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| 1 | Biodegradation of indole by a newly isolated Cupriavidus sp. SHE显示文摘Indole, a typical nitrogen heterocyclic aromatic pollutant, is extensively spread in industrial wastewater. Microbial degradation has been proven to be a feasible approach to remove indole, whereas the microbial resources are fairly limited. A bacterial strain designated as SHE was isolated and found to be an efficient indole degrader. It was identified as Cupriavidus sp. according to 16 SrRNA gene analysis. Strain SHE could utilize indole as the sole carbon source and almost completely degrade 100 mg/L of indole within 24 hr. It still harbored relatively high indole degradation capacity within p H 4–9 and temperature 25°C–35°C. Experiments also showed that some heavy metals such as Mn2+, Pb2+and Co2+did not pose severe inhibition on indole degradation. Based on high performance liquid chromatography–mass spectrum analysis, isatin was identified as a minor intermediate during the process of indole biodegradation. A major yellow product with m/z 265.0605(C15H8N2O3) was generated and accumulated, suggesting a novel indole conversion pathway existed. Genome analysis of strain SHE indicated that there existed a rich set of oxidoreductases, which might be the key reason for the efficient degradation of indole. The robust degradation ability of strain SHE makes it a promising candidate for the treatment of indole containing wastewater. | Yuanyuan Qu E.Shen Qiao Ma Zhaojing Zhang Ziyan Liu Wenli Shen Jingwei Wang Duanxing Li Huijie Li Jiti Zhou | 2015 | Journal of Environmental Sciences2015，27，8： | 5 |
| 2 | Economic evaluation of cervical cancer screening strategies in urban China显示文摘Objective:This study evaluated the feasibility of different cervical cancer screening strategies in urban China.Methods:A Markov model was constructed to simulate a hypothetical cohort of 100,000 females aged 30-59 years in a 20-year period.Screening strategies included liquid-based cytology(LBC)every three years,human papillomavirus(HPV)DNA testing every three and five years,respectively,and a combination of HPV DNA testing and LBC(HPV+LBC)every three and five years,respectively.Model outcomes included cumulative incidence over 20 years,cumulative risk of cervical cancer,costs,life year saved(LYS),quality-adjusted life years(QALYs)and benefits.The cost-effectiveness ratios(CERs),incremental cost-effectiveness ratios(ICERs),costutility ratios(CURs),and benefit-cost ratios(BCRs)were used as outcomes in the health economic evaluation analysis.Univariate sensitivity analyses were performed to examine the stability of the results.Results:The cumulative incidence of the five screening strategies ranged from 833.02 to 1,158.07 cases per100,000 females.HPV DNA testing was most effective in reducing the cumulative risk of cervical cancer,saving life years and QALYs and gaining benefits.The CERs of HPV DNA testing every three and five years,and LBC every three years were considered to be very cost-effective if they were below China's GDP per capita.The CERs of HPV+LBC were considered to be cost-effective if they were below three times GDP per capita.The incremental cost-effectiveness analysis showed that HPV DNA testing every three and five years,LBC every three years and HPV+LBC every five years were dominant strategies.Conclusions:The findings of this study indicated that HPV DNA testing every five years or LBC every three years should be recommended in urban China. | Li Ma Yuying Wang Xiaohong Gao Yi Dai Yu Zhang Zhaojing Wang Xiaoxia Wang Limin Wang Jing Jiang Xinhua Jing Chunxia Yang Fanghui Zhao Jinghe Lang Youlin Qiao | 2019 | Chinese Journal of Cancer Research2019，31，6： | 4 |
| 3 | Distributed convex optimization for nonlinear multi-agent systems disturbed by a second-order stationary process over a digraph显示文摘In this paper, we investigate the distributed convex optimization problem for a class of nonlinear multi-agent systems disturbed by random noise over a directed graph. The target problem involves designing a continuous-time algorithm to minimize the sum of all local cost functions associated with each agent. The target noise is considered as a second-order stationary process under mild assumptions. The noise-to-state exponential stability for the multi-agent system based on random differential equations is analyzed using a random field method. Sufficient conditions corresponding to the second moment relative to the optimal solution in the form of matrix inequalities are established. Then, the grid search method is employed to determine the best system parameters such that the second moment of the estimation error has the minimum value. In addition, the obtained results are applied to solve the average consensus problem in the presence of a stationary process. Finally, a numerical example is presented to verify the effectiveness of the proposed algorithm. | Dong WANG Zhu WANG Zhaojing WU Wei WANG | 2022 | Science China(Information Sciences)2022，65，3： | 2 |
