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1China Stroke Statistics 2019:A Report From the National Center for Healthcare Quality Management in Neurological Diseases,China National Clinical Research Center for Neurological Diseases,the Chinese Stroke Association,National Center for Chronic and Non-communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention and Institute for Global Neuroscience and Stroke Collaborations显示文摘China faces the greatest challenge from stroke in the world.The death rate for cerebrovascular diseases in China was 149.49 per 100000,accounting for 1.57 million deaths in 2018.It ranked third among the leading causes of death behind malignant tumours and heart disease.The age-standardised prevalence and incidence of stroke in 2013 were 1114.8 per 100000 population and 246.8 per 100000 person-years,respectively.According to the Global Burden of Disease Study 2017,the years of life lost(YLLs)per 100000 population for stroke increased by 14.6%;YLLs due to stroke rose from third highest among all causes in 1990 to the highest in 2017.The absolute numbers and rates per 100000 population for all-age disability-adjusted life years(DALYs)for stroke increased substantially between 1990 and 2017,and stroke was the leading cause of all-age DALYs in 2017.The main contributors to cerebrovascular diseases include behavioural risk factors(smoking and alcohol use)and pre-existing conditions(hypertension,diabetes mellitus,dyslipidaemia and atrial fibrillation(AF)).The most prevalent risk factors among stroke survivors were hypertension(63.0%-84.2%)and smoking(31.7%-47.6%).The least prevalent was AF(2.7%-7.4%).The prevalences for major risk factors for stroke are high and most have increased over time.Based on the latest national epidemiological data,26.6%of adults aged≥15 years(307.6 million adults)smoked tobacco products.For those aged≥18 years,age-adjusted prevalence of hypertension was 25.2%;adjusted prevalence of hypercholesterolaemia was 5.8%;and the standardised prevalence of diabetes was 10.9%.For those aged≥40 years,the standardised prevalence of AF was 2.31%.Data from the Hospital Quality Monitoring System showed that 3010204 inpatients with stroke were admitted to 1853 tertiary care hospitals during 2018.Of those,2466785(81.9%)were ischaemic strokes(ISs);447609(14.9%)were intracerebral haemorrhages(ICHs);and 95810(3.2%)were subarachnoid haemorrhages(SAHs).The average age of patients admitted was 66 years old,and nearly 60%were male.A total of 1555(0.1%),2774(0.6%)and 1347(1.4%)paediatric strokes(age<18 years)were identified among IS,ICH and SAH,respectively.Over one-third(1063892(35.3%))of the patients were covered by urban resident basic medical insurance,followed by urban employee basic medical insurance(699513(23.2%))and new rural cooperative medical schema(489361(16.3%)).The leading risk factor was hypertension(67.4%for IS,77.2%for ICH and 49.1%for SAH),and the leading comorbidity was pneumonia or pulmonary infection(10.1%for IS,31.4%for ICH and 25.2%for SAH).In-hospital death/discharge against medical advice rate was 8.3%for stroke inpatients,ranging from 5.8%for IS to 19.5%for ICH.The median and IQR of length of stay was 10.0(7.0-14.0)days,ranging from 10.0(7.0-13.0)in IS to 14.0(8.0-22.0)in SAH.Data from the Chinese Stroke Center Alliance demonstrated that the composite scores of guideline-recommended key performance indicators for patients with IS,ICH and SAH were 0.77±0.21,0.72±0.28 and 0.59±0.32,respectively.Yong-Jun Wang Zi-Xiao Li Hong-Qiu Gu Yi Zhai Yong Jiang Xing-Quan Zhao Yi-Long Wang Xin Yang Chun-Juan Wang Xia Meng Hao Li Li-Ping Liu Jing Jing Jing Wu An-Ding Xu Qiang Dong David Wang Ji-Zong Zhao On behalf of China Stroke Statistics 2019 Writing Committee 2020Stroke & Vascular Neurology2020,5,3:181
2Interpretation of Annual Report on Cardiovascular Health and Diseases in China 2019显示文摘The Chinese edition of Annual Report on Cardiovascular Health and Diseases in China 2019 have been published[1],and we present herein an interpretation of the report.Influencing factors on cardiovascular health Tobacco use The smoking prevalence among Chinese residents has shown a downward trend.According to the Chinese Adult Tobacco Survey in 2018,the current smoking prevalence among Chinese residents≥15years of age was 26.6%,which was higher in rural areas(28.9%)than in urban areas(25.1%),and the daily consumption by each smoker was 16.0 cigarettes on average.The Writing Committee of the Annual Report on Cardiovascular Health and Diseases in China Zengwu Wang Shengshou Hu 2021Cardiology Discovery2021,1,4:7
