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| 1 | Intravenous im- mune globulin versus intravenous anti- D immune globulin for the treatment of acute immune thrombocytopenic purpura显示文摘 | SHAHGHOLI E VOSOUGH P SOTOUDEN K | 2008 | Indian J Pe- diatr2008，75，12： | 1 |
| 2 | Organoids: a novel modality in disease modeling显示文摘Limitations of monolayer culture conditions have motivated scientists to explore new models that can recapitulate the architecture and function of human organs more accurately.Recent advances in the improvement of protocols have resulted in establishing three-dimensional(3D)organ-like architectures called‘organoids’that can display the characteristics of their corresponding real organs,including morphological features,functional activities,and personalized responses to specific pathogens.We discuss different organoid-based 3D models herein,which are classified based on their original germinal layer.Studies of organoids simulating the complexity of real tissues could provide novel platforms and opportunities for generating practical knowledge along with preclinical studies,including drug screening,toxicology,and molecular pathophysiology of diseases.This paper also outlines the key challenges,advantages,and prospects of current organoid systems. | Zahra Heydari Farideh Moeinvaziri Tarun Agarwal Paria Pooyan Anastasia Shpichka Tapas KMaiti Peter Timashev Hossein Baharvand Massoud Vosough | 2021 | Bio-Design and Manufacturing2021，4，4： | 1 |
| 3 | Prenatal diagnosis of fetal abdominal umbilical vein varix in an intracytoplasmic sperm injection:A case report显示文摘 | Ahmadi F Vosough Taghi Dizaj A Irani SH | | 0，，02： | 1 |
| 4 | The antieanmeer aelivity of five species of Artemisia on Hep2 and HepG2 cell lines显示文摘 | Seyed Ahmad Emami Nasser Vahdali-Mashhadian Remisa Vosough el al | 2009 | Pharacologyanline2009，3，： | 1 |
| 5 | Intravenous im mune globulin versus intravenous anti-D immune globulin for the treatment of acute immune thrombocytopenic purpura显示文摘 | Shahgholi E Vosough P Sotoudeh K | 2008 | Indian J Pediatr2008，75，12： | 1 |
| 6 | Cel-l basedtherapeutics for liver disorders显示文摘 | Vosough M Moslem M Pournasr B | 2011 | Br Med Bull2011，100，： | 1 |
| 7 | Intravenous immune globulin versus intravenous anti-D immune globulin for the treatment of acute immune thromboeytopenie purpura显示文摘 | Shahgholi E Vosough P Sotoudeh K | 2008 | Indian J Pediatr2008，75，12： | 1 |
| 8 | Chemometricsenhanced HPLC-DAD performance for rapid quantification ofcarbamazepine and phenobarbital in human serum samples显示文摘 | Vosough M Ghafghazi S Sabetkasaei M | 2014 | Talanta2014，119，： | 1 |
| 9 | Intravenous im- mune globulin versus intravenous anti-D immune globulin for the treatment of acute immune thrombocytopenic purpura 显示文摘 | Shahgholi E Vosough P Sotoudeh K | 2008 | Indian J Pediatr2008，75，12： | 1 |
| 10 | Fast liquid chromatogra?phy-diode array detection assisted by chemometrics for quantification of seven ultraviolet filters in effluent wastewater显示文摘 | Vosough M Mojdehi N R | 2011 | Talanta2011，85，4： | 1 |
| 11 | Simultaneous spectrophotometric deterrnination of folic acid, thiamin, riboflavin, and pyridoxal using partial lease-squares regression method显示文摘 | GHASEMI J VOSOUGH M | 2002 | Spectroscopy Letter2002，35，2： | 1 |
| 12 | Biofabrication of size-controlled liver microtissues incorporated with ECM-derived microparticles to prolong hepatocyte function显示文摘Multicellular microtissues of primary human hepatocytes(PHHs)co-cultured with other supporting cell types are a promis-ing model for drug screening and toxicological studies.However,these liver microtissues(LMs)rapidly lose their functions during ex vivo culture.Here,in order to mimic the cellular and structural hepatic microenvironment,we co-cultured PHHs with human mesenchymal stromal cells(MSCs)and human umbilical vein endothelial cells(HUVECs)in the presence of cell-sized microparticles(MPs)derived from liver extracellular matrix(LEMPs).The microwell culture platform enabled biofabrication of size-controlled multicellular microtissues(PHH:HUVEC:MSC=3:2:1)with efficient LEMP incorporation(about 70%at a 2:1 ratio of cells:MP).The biofabricated liver microtissues(BLMs)were cultured ex vivo for 14 days and compared to the cell-only LM in terms of gene and protein expression,functional activity,cytochrome P450(CYP450)enzyme inducibility,and drug sensitivity.The results supported superior hepatic-related gene expression,functional activity,and polarity for PHH in BLM compared to LM.CYP450 enzyme inducibility and dose-responsive sensitivity to toxic drugs were significantly higher in the BLM group.In conclusion,microtissue engineering by incorporation of tissue-specific microparticles within a multicellular microtissue can offer some advantages for drug discovery studies and cell transplantation applications.In the near future,this approach could generate a scalable platform of several functional biofabricated microtissues representing different organs. | Zahra Heydari Ibrahim Zarkesh Mohammad-Hossein Ghanian Mahdokht HAghdaei Svetlana Kotova Ensieh Zahmatkesh Zahra Farzaneh Abbas Piryaei Iman Akbarzadeh Anastasia Shpichka Roberto Gramignoli Peter Timashev Hossein Baharvand Massoud Vosough | 2021 | Bio-Design and Manufacturing2021，4，4： | 0 |
| 13 | Engineering biomimetic intestinal topological features in 3D tissue models: retrospects and prospects显示文摘Conventional 2D intestinal models cannot precisely recapitulate biomimetic features in vitro and thus are unsuitable for various pharmacokinetic applications,development of disease models,and understanding the host-microbiome interactions.Thus,recently,efforts have been directed toward recreating in vitro models with intestine-associated unique 3D crypt-villus(for small intestine)or crypt-lumen(for large intestine)architectures.This review comprehensively delineates the current advancements in this research area in terms of the different microfabrication technologies(photolithography,laser ablation,and 3D bioprinting)employed and the physiological relevance of the obtained models in mimicking the features of native intestinal tissue.A major thrust of the manuscript is also on highlighting the dynamic interplay between intestinal cells(both the stem cells and differentiated ones)and different biophysical,biochemical,and mechanobiological cues along with interaction with other cell types and intestinal microbiome,providing goals for the future developments in this sphere.The article also manifests an outlook toward the application of induced pluripotent stem cells in the context of intestinal tissue models.On a concluding note,challenges and prospects for clinical translation of 3D patterned intestinal tissue models have been discussed. | Tarun Agarwal Valentina Onesto Lallepak Lamboni Aafreen Ansari Tapas K.Maiti Pooyan Makvandi Massoud Vosough Guang Yang | 2021 | Bio-Design and Manufacturing2021，4，3： | 0 |
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