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	题名	作者	年代	出处	被引量
1	Early prediction of major depression in chronic hepatitis C patients during peg-interferon α-2b treatment by assessment of vegetative-depressive symptoms after four weeks显示文摘AIM: To study the predictive value of the vegetative- depressive symptoms of the Zung Depression Rating Scale for the occurrence of depression during treatment with peg-interferon α-2b of chronic hepatitis C (CHC) patients. METHODS: The predictive value of vegetative- depressive symptoms at 4 wk of treatment for the occurrence of a subsequent diagnosis of major depressive disorder (MDD) was studied in CHC patients infected after substance use in a prospective, multi- center treatment trial in Belgium. The presence of vegetative-depressive symptoms was assessed using the Zung Scale before and 4 wk after the start of antiviral treatment. RESULTS: Out of 49 eligible patients, 19 (39%) developed MDD. The area under the ROC curve of the vegetative Zung subscale was 0.73, P = 0.004. The sensitivity at a cut-point of > 15/35 was 95% (95% CI: 74-100). The positive predictive value equalled 44% (95% CI: 29-60). CONCLUSION: In this group of Belgian CHC patients infected after substance use, antiviral treatment caused a considerable risk of depression. Seven vegetativedepressive symptoms of the Zung scale at wk 4 of treatment predicted 95% of all emerging depressions, at a price of 56% false positive test results.	Geert Robaeys Jozef De Bie Marieke C Wichers Liesbeth Bruckers Frederik Nevens Peter Michielsen Marc Van Ranst Frank Buntinx	2007	World Journal of Gastroenterology2007，13，43：	4
2	The role of indoleamine 2,3-dioxygenase (IDO) in the Pathophysiology of interferon-alpha-induced depression显示文摘	Wichers M C Maes M	2004	J Psychiatry Neurosci2004，29，1：	1
3	Enteric infection with an obligate intracellular parasite, Encephalitozoon cunicull,in an experimental model显示文摘	Wicher V Baughn R E Fuentealba I C	1991	Infect Immun1991，59，2：	1
4	Cytokines and major depression 显示文摘	Schiepers O J Wichers M C Maes M	2005	Prog Neuropsychopharmacol Biol Psychiatry2005，29，2：	1
5	Characterization of the total free radical scavenging capacity of vegetable oils and oil fractions u- sing 2,2 - diphenyl - 1 - picryl hydrazyl radical 显示文摘	Espin J C Soler - Rivas C Wichers H J	2000	Journal of Ag- ricultural and Food Chemistly2000，48，：	1
6	Sequence and structural features of plant and fungal tyrosinases 显示文摘	Van Gelder C W G FLURKEY W H WICHERS H J	1997	Phytochemistry1997，45，7：	1
7	PPO activity and polyphenol content are not limiting factors during brown core development in pears (Pyrus communis 'Conference' )显示文摘	ELTMAN R H LARRIGAUDIERE C WICHERS H	1999	Plant Physiol1999，154，：	1
8	Intrapefitoneal influx of neutrophils in response to IL-33 is mast cell-dependent显示文摘	Enoksson M Mtiller-Westerberg C Wicher G	2013	Blood2013，121，3：	1
9	Fetal body weight and the development of the control ol the cardiovascular system in fetal sheep 显示文摘	Frasch MG Muller T Wicher C	2007	J Physiol2007，579，3：	1
10	Antiinflammatory and immunomodulating properties of fungal metabolites显示文摘	Lull C Wichers H Savelkoul H	2005	Mediators Inflamm2005，2，：	1
11	Fetal body weight and the development of the control of the cardiovascular system in fetal sheep显示文摘	Frasch MG Muller T Wicher C	2007	J Physio12007，579，3：	1
12	Evidence that moment- tmoment variation in positive emotions buffer genetic risk for depression:a momentary assessment twin study显示文摘	Wichers M C Myin Germeys I Jacobs N	2007	Acta Psychiatr Scand2007，115，6：	1
13	Sequenceand structural features of plant and fungal tyrosinases显示文摘	Van Gelder C W Flurkey W H Wichers H J	1997	Phytochemistry1997，45，7：	1
14	Impact of (bio)chemical and physical procedures on food allergen stability显示文摘	Soler-Rivas C Wichers H J	2001	Allergy2001，53，67：	1
15	AntiIFN lammatory and immunomodulating properties of fungal metabolites显示文摘	Lull C Wichers HJ Savelkoul H F	2005	Mediator of IFN lammatio2005，2，：	1
16	Fetal body weight and the development of the control of the cardiovascular system in fetal sheep显示文摘	Frasch MG Mtiller T Wicher C	2007	J Physiol2007，579，3：	1
17	Sequence and structural features of plant and fungal tyrosinases显示文摘	Van Gelder C W Flurkey W H Wichers H J	1997	Phytochemistry1997，45，7：	1
18	Fetal body weight and the development of the control of the cardiovas- cular system in fetal sheep 显示文摘	Frasch MG Mtiller T Wicher C	2007	J Physiol2007，579，3：	1
19	Fetal body weight and the development of the control of the cardiovascular system in fetal sheep显示文摘	FRASCH M G MIIILER T WICHER C	2007	J Physiol2007，579，3：	1
20	Poly- phenol oxidase activity and polyphenol content are not limiting factors during brown core development in pears显示文摘	VELTMAN R H LARRIGAUDIeRE C WICHERS H J	1999	Plant Physiol1999，154，：	1

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