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| 1 | A_r-Weighted Poincare-Type Inequalities for Differential Forms in Some Domains | Shu Sen DING Department of Mathematics. Seattle University, 900 Broadway, Seattle. WA 98122, USA Yun Ying GAI Department of Mathematics, Harbin Institute of Technology, Harbin. 150001, P. R. China | 2001 | Acta Mathematica Sinica,English Series2001，17，2： | 5 |
| 2 | Nanostructured Catalyst for Fischer-Tropsch Synthesis显示文摘 | Wa Gao Qingshan Zhu Ding Ma | 2018 | Chinese Journal of Chemistry2018，36，9： | 2 |
| 3 | Influence of the geometry of the left main coronary artery bifurcation on the distribution of sudanophilia in the daughter vessels显示文摘 | Ding Z Biggs T Seed WA | 1997 | Arterioscler Thromb Vasc Biol1997，17，： | 1 |
| 4 | Expression of endothelial leukocyte adhesion molecule- 1 in septic but not traumatic/hypovolemic shock in baboon显示文摘 | Redl H Dinges HP Buurman WA | 1991 | Am J Pathol1991，139，： | 1 |
| 5 | Evaluating causal rela- tions in neural systems: granger causality, directed transfer function and statistical assessment of significance显示文摘 | Kaminski M Ding M Truccolo WA | 2001 | Biol Cybern2001，85，2： | 1 |
| 6 | Evaluating causal relations in neural systems: granger causality, directed transfer function and statistical assessment of significance显示文摘 | Kaminski M Ding M Truccolo WA | 2001 | BioI Cybern2001，85，2： | 1 |
| 7 | TriM-to-trial variability of conical evoked responses: Implications for the analysis of functional eonnectivity显示文摘 | Truccolo WA Ding M Knuth KH | 2002 | Clin Neurophysiol2002，113，2： | 1 |
| 8 | Refractive indices of human skin tissues at eight wave- lengths and estimated dispersion rel- ations betwwen 300 and 1 600 nm显示文摘 | Ding H Lu JQ Wooden WA et ol | 2006 | Phys Med Biol2006，51，6： | 1 |
| 9 | Expression of endothelia leukocyte adhesion molecule-1 in septic but not traumatic/hypovolemic shock in the baboon 显示文摘 | Redl H Dinges HP Buurman WA | 1991 | Am J Pathol1991，139，： | 1 |
| 10 | Trial-to-trial variability of cortical evoked responses: Implications for the analysis of functional connectivity 显示文摘 | Truccolo WA Ding MZ Knuth KH | 2002 | Clin Neurophysiol2002，113，： | 1 |
| 11 | Breeding wheat for resistance to insects显示文摘 | Berzonsky WA Ding H Haley SD | | 0，，： | 1 |
| 12 | Influence of thegeometry of the left main coronary artery bifurcation on the distribution of sudanophilia in the daughter vessels 显示文摘 | Ding Zhaohua Biggs T Seed WA | 1997 | Arterioscler Thromb Vasc Biol1997，17，7： | 1 |
| 13 | Expression of endothelia leukocyte adhesion molecule-1 in septic but not traumatic/hypovolemic shock in the baboon显示文摘 | Dinges HP Buurman WA | 1991 | Am J Pathol1991，139，2： | 1 |
| 14 | Trial-to-trial variability of cortical evoked responses: implications for the analysis of functional Connectivity 显示文摘 | Truccolo WA Ding M Knuth KH | 2002 | Clin Neurophysiol2002，113，2： | 1 |
| 15 | Trial-to-trial variability of cortical evoked responses:implications for the analysis of functional connectivity显示文摘 | Truccolo WA Ding MZ Knuth KH | 2002 | Clin Neurophysio12002，113，： | 1 |
| 16 | Advances in photothermal conversion of carbon dioxide to solar fuels显示文摘Converting carbon dioxide(CO_(2)) into useful fuels or chemical feedstocks is important for achieving peak carbon emission and carbon neutrality.Recently,photothermal catalysis has been extensively studied and applied due to its advantages over traditional heat-driven catalysis.In this review,we focus on photothermal catalysis of thermodynamically uphill reactions that convert CO_(2)into value-added products.We first introduce the fundamentals of photothermal catalysis for CO_(2)reduction,including the definition and classification of photothermal catalysis,followed by their photothermal conversion processes.The structure design of different types