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| 1 | Evaluation of three-dimensional biofilms on antibacterial bonding agents containing novel quaternary ammonium methacrylates显示文摘Antibacterial adhesives are promising to inhibit biofilms and secondary caries.The objectives of this study were to synthesize and incorporate quaternary ammonium methacrylates into adhesives,and investigate the alkyl chain length effects on three-dimensional biofilms adherent on adhesives for the first time.Six quaternary ammonium methacrylates with chain lengths of 3,6,9,12,16 and 18were synthesized and incorporated into Scotchbond Multi-Purpose.Streptococcus mutans bacteria were cultured on resin to form biofilms.Confocal laser scanning microscopy was used to measure biofilm thickness,live/dead volumes and live-bacteria percentage vs.distance from resin surface.Biofilm thickness was the greatest for Scotchbond control;it decreased with increasing chain length,reaching a minimum at chain length 16.Live-biofilm volume had a similar trend.Dead-biofilm volume increased with increasing chain length.The adhesive with chain length 9 had 37%live bacteria near resin surface,but close to 100%live bacteria in the biofilm top section.For chain length 16,there were nearly 0%live bacteria throughout the three-dimensional biofilm.In conclusion,strong antibacterial activity was achieved by adding quaternary ammonium into adhesive,with biofilm thickness and live-biofilm volume decreasing as chain length was increased from 3 to 16.Antibacterial adhesives typically only inhibited bacteria close to its surface;however,adhesive with chain length 16 had mostly dead bacteria in the entire three-dimensional biofilm.Antibacterial adhesive with chain length 16 is promising to inhibit biofilms at the margins and combat secondary caries. | Han Zhou Michael D Weir Joseph M Antonucci Gary E Schumacher Xue-Dong Zhou Hockin H K Xu | 2014 | International Journal of Oral Science2014，6，2： | 5 |
| 2 | Randomised controlled trial of combined spinal epidural vs. spinal anaesthesia for elective caesarean section: vasopressor requirements and cardiovascular changes显示文摘 | Alan JR Macfarlane Artur Pryn Kerry N Litchfield Fiona Bryden Steven Young Christopher Weir Elizabeth M McGrady | 2009 | European Journal of Anaesthesiology2009，，1： | 2 |
| 3 | How plants communicate using the underground information superhighway显示文摘 | Harsh Pal Bais Sang-Wook Park Tiffany L Weir Ragan M Callaway Jorge M Vivanco | 2003 | Trends in Plant Science2003，，1： | 2 |
| 4 | Mircroradiographic characterization of metal and polymer coated microspheres显示文摘 | Singleton R M Weir J T | 1981 | J Vac Sci Technol1981，18，3： | 2 |
| 5 | The effect of timing of dot removal on chronic vasospasm in a primate model显示文摘 | Handa Y Weir BKA Nosko M | 1987 | J Neurosurg1987，67，： | 1 |
| 6 | Prevalence of radiological signs of femoro- aeetabular impingement in patients pres- enting with long-standing adductor-related groin pain显示文摘 | Weir A de Vos R J Moen M | 2011 | Br J Sports Med2011，45，1： | 1 |
| 7 | Annual report to the nation on the status of cancer, 1975 - 2000, featuring the uses of surveillance da- ta for cancer prevention and control 显示文摘 | Weir HK Thun M J Hankey BF | 2003 | Natl Cancer lnst2003，95，17： | 1 |
| 8 | In vitro cultivation of human islet from expanded ductal tissue 显示文摘 | Taneja M Weir GC | 2000 | Proc Natl Acad Sci USA2000，97，14： | 1 |
| 9 | In vitro cultivation of human islets from expanded duetal tissue 显示文摘 | Bonnet-Weir S Taneja M Weir GC | 2000 | Proc Natl Acad Sci USA2000，97，14： | 1 |
| 10 | Effect of clot removal at 24 hours on chronic vasospasm after SAH in the primate model显示文摘 | Nosko M Weir BKA Lamt A | 1987 | J Neurosurg1987，66，： | 1 |
| 11 | Intraspecific and interspecific interactions mediated by a phytotoxin,(-)-catechin,secreted by the roots of Centaurea maculosa显示文摘 | Tiffany L Weir Harsh Pal Bais Jorge M Vivanco | 2003 | Journal of Chemical Ecology2003，29，11： | 1 |
| 12 | Osteogenic media and rhBMP-2-induced differentiation of umbilical cord mesenchymal stem cells encapsulated in alginate microbeads and integrated in an injectable calcium phosphate-chitosan fibrous scaffold显示文摘 | Zhao L Tang M Weir M | | 0，，7： | 1 |
| 13 | Electrostatic Discharge Sensitivity and Electrical Conductivity of Composite Energetic Materials显示文摘 | Weir C Pantoya M L Ramachandran G | | 0，，01： | 1 |
| 14 | Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke显示文摘 | Weir C J Mair S W Waters M R | 2003 | Stroke2003，34，8： | 1 |
| 15 | Biochemical and physiological mechanisms mediated by allelochemicals显示文摘 | Weir T L Park S W Vivanco J M | 2004 | Current Opinion in Plant Biology2004，7，： | 1 |
| 16 | Biochemical and physiologi- cal mechanisms mediated by allelochemicals 显示文摘 | Weir T L Park S W Vivanco J M | 2004 | Curr Opin Plant Biol2004，7，4： | 1 |
| 17 | Gate oxides in 50nm devices: thickness uniformity improves projected reliability 显示文摘 | Weir B E Silverman P J Alam M A | 1999 | Technical Digest -International Electron Devices Meeting1999，，： | 1 |
| 18 | Efficacy tolerability and quality of life of losartan ,alone or with hydrochloro thiazide Versus amlodpine GIIS in patient with essential hypertension显示文摘 | Elkins M liss C | 1996 | Clin ther1996，18，6： | 1 |
| 19 | In vitro cultivation of human islets from expanded ductal tissue 显示文摘 | Bonner-Weir S Taneja M Weir G C | 2000 | Proc Nat Acad Sci USA2000，97，14： | 1 |
| 20 | The tissue renin-angiotensin-aldosterone system in diabetes mellitus显示文摘 | Hanes D S Nahar A Weir M R | 2004 | Cruu Hypertens Rep2004，6，2： | 1 |
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