3Report on cardiovascular health and diseases in China 2021: an updated summary显示文摘In 2019,cardiovascular disease(CVD)accounted for 46.74%and 44.26%of all deaths in rural and urban areas,respectively.Two out of every five deaths were attributed to CVD.It is estimated that approximately 330 million individuals in China are affected by CVD.Among them,there are 13 million cases of stroke,11.4 million cases of coronary heart disease,5 million cases of pulmonary heart disease,8.9 million cases of heart failure,4.9 million cases of atrial fibrillation,2.5 million cases of rheumatic heart disease,2 million cases of congenital heart disease,45.3 million cases of lower extremity artery disease,and 245 million cases of hypertension.With the dual challenges of population aging and a steady increase in the prevalence of metabolic risk factors,the burden of CVD in China is expected to continue rising.Consequently,new demands arise for CVD prevention,treatment,and the allocation of medical resources.Emphasizing primary prevention to reduce disease prevalence,increasing the allocation of medical resources for CVD emergency and critical care,and providing rehabilitation services and secondary prevention to reduce the risk of recurrence,rehospitalization,and disability among CVD survivors are of paramount importance.Hypertension,dyslipidemia,and diabetes affect millions of individuals in China.Since blood pressure,blood lipids,and blood sugar levels often rise insidiously,vascular disease and serious events such as myocardial infarction and stroke occur by the time they are detected in this population.Therefore,it is crucial to implement strategies and measures to prevent risk factors such as hypertension,dyslipidemia,diabetes,obesity,and smoking.Furthermore,greater efforts should be directed towards assessing cardiovascular health status and conducting research on early pathological changes to enhance prevention,treatment,and understanding of CVD.The Writing Committee of the Report on Cardiovascular Health and Diseases in China Sheng-Shou HU 2023Journal of Geriatric Cardiology2023,20,6:5
4Report on Cardiovascular Health and Diseases in China 2022:an Updated Summary显示文摘In the past 30 years,the accessibility and quality index of medical care have made remarkable progress in China,ranking the first among middle-income countries.Many cardiovascular technologies are at or near the world's leading level,and significant progress has been achieved in China solving the problem of“treatment difficulty”of cardiovascular diseases(CVD).However,due to the prevalence of unhealthy lifestyles among Chinese residents,a huge population with CVD risk factors,accelerated population aging,and other reasons,the incidence and mortality rate of CVD are still increasing,and the turning point of the decline in disease burden has not appeared yet in China.In terms of proportions of disease mortality among urban and rural residents,CVD still ranks the first.In 2020,CVD accounted for 48.00%and 45.86%of the causes of death in rural and urban areas,respectively;two out of every five deaths were due to CVD.It is estimated that the number of current CVD patients in China is around 330 million,including 13 million stroke,11.39 million coronary heart disease,8.9 million heart failure,5 million pulmonary heart disease,4.87 million atrial fibrillation,2.5 million rheumatic heart disease,2 million congenital heart disease,45.3 million peripheral artery disease,and 245 million hypertension cases.China has entered a new stage of transformation from high-speed development to high-quality development,and the prevention and control of CVD in China should also shift from previous emphasis on scale growth to strategies focusing more on strategic and key technological development in order to curb the trend of increasing incidence and mortality rates of CVD.The Writing Committee of the Report on Cardiovascular Health and Diseases in China 2023Biomedical and Environmental Sciences2023,36,8:4
5Chinese expert consensus on the diagnosis of cardiogenic stroke(2019)显示文摘Cardioembolic stroke(CES),also known as cardiogenic stroke,refers to a clinical syndrome caused by a cardiogenic embolus from the heart,leading to cerebral artery embolism through circulation,and it consequently results in corresponding brain dysfunction.CES is associated with greater severity,poor outcomes,and a relatively high recurrence rate,compared with other subtypes of ischemic stroke.Guang-Zhi Liu Rong Hu Dan-Tao Peng Geriatric Neurology Grop,Geriatric Branch of Chinese Medical Association Writing Group of Chinese expert consensus on diagnosis of cardiogenic stroke 2021Chinese Medical Journal2021,,5:3
