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| 1 | Nonalcoholic fatty liver disease-A multisystem disease?显示文摘Non-alcoholic fatty liver disease(NAFLD) is one of the most common comorbidities associated with overweight and metabolic syndrome(Met S). Importantly, NAFLD is one of its most dangerous complications because it can lead to severe liver pathologies, including fibrosis, cirrhosis and hepatic cellular carcinoma. Given the increasing worldwide prevalence of obesity, NAFLD has become the most common cause of chronic liver disease and therefore is a major global health problem. Currently, NAFLD is predominantly regarded as a hepatic manifestation of Met S. However, accumulating evidence indicates that the effects of NAFLD extend beyond the liver and are negatively associated with a range of chronic diseases, most notably cardiovascular disease(CVD), diabetes mellitus type 2(T2DM) and chronic kidney disease(CKD). It is becoming increasingly clear that these diseases are the result of the same underlying pathophysiological processes associated with Met S, such as insulin resistance, chronic systemic inflammation and dyslipidemia. As a result, they have been shown to be independent reciprocal risk factors. In addition, recent data have shown that NAFLD actively contributes to aggravation of the pathophysiology of CVD, T2 DM, and CKD, as well as several other pathologies. Thus, NAFLD is a direct cause of many chronic diseases associated with MetS, and better detection and treatment of fatty liver disease is therefore urgently needed. As non-invasive screening methods for liver disease become increasingly available, detection and treatment of NAFLD in patients with MetS should therefore be considered by both(sub-) specialists and primary care physicians. | Ivana Mikolasevic Sandra Milic Tamara Turk Wensveen Ivana Grgic Ivan Jakopcic Davor Stimac Felix Wensveen Lidija Orlic | 2016 | World Journal of Gastroenterology2016，22，43： | 32 |
| 2 | A Critique On The Theory of Financial Intermediation显示文摘 | Bert Scholtens Dick Van Wensveen | 2000 | Journal of Bank&Finance 242000，，： | 1 |
| 3 | Regulation of immune cell function and differentiation by the NKG2D receptor显示文摘 | Zafirova B Wensveen FM Gulin M | 2011 | Cell Mol Life Sci2011，68，21： | 1 |
| 4 | Aesthetic Inter- action:a Framework显示文摘 | LOCHER P OVERBEEKE K WENSVEEN S | 2010 | Design Issues2010，26，2： | 1 |
| 5 | BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis 显示文摘 | Wensveen FM Geest CR Libregts SF | 2013 | Apopto- sis2013，，： | 1 |
| 6 | A Critique on the Theory of Financial Intermediation显示文摘 | | 2000 | Journal of Banking & Finance2000，24，： | 1 |
| 7 | Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinaseprotein kinase B-mammalian target of rapamycin signaling显示文摘 | van de Laar L Buitenhuis M Wensveen FM | | Journal of Immunology0，，： | 1 |
| 8 | Combining HPV and MIB-l tests reduces the number of colposcopies in women with equivocal cytology显示文摘 | Kagie MJ Veldhuizen RW | 2006 | Acta Obstet Gynecol Scand2006，85，12： | 1 |
| 9 | Typhlodromips swirskii (Athias-Henriot) (Acari: Phytoseiidae) : a new predator for thrips control in greenhouse cucumber显示文摘 | Messelink G J van Steenpaal S E F van Wensveen W | 2005 | IOBC/WPRS Bulletin2005，28，1： | 1 |
| 10 | Designing Behavior in Interaction: Using Aesthetic Experience as a Mechanism for Design 显示文摘 | PHILIP R STEPHAN A WENSVEEN G | 2010 | Imernational Journal of Design2010，4，2： | 1 |
| 11 | Typhlodromips swirskii (Athias-Henriot) (Acari:Phytoseiidae):a new predator for thrips control in greenhouse cucumber显示文摘 | Messelink G J Steenpaal S E F Wensveen W | 2005 | IOBC/wprs Bulletin2005，28，1： | 1 |
| 12 | NK cells link obesity-induced adipose stress to inflammation and insulin resistance显示文摘 | WENSVEEN F MJelenClC V Valentif S et ai | 2015 | Nature Immunology2015，16，4： | 1 |
| 13 | Ecosystem Sustainability as a Criterion for Genuine Virtue显示文摘 | Louke van Wensveen | 2001 | Environmental Ethics2001，23，3： | 1 |
| 14 | Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1 显示文摘 | Wensveen FM Alves NL Derks Ingrid AM | 2011 | Apoptosis2011，16，7： | 1 |
| 15 | A critique on the theory of financial intermediation显示文摘 | Scholtens B van Wensveen D | 2000 | Journal of Banking & Financea2000，，24： | 1 |
| 16 | BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis显示文摘 | Wensveen F M Geest C R Libregts S F | 2013 | Apoptosis2013，18，11： | 1 |
| 17 | A critique on the theory of financial intermediation显示文摘 | Scholtens Bert van Wensveen | | 0，，： | 1 |
| 18 | Regulation of immune cell function and differentiation by the NKG2D receptor 显示文摘 | Zafirova B Wensveen FM Gulin M | 2011 | Cell Mol Life Sci2011，68，21： | 1 |
| 19 | CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic Ioad显示文摘 | WENSVEEN F M UNGER P P KRAGTEN N A | | 0，，09： | 1 |
| 20 | Dirty virtues: the emer- gence of ecological virtue ethics显示文摘 | LOUKE VAN WENSVEEN | 2000 | Humanity Books2000，，： | 1 |
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