| 4 | Antioxidant activities of different fractions of polysaccharide purified from Gynostemma pentaphyllum Makino显示文摘 | Zhaojing Wang Dianhui Luo | 2006 | Carbohydrate Polymers2006，，1： | 2 |
| 5 | Optimization of polysac- charides extraction from Gynostemma pentaphyllum Makino using Uni form Design 显示文摘 | Wang Zhaojing Luo Dianhui Cai Ena | 2007 | Carbohydr Polym2007，69，： | 1 |
| 6 | Antioxidant activities of different fractions of polysaccharide purified from Gynostemma pentaphyllum Makino显示文摘 | Luo Dianhui | 2007 | Carbohydrate Polymers2007，68，： | 1 |
| 7 | Positive expression of ERCC1 predicts a poorer platinum-based treatment outcome in Chinese patients with advanced non-small-cell lung cancer显示文摘 | Wang X ZhaoJ Yang L | 2010 | Med On?col2010，27，2： | 1 |
| 8 | the National Natural Science Foundation of China(41877029,41961130383);Royal SocietyNewton Advanced Fellowship(NAF\R1\191017);Wuhan Science and Technology Bureau(2019020701011469).显示文摘Due to the tremendous diversity of microbial organisms in topsoil,the estimation of saturated richness in a belowground ecosystem is still challenging.Here,we intensively surveyed the 16S rRNA gene in four 1 m2 sampling quadrats in a typical grassland,with 141 biological or technical replicates generating over 11 million sequences per quadrat.Through these massive data sets and using both non-asymptotic extrapolation and non-parametric asymptotic approaches,results revealed that roughly 15919±193,27193±1076 and 56985±2347 prokaryotic species inhabited in 1 m2 topsoil,classifying by DADA2,UPARSE(97%cutoff)and Deblur,respectively,and suggested a huge difference among these clustering tools.Nearly 500000 sequences were required to catch 50%species in 1 m2,while any estimator based on 500000 sequences would still lose about a third of total richness.Insufficient sequencing depth will greatly underestimate both observed and estimated richness.At least~911000,~3461000,and~1878000 sequences were needed for DADA2,UPARSE,and Deblur,respectively,to catch 80%species in 1 m2 topsoil,and the numbers of sequences would be nearly twice to three times on this basis to cover 90%richness.In contrast,α-diversity indexes characterized by higher order of Hill numbers,including Shannon entropy and inverse Simpson index,reached saturation with fewer than 100000 sequences,suggesting sequencing depth could be varied greatly when focusing on exploring differentα-diversity characteristics of a microbial community.Our findings were fundamental for microbial studies that provided benchmarks for the extending surveys in large scales of terrestrial ecosystems. | Shuzhen Li Xiongfeng Du Kai Feng Yueni Wu Qing He Zhujun Wang Yangying Liu Danrui Wang Xi Peng Zhaojing Zhang Arthur Escalas Yuanyuan Qu Ye Deng | 2022 | Soil Ecology Letters2022，4，3： | 1 |
| 9 | High-efficiency PERL and PERT silicon solar cells on FZ and MCZ substrates显示文摘 | ZhaoJ H Wang A H Green M A | 2011 | Solar Energy Materials & Solar Cells2011，65，： | 1 |
| 10 | Optimization of polysaccharides extraction from Gynostemma pentaphyllum Makino usingUni form Design显示文摘 | Zhaojing Wang Dianhui Luo Cai Ena | | 0，，： | 1 |
| 11 | Antioxidant activities of different fractions of polysaccharide purified from Gynostemma pentaphyllum Makino显示文摘 | dianhui Luo | 2007 | Carbohydrate Polymers2007，68，： | 1 |
| 12 | Electro-oxidation of glucose at self-assembled monolayers incorporated by copper particles显示文摘 | ZhaoJ Wang F YuJ J | 2006 | Talanta2006，70，： | 1 |
| 13 | Optimization of polysaccharides extraction from gynostemma pentaphyllum makino using uniform design显示文摘 | Wang Zhaojing Luo Dianhui Ena Cai | 2007 | Carbohydrate Polymers2007，69，2： | 1 |
| 14 | Antioxidant activities of different fractions of polysaccharide purified from Gynostemma pentaphyllum Makino显示文摘 | Wang Zhaojing Luo Dianhui | 2007 | Carbohydr Polym2007，68，： | 1 |
| 15 | Interferon-a suppresses invasion and enhances cisplatin-mediated apoptosis and autophagy in human osteosarcoma cells显示文摘 | ZhaoJ Wang M Li Z | 2014 | Oncol Lett2014，7，3： | 1 |
| 16 | Structure of polysaccharides from the fruiting body of Hericium erinaceus Pers 显示文摘 | Wang Zhaojing Luo Dianhui Liang Zhongyan | 2004 | Carbohydrate Polymers2004，57，3： | 1 |
| 17 | Antioxidant activities of different frac- tions of polysaccharide purified from Gynostemma pentaphyllum Makino 显示文摘 | WANG Zhaojing LUO Dianhui | 2007 | Carbohydrate Polymers2007，68，1： | 1 |
| 18 | Structure of polysaccharides from the fruiting body of Hericium erinaceus Pers显示文摘 | WANG Zhaojing LUO Dianhui LIANG Zhongyan | 2004 | Carbohydrate Polymers2004，57，： | 1 |
| 19 | Optimization of polysaccharides extraction from Gynostemma pentaphyllum Makino using uniform design显示文摘 | WANG Zhaojing LUO Dianhui ENA Cai | 2007 | Carbohydrate Polymers2007，69，2： | 1 |
| 20 | B7-H3 and B7-H4 expression in non-small-cell lung cancer显示文摘 | Sun Y Wang Y ZhaoJ | 2006 | Lung Cancer2006，53，2： | 1 |
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