6Clinical guideline on topical growth factors for skin wounds显示文摘An increased number of patients with skin wounds have been witnessed in the past decades.Among the various kinds of treatments for skin wounds,topical exogenous growth factors are indispensable and have been used in many countries.However,whether they have reliable effects remains controversial,and their application for skin wound treatment needs to be further standardized and optimized in terms of socio-economic considerations.Thus,the Chinese Burn Association developed this guideline indicating efficacy,application details,adverse reactions and precautions of five clinically common topical growth factors using the Grading of Recommendations Assessment Development and Evaluation method to promote the rational application of topical exogenous growth factors in skin wounds and to benefit more patients.Chun-mao Han Biao Cheng PanWu writing group of growth factor guideline on behalf of Chinese Burn Association 2020Burns & Trauma2020,8,1:2
7ACC/ AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction:Executive Summary 显示文摘A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) 2007Circulation2007,116,:1
8Clinical policy: critical issues in the evaluation and management of adult patients with asymptomatic hypertension in the emergency department 显示文摘Decker WW Godwin SA Hess EP Lenamond CC Jagoda AS American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Asymptomatie Hypertension in the ED 2006Ann Emerg Med2006,47,:1
9Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W) : a randomised controlled trial显示文摘ACTIVE Writing Group on behalf of the ACTIVE Investigators 2006Lancet2006,367,9526:1
10Avian influenza A (H5N1) infection in humans 显示文摘The Writing Committee of the World Health Organization on Human influenza A/H5 2005N Engl J Med2005,353,13:1
11Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the atrial fibrillation clopidogrel trial with Irbesartan for prevention of vascular events (ACTIVE-W):a randomized controlled trial显示文摘ACTIVE Writing Group on behalf of the ACTIVE Investigators 0,,9526:1
12ACC/AHA2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery:executive summary:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines(Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery)显示文摘American College of Cardiology/American Heart Association Task Force on Practice Guidelines(Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) American Society of Echocardiography American Society of Nuclear Cardiology 2008Anesth Analg2008,106,3:1
13Clinical aspects of Pandemic 2009 Influenza A(H 1N 1 )virus infection 显示文摘Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H 1N 1 ) 2009 Influenza Bautista E Chotpitayasunondh T 2009N Engl J Med2009,362,18:1
14Avian influenza (H5N1)infection in humans显示文摘The Writing Committee of the World Health Organization consulation on Human influenza A/H5N1 2005New England Journal of Medicine2005,353,:1
15Update on avian in-fluenza A(H5N1)virus infection in humans显示文摘Writing Committee of the Second World Health Organ-ization Consultation on Clinical Aspects of HumanInfection with Avian Influenza A Virus Abdel-GhafarA N Chotpitayasunondh T 2008NEngl J Med2008,358,3:1
16Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events ( ACTIVE W) : a randomised controlled trial显示文摘ACTIVE Writing Group on behalf of the ACTIVE Investigators 2006Lancet2006,367,:1
17Guidelines for the diagnosis of rheumatic fever:Jones Criteria(1992 update)显示文摘Special Writing Group of the Committee on Rheumatic Fever Endocarditis and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association 1992JAMA1992,268,15:1
18Standardized Myocardial Segmentation and Nomenclature for Tomographic Imaging of the Heart:A Statement for Healthcare Professionals From the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association显示文摘American Heart Association Writing Group on Myocardial Segmenta- tion and Registration for Cardiac Imaging 2002Circulation2002,105,:1
19The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis 显示文摘XIN L LAWSON DA WRITE ON 2005Proc Natl Acad Sci USA2005,102,19:1
20Guidelines for the diagnosis of rheumatic fever: Jnnes criteria: 1992 update显示文摘 Endccarditis and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association 1992JMAM1992,268,:1
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