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| 1 | Effect of Graphene Nanoribbons (TexasPEG) on locomotor function recovery in a rat model of lumbar spinal cord transection显示文摘A sharply transected spinal cord has been shown to be fused under the accelerating influence of membrane fusogens such as polyethylene glycol(PEG)(GEMINI protocol). Previous work provided evidence that this is in fact possible. Other fusogens might improve current results. In this study, we aimed to assess the effects of PEGylated graphene nanoribons(PEG-GNR, and called 'Texas PEG' when prepared as 1 wt% dispersion in PEG600) versus placebo(saline) on locomotor function recovery and cellular level in a rat model of spinal cord transection at lumbar segment 1(L_1) level. In vivo and in vitro experiments(n = 10 per experiment) were designed. In the in vivo experiment, all rats were submitted to full spinal cord transection at L_1 level. Five weeks later, behavioral assessment was performed using the Basso Beattie Bresnahan(BBB) locomotor rating scale. Immunohistochemical staining with neuron marker neurofilament 200(NF200) antibody and astrocytic scar marker glial fibrillary acidic protein(GFAP) was also performed in the injured spinal cord. In the in vitro experiment, the effects of Texas PEG application for 72 hours on the neurite outgrowth of SH-SY5 Y cells were observed under the inverted microscope. Results of both in vivo and in vitro experiments suggest that Texas PEG reduces the formation of glial scars, promotes the regeneration of neurites, and thereby contributes to the recovery of locomotor function of a rat model of spinal cord transfection. | C-Yoon Kim William K. A. Sikkema Jin Kim Jeong Ah Kim James Walter Raymond Dieter Hyung-Min Chung Andrea Mana James M. Tour Sergio Canavero | 2018 | Neural Regeneration Research2018，13，8： | 2 |
| 2 | Postoperative central nervous system infe-ction: incidence and associated taetors in2111 neurosurgical procedures显示文摘 | Shearwood M Walter AH | 2007 | Clin Infect Dis2007，45，： | 1 |
| 3 | R-spondin1, A Novel Intestinotrophic Mitogen, Ameliorates Experimental Colitis in Mice显示文摘 | Jingsong Zhao Josephine de Vera Seiko Narushima Eric X. Beck Servando Palencia Pauline Shinkawa Kyung–Ah Kim Yi Liu Michael D. Levy Daniel J. Berg Arie Abo Walter D. Funk | 2007 | Gastroenterology2007，，4： | 1 |
| 4 | Postoperative central nervous system infection: incidence and associated factors in neurosurgical procedures显示文摘 | SHEARWOOD M WALTER AH | 2007 | Clin Infect Dis2007，45，： | 1 |
| 5 | Surgical approaches to the management of epithelial cysts显示文摘 | Julia AH Walter JS Amr A | 2002 | Trans Am Ophthalmol Soc2002，100，： | 1 |
| 6 | Iron metabolism, iron deficien- cy, thrombocytosis, and the cardiorenal anemia syndrome 显示文摘 | Besarab AH Walter H Silverberg D | 2009 | Oncolo- gist2009，14，1： | 1 |
| 7 | The integration of computed tomography and magnetic resonance imaging in treatment planning for gynecologic cancer显示文摘 | Russell AH Anderson M Walter J | 1992 | Clin Obstet Gynecol1992，35，1： | 1 |
| 8 | Postoperative central nerous system infection: incidence and associated factors in 211 neurosurgieal procedures显示文摘 | Shearwood M Walter AH | 2007 | Clin Infect Dis2007，45，： | 1 |
| 9 | The incidence of birthmarks in the neonate显示文摘 | Walter RG | 1976 | Pediatrics1976，58，： | 1 |
| 10 | Malignant glial tumor arising arising from the site of a previous hamartoma/ganglioglioma:coincidence or malignant transformation显示文摘 | Mittler MA Walters BC Fried AH | | 0，，： | 1 |
| 11 | High-frequency, low- magnitude vibrations suppress the number of blood vessels per muscle fiber in mouse soleus muscle显示文摘 | Walter LM Laura AH Caroline E | 2005 | J Appl Physiol2005，98，2： | 1 |
| 12 | Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain harrier for the treatment of patients with malignant brain turnors显示文摘 | Nancy DD Michael EM Walter AH | 2000 | Cancer2000，88，3： | 1 |
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