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| 1 | Model for end-stage liver disease (MELD) and allocation of donor livers显示文摘 | Russell Wiesner Erick Edwards Richard Freeman Ann Harper Ray Kim Patrick Kamath Walter Kremers John Lake Todd Howard Robert M. Merion Robert A. Wolfe Ruud Krom | 2003 | Gastroenterology2003，，1： | 2 |
| 2 | An economic perspective on transnational terrorism显示文摘 | Todd Sandler Walter Enders | 2003 | European Journal of Political Economy2003，，： | 2 |
| 3 | Increasing Evapotransp iration from the Conterminous United States显示文摘 | Walter M Todd Daniel S wilks | 2004 | Journal of Hydrology2004，，5： | 1 |
| 4 | Methane combustion over La2O3-based catalysts and γ-Al2O3显示文摘 | Todd J Toops Arden B Walters M Albert Vannice | 2002 | Applied Catalysis A:General2002，233，： | 1 |
| 5 | Model for end-stage liver disease (MELD) and allocation of donor livers显示文摘 | Russell Wiesner Erick Edwards Richard Freeman Ann Harper Ray Kim Patrick Kamath Walter Kremers John Lake Todd Howard Robert M. Merion Robert A. Wolfe Ruud Krom | 2003 | Gastroenterology2003，，1： | 1 |
| 6 | Outcomes of pancreatic debridement in acute pancreatitis: analysis of the nationwide inpatient sample from 1998 to 2010显示文摘 | Blair A. Wormer Ryan Z. Swan Kristopher B. Williams Joel F. Bradley Amanda L. Walters Vedra A. Augenstein John B. Martinie B. Todd Heniford | 2013 | The American Journal of Surgery2013，，： | 1 |
| 7 | Assessing the Impact of Terrorist- Thwarting Policies: An Intervention Time Series Approach显示文摘 | Enders Walter Todd Sandler Jon Cauley | 1990 | Defense Economics1990，，2： | 1 |
| 8 | The impact of portal vein resection on outcomes for hilar cholangiocarcinoma显示文摘 | Mechteld C. de Jong Hugo Marques Bryan M. Clary Todd W. Bauer J. Wallis Marsh Dario Ribero Pietro Majno Ioannis Hatzaras Dustin M. Walters Andrew S. Barbas Raquel Mega Richard D. Schulick Michael A. Choti David A. Geller Eduardo Barroso Gilles Mentha Lore | 2012 | Cancer2012，，19： | 1 |
| 9 | Etiologic Agents and Diseases Found Associated with Clinical Aspergillosis in Falcons显示文摘 | Walter Tarello Todd R. Callaway | 2011 | International Journal of Microbiology2011，，： | 1 |
| 10 | Process - Based Snowmelt Modeling:Does It RequireMore Input Data Than Temperature - Index Modeling显示文摘 | WALTER Todd BROOKS E S MCCOOL Donald K etal | 2005 | Journal of Hydrology2005，300，： | 1 |
| 11 | Greenhouse and field resistance in cucumber to root-knot nematodes显示文摘 | S. Alan Walters Todd C. Wehner Kenneth R. Barker | 1999 | Nematology1999，，3： | 1 |
| 12 | A soil- water-balance approach to quantify groundwater recharge from irrigated cropland in the North China Plain显示文摘 | Kendy E Gerard-Marchant P Todd Walter M | 2003 | Hydrological Processes2003，17，10： | 1 |
| 13 | The impact of portal vein resection on outcomes for hilar cholangiocarcinoma显示文摘 | Mechteld C. de Jong Hugo Marques Bryan M. Clary Todd W. Bauer J. Wallis Marsh Dario Ribero Pietro Majno Ioannis Hatzaras Dustin M. Walters Andrew S. Barbas Raquel Mega Richard D. Schulick Michael A. Choti David A. Geller Eduardo Barroso Gilles Mentha Lore | 2012 | Cancer2012，，19： | 1 |
| 14 | Rain- fall induced chemical transport from soil to runoff the ory and experiments 显示文摘 | Gao Bin Todd Walter W Steenhuis T S | 2004 | Journal of Hydrology2004，295，29： | 1 |
| 15 | Fear of Negative Evaluation Affects Helping Behavior: The Bystander Effect Revisited 显示文摘 | Karakashian L M Walter M I Christopher A N Todd L | 2006 | North American Journal of Psychology2006，8，1： | 1 |
| 16 | The use of anti- depressants for headache prophylaxis 显示文摘 | Todd A Smitherman A Walters B | 2011 | CNS Neuro- science Therapeutics2011，17，5： | 1 |
| 17 | PAC突破传统PLC显示文摘现在登陆任何工业控制论坛,我们可能都会看到有关基于PC控制和可编程逻辑控制器(PLC)控制的优缺点,也会看到某些有关PAC的讨论。然而,PAC究竟是什么?它具备哪些重要特点? | Todd Walter | 2005 | 现代制造2005，，11： | 0 |
| 18 | A nano-enhanced vaccine for metastatic melanoma immunotherapy显示文摘Aim:Despite the huge advancements in cancer therapies and treatments over the past decade,most patients with metastasized melanoma still die from the disease.This poor prognosis largely results from resistance to conventional chemotherapies and other cytotoxic drugs.We have previously identified 6 antigenic peptides derived from melanomas that have proven efficacious for activating CD4+T cells in clinical trials for melanoma.Our aim was to improve pharmacodynamics,pharmacokinetic and toxicological parameters by individually encapsulating each of the 6 melanoma helper peptides within their own immunogenic nanoliposomes.Methods:We modified these liposomes as necessary to account for differences in the peptides’chemical properties,resulting in 3 distinct formulations.To further enhance immunogenicity,we also incorporated KDO2,a TLR4 agonist,into the lipid bilayer of all nanoliposome formulations.We then conducted in vivo imaging studies in mice and ex vivo cell studies from 2 patient samples who both strongly expressed one of the identified peptides.Results:We demonstrate that these liposomes,loaded with the different melanoma helper peptides,can be readily mixed together and simultaneously delivered without toxicity in vivo.These liposomes are capable of being diffused to the secondary lymphoid organs very quickly and for at least 6 days.In addition,we show that these immunogenic liposomes enhance immune responses to specific peptides ex vivo.Conclusion:Lipid-based delivery systems,including nanoliposomes and lipid nanoparticles,have now been validated for pharmacological(small molecules,bioactive lipids)and molecular(mRNA,siRNA)therapeutic approaches.However,the utility of these formulations as cancer vaccines,delivering antigenic peptides,has not yet achieved the same degree of commercial success.Here,we describe the novel and successful development of a nanoliposome-based cancer vaccine for melanoma.These vaccines help to circumvent drug resistance by increasing a patient’s T cell response,making them more susceptible to checkpoint blockade therapy. | Katelyn E.Salotto Walter C.Olson Jr Karlyn E.Pollack Anuradha Illendula Elishama Michel Sydney Henriques Todd Fox Susan Walker Marya Dunlap-Brown Craig L.Slingluff Jr Mark Kester Helena W.Snyde | 2022 | Cancer Drug Resistance2022，5，3： | 0 |
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