文摘 | VLASOVA M SALETSKII A M | 2007 | Journal of Applied Spectroscopy2007，74，3： | 1 |
| 11 | Synthesis of ZrO2 :Eu solid solutions using homogeneous precipita- tion methods 显示文摘 | Vlasova K Yu Baranchikov A E Vanetsev A S | 2011 | Doklady Chemistry2011，436，： | 1 |
| 12 | Cardlovas- cular eeets of ghrelin antagonist in eomcfious mrs显示文摘 | VLASOVA M A JARVINEN K HERZIG K H | 2009 | Regtd Pept2009，156，： | 1 |
| 13 | Lactobacilli and Bifidobacteria promote im- mune homeostasis by modulating innate immune re- sponses to human rotavirus in neonatal gnotobiotic pigs 显示文摘 | VLASOVA A N CHATTHA K S KANDASAMY S | 2013 | PLoS One2013，8，76： | 1 |
| 14 | Peroxidase activi- ty of hemoglobin-haptoglobin complexes : covalent aggrega- tion and oxidative stress in plasma and microphage 显示文摘 | Kapralov A Vlasova II Feng W | 2009 | J Biol Chem2009，284，30： | 1 |
| 15 | Model of the lunar gravitationalfield,derived from luna 10,12,14,15 and 22 track-ing data显示文摘 | Akim E L Vlasova Z P | 1977 | DAN SSSR1977，235，： | 1 |
| 16 | Conserved GU-rich elements mediate mRNA decay by binding to CUG- binding protein 1 显示文摘 | VLASOVA I A TAHOE N M FAN D | 2008 | Mol Cell2008，29，2： | 1 |
| 17 | Circulating con- tact-pathway-activating microparticles together with factors IXa and XIa induce spontaneous clotting in plasma of hematology and cardiologic patients 显示文摘 | Lipets E Vlasova O Urnova E | 2014 | PLoS 0ne2014，9，87： | 1 |
| 18 | In vitro DNA methylation by wheat nuclear cytosine DNA methytransfcrase: effect of phytohormones 显示文摘 | Vlasova T I Demidenko Z N Kirnos M D | 1995 | Gene1995，157，： | 1 |
| 19 | Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggreg ation and oxidative stress in plasma and microphage显示文摘 | Kapralov A Vlasova II Feng W | 2009 | J Biol Chem2009，284，30： | 1 |
| 20 | The prospective role of abnormal methyl metabolism in cadmium toxicity显示文摘 | Poirier LA Vlasova TI | | Environ Health Perspect0，110，5： | 1 |
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