维普中文期刊产品整合服务
21篇 您的检索式:作者名="WERT G"
    题名 作者 年代 出处 被引量
1Lifestyle-related factors and access to medically assisted reproduction 显示文摘Dondorp W de Wert G Pennings G 2010Hum Reprod2010,25,3:1
2The role of stacking fault energy and induced residual stresses in the sliding wear of aluminum bronze 显示文摘WERT J J SINGGERMAN S A CALDWELL S G etal 1983Wear1983,91,3:1
3Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy显示文摘Diabetic retinopathy(DR)affects approximately one-third of diabetic patients and,if left untreated,progresses to proliferative DR(PDR)with associated vitreous hemorrhage,retinal detachment,iris neovascularization,glaucoma and irreversible blindness.In vitreous samples of human patients with PDR,we found elevated levels of hypoxia inducible factor 1 alpha(HIF1α).HIFs are transcription factors that promote hypoxia adaptation and have important functional roles in a wide range of ischemic and inflammatory diseases.To recreate the human PDR phenotype for a preclinical animal model,we generated a mouse with neuroretinal-specific loss of the von Hippel Lindau tumor suppressor protein,a protein that targets HIF1αfor ubiquitination.We found that the neuroretinal cells in these mice overexpressed HIF1αand developed severe,irreversible ischemic retinopathy that has features of human PDR.Rapid progression of retinopathy in these mutant mice should facilitate the evaluation of therapeutic agents for ischemic and inflammatory blinding disorders.In addition,this model system can be used to manipulate the modulation of the hypoxia signaling pathways,for the treatment of non-ocular ischemic and inflammatory disorders.Katherine J Wert Vinit B Mahajan Lijuan Zhang Yuanqing Yan Yao Li Joaquin Tosi Chun Wei Hsu Takayuki Nagasaki Kerstin M Janisch Maria B Grant MaryAnn Mahajan Alexander G Bassuk Stephen H Tsang 2016Signal Transduction and Targeted Therapy2016,1,1:1
4ESHRE Task Force onEthics and Law 21: genetic screening of gamete donors: ethicalissues显示文摘Dondorp W De Wert G Pennings G 2014Hum Reprod2014,29,7:1
5Oocyte cryopreservation for age-related fertility loss 显示文摘Dondorp W de Wert G Pennings G 2012Hum Reprod2012,27,5:1
6The future (r) evolution of preimplantation genetic diagnosis/human leukocyte antigen testing : ethical reflections 显示文摘de Wert G Liebaers I Van de Velde H 2007Stem Cells2007,25,9:1
7SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production显示文摘Chen G Korfhagen T R Xu Y Kitzmiller J Wert S E Maeda Y 2009J Clin Invest2009,119,:1
8ESHRE task force on ethics and Law22: preimplantation genetic diagnosis显示文摘De Wert G Dondorp W Shenfield F 2014Hum Re- prod2014,29,8:1
9Xml for libraries, archives, and muse- ums: The project covax显示文摘Francisca Herndndez Carlos Wert Ignacio Recio Begofia Aguilera WalterKoch Martin Bogensperg- er Peter Linde Georg G/inter Bob Mulrenin Xavier Agenjo Robin Yeats Luciana Bordoni &Fabrizio Poggi 2003Applied Artificial Intelli- gence2003,17,8:1
10ESHRE Task Force on ethics and Law 20: sex selection for non-medical reasons显示文摘Dondorp W De Wert G Pennings G 2013Hum Reprod2013,28,6:1
11Hereditary surfactant protein B deficiency resulting from a novel mutation显示文摘Somaschini M Wert S Mangili G 2000Intensive Care Med2000,26,1:1
12Oocyte cryopreservation for age 一related fertility loss 显示文摘ESHRE Task Force on Ethics and Law Dondorp W de Wert G 2012Hum Reprod2012,27,5:1
13Acrolein-induced MUC5ac expression in rat airways显示文摘Borchers M T Wert S E Leikauf G D 1998Am J Physiol1998,274,41:1
14Interclass Reliability Estimates : Testing Structural Assumptions 显示文摘Werts C E Linn R L Jreskog K G 1974Education and Psychological Measurement1974,34,1:1
15Innovative reproductive technologies: risks and responsibilities 显示文摘DONDORP W WERT G 2011HumanReport2011,26,7:1
16Acrotein - induced MUC5ac expression in rat airways显示文摘BORCHERS M T WERT S E LEIKAUF G D 1998Am J Physiol1998,274,41:1
17Interclass Reliability Estimates: Testing Structural Assumptions 显示文摘WERTS C E LINN R I JORESKOG K G 1974Educational and Psychological Measurement1974,34,:1
18Hereditary surfactant protein B deficiency resulting from a novel mutation显示文摘 Wert S Mangili G 2000Intensive Care Med2000,26,1:1
19Human embryonic stem cells:research,ethics and policy显示文摘De wert G Mummery C 2003Hum reprod2003,18,4:1
20Human embryonic stem cells: research,ethics and policy 显示文摘de Wert G Mummery C 2003Hum Reprod2003,18,4:1
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费