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| 1 | Closure of a persistent sphincterotomy-related duodenal perforation by placement of a covered self-expandable metallic biliary stent显示文摘Retroperitoneal duodenal perforation as a result of endoscopic biliary sphincterotomy is a rare complication, but it is associated with a relatively high mortality risk, if left untreated. Recently, several endoscopic techniques have been described to close a variety of perforations. In this case report, we describe the closure of a persistent sphincterotomy-related duodenal perforation by using a covered self-expandable metallic biliary (CEMB) stent. A 61-year-old Greek woman underwent an endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy for suspected choledo-cholithiasis, and a retroperitoneal duodenal perforation (sphincterotomy-related) occurred. Despite initial conservative management, the patient underwent a laparotomy and drainage of the retroperitoneal space. After that, a high volume duodenal fistula developed. Six weeks after the initial ERCP, the patient underwent a repeat endoscopy and placement of a CEMB stent with an indwelling nasobiliary drain. The fistula healed completely and the stent was removed two weeks later. We suggest the transient use of CEMB stents for the closure of sphincterotomy-related duodenal perforations. They can be placed either during the initial ERCP or even later if there is radiographic or clinical evidence that the leakage persists. | Antonios Vezakis Georgios Fragulidis Constantinos Nastos Anneza Yallourou Andreas Polydorou Dionisios Voros | 2011 | World Journal of Gastroenterology2011，17，40： | 11 |
| 2 | Surgical approaches of resectable synchronous colorectal liver metastases:Timing considerations显示文摘AIM: To compare the safety and efficacy of simultaneous versus two stage resection of primary colorectal tumors and liver metastases. METHODS: From January 1996 to May 2004, 103 colorectal tumor patients presented with synchronous liver metastases. Twenty five underwent simultaneous colorectal and liver surgery and 78 underwent liver surgery 1-3 mo after primary colorectal tumor resection. Data were retrospectively analyzed to assess and compare the morbidity and mortality between the surgical strategies. The two groups were comparable regarding the age and sex distribution, the types of liver resection and stage of primary tumors, as well as the number and size of liver metastases. RESULTS: In two-stage procedures more transfusions were required (4 ± 1.5 vs 2 ± 1.8, pRBCs, P < 0.05). Chest infection was increased after the two-stage approach (26% vs 17%, P < 0.05). The two-stage procedure was also associated with longer hospitalization (20 ± 8 vs 12 ± 6 d, P < 0.05). Five year survival in both groups was similar (28% vs 31%). No hospital mortality occurred in our series. CONCLUSION: Synchronous colorectal liver metastases can be safely treated simultaneously with the primary tumor. Liver resection should be prioritized over colon resection. It is advisable that complex liver resections with marginal liver residual volume should be dealt with at a later stage. | Ioannis Vassiliou Nick Arkadopoulos Theodosios Theodosopoulos Georgios Fragulidis Athanasios Marinis Agathi Kondi-Paphiti Lazaros Samanides Andreas Polydorou Constantinos Gennatas Dionysios Voros Vassilios Smyrniotis | 2007 | World Journal of Gastroenterology2007，13，9： | 8 |
| 3 | Predictors of common bile duct lithiasis in laparoscopic era显示文摘AIM: To analyze retrospectively the records of 294 conse-cutive patients operated upon for gallbladder stones, to determine the predictive factors of synchronous common bile duct (CBD) stones and validate prospectively the generated model. METHODS: The prognostic estimation of a biochemical test and ultrasonography alone to differentiate between the absence and presence of choledocholithiasis was assessed using receiver operating characteristics curve analysis. Multivariate analysis was employed using discriminant analysis for establishment of a best model. Prospective validation of the model was made.RESULTS: Discriminant forward stepwise analysis disclosed that high values (≥ 2×normal) of SGOT, ALP, conjugated bilirubin and CBD diameter on ultrasound ≥ 10 mm were all prognostic factors of CBD lithiasis in univariate and multivariate analysis, P<0.01. History was not included in the model. Prospective validation of the model was performed by multivariate analysis using Visual General Stepwise Regression. Positive predictive value,when considering all these predictors, was 93.3%, while the negative predictive value was 88.8%. Sensitivity of the model was 96.5% and specificity 80%.CONCLUSION: The above model can be objectively applied to predict the presence of CBD stones. | George Sgourakis Georgia Dedemadi Athanasios Stamatelopoulos Emmanuel Leandros Dionysius Voros Konstantinos Karaliotas | 2005 | World Journal of Gastroenterology2005，11，21： | 3 |