of photothermal catalysts is summarized.The superior performance of photothermal catalytic conversion of CO_(2)is illustrated and discussed,including improved CO_(2)activation,tunable selectivity towards different solar fuel products,and resistance to sintering and coking.Finally,the perspectives and challenges in this cutting-edge field are presented with the aim of advancing understanding of the underlying mechanisms and inspiring rational design of photothermal catalysts for highly efficient solar-to-fuel conversion. | Wa Gao Yinwen Li Dequan Xiao Ding Ma | 2023 | Journal of Energy Chemistry2023，，8： | 0 |
| 17 | Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells显示文摘5-Fluorouracil(5-FU)is the first-line treatment for colorectal cancer(CRC)patients,but the development of acquired resistance to 5-FU remains a big challenge.Deubiquitinases play a key role in the protein degradation pathway,which is involved in cancer development and chemotherapy resistance.In this study,we investigated the effects of targeted inhibition of the proteasomal deubiquitinases USP14 and UCHL5 on the development of CRC and resistance to 5-FU.By analyzing GEO datasets,we found that the mRNA expression levels of USP14 and UCHL5 in CRC tissues were significantly increased,and negatively correlated with the survival of CRC patients.Knockdown of both USP14 and UCHL5 led to increased 5-FU sensitivity in 5-FU-resistant CRC cell lines(RKO-R and HCT-15R),whereas overexpression of USP14 and UCHL5 in 5-FU-sensitive CRC cells decreased 5-FU sensitivity.B-AP15,a specific inhibitor of USP14 and UCHL5,(1−5μM)dose-dependently inhibited the viability of RKO,RKO-R,HCT-15,and HCT-15R cells.Furthermore,treatment with b-AP15 reduced the malignant phenotype of CRC cells including cell proliferation and migration,and induced cell death in both 5-FU-sensitive and 5-FU-resistant CRC cells by impairing proteasome function and increasing reactive oxygen species(ROS)production.In addition,b-AP15 inhibited the activation of NF-κB pathway,suppressing cell proliferation.In 5-FU-sensitive and 5-FU-resistant CRC xenografts nude mice,administration of b-AP15(8 mg·kg^(-1)·d^(-1),intraperitoneal injection)effectively suppressed the growth of both types of tumors.These results demonstrate that USP14 and UCHL5 play an important role in the development of CRC and resistance to 5-FU.Targeting USP14 and UCHL5 with b-AP15 may represent a promising therapeutic strategy for the treatment of CRC. | Wa Ding Jin-xiang Wang Jun-zheng Wu Ao-chu Liu Li-ling Jiang Hai-chuan Zhang Yi Meng Bing-yuan Liu Guan-jie Peng En-zhe Lou Qiong Mao Huan Zhou Dao-lin Tang Xin Chen Jin-bao Liu Xian-ping Shi | 2023 | Acta Pharmacologica Sinica2023，44，12： | 0 |
| 18 | Stabilization of MYC G-quadruplex DNA by ruthenium(II)complex overcomes imatinib resistance in chronic myeloid leukemia cells harboring T315I mutation显示文摘The key pathogenesis of chronic myeloid leukemia(CML)is the formation of BCR-ABL fusion gene,encoding a 210 kDa Bcr-Abl tyrosine kinase,which is crucial for the occurrence and development of CML.Imatinib(IM)is the first targeted anticancer drug approved by FDA for the treatment of CML;however,some patients,especially those in accelerated phase and blastic phase,develop primary or secondary drug resistance to IM.Particularly,the most challenging resistance is caused by T315I mutation of Bcr-Abl,which represents approximately 15%–20%of all acquired mutations and renders cell resistant to a variety of tyrosine kinase inhibitors.1,2 Thus,there is an urgent need to develop novel strategies to overcome Bcr-Abl T315I-meidated IM resistance. | Yuening Sun Xin Chen Siyan Liao Aochu Liu Huan Zhou Liling Jiang Wa Ding Wenjie Mei Jinbao Liu Xianping Shi | 2023 | Genes & Diseases2023，10，2： | 0 |
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