| 4 | Managing injuries of hepatic duct confluence variants after major hepatobiliary surgery:An algorithmic approach显示文摘AIM:To investigate injuries of anatomy variants of hepatic duct confluence during hepatobiliary surgery and their impact on morbidity and mortality of these procedures. An algorithmic approach for the management of these injuries is proposed. METHODS:During a 6-year period 234 patients who had undergone major hepatobiliary surgery were retrospectively reviewed in order to study postoperative bile leakage. Diagnostic workup included endoscopic and magnetic retrograde cholangiopancreatography (E/MRCP), scintigraphy and fistulography. RESULTS:Thirty (12.8%) patients who developed postoperative bile leaks were identified. Endoscopic stenting and percutaneous drainage were successful in 23 patients with bile leaks from the liver cut surface. In the rest seven patients with injuries of hepatic duct confluence, biliary variations were recognized and a stepwise therapeutic approach was considered. Conservative management was successful only in 2 patients. Volume of the liver remnant and functional liver reserve as well as local sepsis were used as criteria for either resection of the corresponding liver segment or construction of a biliary-enteric anastomosis. Two deaths occurred in this group of patients with hepatic duct confluence variants (mortality rate 28.5%). CONCLUSION:Management of major biliary fistulaethat are disconnected from the mainstream of the biliary tree and related to injury of variants of the hepatic duct confluence is extremely challenging. These patients have a grave prognosis and an early surgical procedure has to be considered. | Georgios Fragulidis Athanasios Marinis Andreas Polydorou Christos Konstantinidis Georgios Anastasopoulos John Contis Dionysios Voros Vassilios Smyrniotis | 2008 | World Journal of Gastroenterology2008，14，19： | 3 |
| 5 | A jasmonate-responsive lipoxygenase of barley leavesis induced by plant activators but not by pathogens显示文摘 | Hause B Voros K Kogel KH 1999 | 1999 | J Plant Physiol1999，154，： | 2 |
| 6 | Ischemic Preconditioning Confers Antiapoptotic Protection During Major Hepatectomies Performed Under Combined Inflow and Outflow Exclusion of the Liver. A Randomized Clinical Trial显示文摘 | Nikolaos Arkadopoulos Georgia Kostopanagiotou Kassiani Theodoraki Charalambos Farantos Theodosios Theodosopoulos Vaia Stafyla John Vassiliou Dionyssios Voros Agathi Pafiti Vassilios Smyrniotis | 2009 | World Journal of Surgery2009，，9： | 2 |
| 7 | Selective Hepatic Vascular Exclusion versus Pringle Maneuver in Major Liver Resections: Prospective Study显示文摘 | Vassilios E. Smyrniotis M.D. Ph.D. Georgia G. Kostopanagiotou M.D. Ph.D. John C. Contis M.D. Ph.D. Charalampos I. Farantos M.D. Dionisios C. Voros M.D. Ph.D. Dimitrios C. Kannas M.D. Ph.D. John S. Koskinas M.D. Ph.D | 2003 | World Journal of Surgery2003，，7： | 2 |
| 8 | Interrelations between Azospirillum and Rhizobium nitrogen-fixers and arbusculax mycorrhizal fungi in the rhizosphere of alfalfa in sterile, AMF-free or normal soil conditions 显示文摘 | Bito B Koves-Pehy K Voros I | 2000 | Applied Soil Ecology2000，15，2： | 1 |
| 9 | Prioritizing Abandoned Coal Mine Reclamation Projects within the Contiguous United States Using Geographic显示文摘 | Yuri Gorokhovich Andrew Voros Matthew Reid | 2003 | Information System Extrapolation Environmental Management2003，32，4： | 1 |
| 10 | Retroperitoneal tumors:do the satellite tumors mean something显示文摘 | Voros D Theodoron D Ventouri K | 1998 | J Surg Oncol1998，68，1： | 1 |
| 11 | Quantification of left ventricular parameters obtained by automated software for 64-slice multidetector computed tomography and comparison with magnetic resonance imaging显示文摘 | Akram K Anderson HD Voros S | | 0，，06： | 1 |
| 12 | The dynamics of Price, Quality and Productivity Improvement Decisions显示文摘 | Voros J | 2006 | European Journal of Operational Research2006，，170： | 1 |
| 13 | The Explicit Derivation of the Portfolio Frontier in the Case of Degeneracy and Ceneral Singularity显示文摘 | Voros J | 1987 | FJOR1987，，36： | 1 |
| 14 | Phytoplankton biomass and chlorophyll-a in some shallow lakes in central Europe显示文摘 | Voros L Padisák J | 1991 | Hydrobiologia1991，215，： | 1 |
| 15 | Freshwater pieocyanobaeteria along atrophic gradient and light quality range 显示文摘 | VOROS L CALLIERI C BALOGH K V | 1998 | Hydrobiologia1998，，： | 1 |
| 16 | Phytoplankton and bacterioplankton production in a reed-covered water body显示文摘 | Voros L Katalin V B Eszter K | 2003 | Aquat Bot2003，77，： | 1 |
| 17 | A generic foresight process framework显示文摘 | Voros J | 2003 | Foresight2003，5，3： | 1 |
| 18 | Sexual dysfunction among patients treated with antidepressants-a Hungarian retrospective study显示文摘 | Osvath P Fekete S Voros V | 2003 | Eur Psychiatry2003，18，18： | 1 |
| 19 | Comprehensiveplaque assessment by coronary CT angiography 显示文摘 | Maurovich-Horvat P Ferencik M Voros S | 2014 | Nat RevCardiol2014，11，7： | 1 |
| 20 | Shortcut design of windfarms显示文摘 | Kiranoudis C T Voros N G Maroulis Z B | 2001 | Energy Policy2001，29，7： | 1 |
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