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| 1 | Balloon-occluded retrograde transvenous obliteration for treatment of gastric varices显示文摘Rupture of gastric varices(GVs)can be fatal.Balloon-occluded retrograde transvenous obliteration(BRTO),as known as retrograde sclerotherapy,has been widely adopted for treatment of GVs because of its effectiveness,ability to cure,and utility in emergency and prophylactic treatment.Simplifying the route of blood flow from GVs to the gastrorenal shunt is important for the successful BRTO.This review outlines BRTO indications and contraindications,describes basic BRTO procedures and modifications,compares BRTO with other GVs treatments,and discusses various combination therapies.Combined BRTO and partial splenic embolization may prevent exacerbation of esophageal varices and shows promise as a treatment option. | Nobuo Waguri Akihiko Osaki Yusuke Watanabe | 2021 | World Journal of Hepatology2021，13，6： | 6 |
| 2 | Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis显示文摘 | Nitatori T Sato N Waguri S | 1995 | J Neurosci1995，15，： | 2 |
| 3 | 显示出与肝炎 B 病毒感染联系的微分表示的细胞的基因的鉴定显示文摘 AIM: To investigate the impact of hepatitis B virus (HBV) infection on cellular gene expression, by conducting both in vitro and in vivo studies. METHODS: Knockdown of HBV was targeted by stable expression of short hairpin RNA (shRNA) in huH-1 cells. Cellular gene expression was compared using a human 30K cDNA microarray in the cells and quantified by real-time reverse transcription-polymerase chain reaction (RT-PCR) (qRT-PCR) in the cells, hepatocellular carcinoma (HCC) and surrounding non-cancerous liver tissues (SL). RESULTS: The expressions of HBsAg and HBx protein were markedly suppressed in the cells and in HBx transgenic mouse liver, respectively, after introduction of shRNA. Of the 30K genes studied, 135 and 103 genes were identified as being down- and up-regulated, respectively, by at least twofold in the knockdown cells. Functional annotation revealed that 85 and 62 genes were classified into four up-regulated and five down-regulated functional categories, respectively. When gene expression levels were compared between HCC and SL, eight candidate genes that were confirmed to be up- or down-regulated in the knockdown cells by both microarray and qRT-PCR analyses were not expressed as expected from HBV reduction in HCC, but had similar expression patterns in HBV- and hepatitis C virus-associated cases. In contrast, among the eight genes, only APM2 was constantly repressed in HBV non-associated tissues irrespective of HCC or SL. | Yasuo Fukuhara Takeshi Suda Makoto Kobayashi Yasushi Tamura Masato Igarashi Nobuo Waguri Hirokazu Kawai Yutaka Aoyagi | 2012 | World Journal of Hepatology2012，4，4： | 2 |
| 4 | Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis 显示文摘 | Nitatori T Sato N Waguri S | 1995 | J Neurosci1995，15，2： | 1 |
| 5 | Impairment of starvationinduced and constitutive autophagy in Atg7-deficient mice显示文摘 | Komatsu M Waguri S Ueno T | 2005 | J Cell Biol2005，169，3： | 1 |
| 6 | Persistent activation of Nrf2through p62 in hepatocellular carcinoma cells显示文摘 | Inami Y Waguri S Sakamoto A | 2011 | J Cell Biol2011，193，2： | 1 |
| 7 | Delayed neuronal death in the CA1pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis显示文摘 | Nitatori T Sato N Waguri S | 1995 | J Neurosci1995，15，2： | 1 |
| 8 | Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ische- mia is apoptosis显示文摘 | Nitaton T Sato N Waguri S | 2005 | J Neurosci2005，25，： | 1 |
| 9 | Epidural blood patch for treatment of spontaneous intracranial hypotension显示文摘 | Tomita M Hayatsu K | 2002 | Acta Anaesthesiol Scand2002，46，6： | 1 |
| 10 | Impairment of starvation-in-duced and constitutive autophagy in Atg7-deficient mice显示文摘 | Komatsu M Waguri S Ueno T | 2005 | J Cell Biol2005，169，3： | 1 |
| 11 | Loss of autophagy in the central nervous system causes neurodegeneration in mice显示文摘 | Komatsu M Waguri S Chiba T | 2006 | Nature2006，441，7095： | 1 |
| 12 | Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis 显示文摘 | Nitatori T Sato N Waguri S | 1995 | J Neurosci1995，15，： | 1 |
| 13 | Loss of autophagy in the central nervous system causes neurodegeneration in mice 显示文摘 | Komatsu M Waguri S Chiba T | 2006 | Nature2006，441，7095： | 1 |
| 14 | Loss of autophagy in the central nervous system causes neurodegeneration in mice 显示文摘 | Komatsu M Waguri S Chiba T | 2006 | Nature2006，441，： | 1 |
| 15 | Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptoais 显示文摘 | Nitatori T Sato N Waguri S | 1995 | J Neurochir1995，15，： | 1 |
| 16 | Autophagy-deficient mice develop multiple liver tumors显示文摘 | Takamura A Komatsu M Hara T Sakamoto A Kishi C Waguri S Eishi Y Hino O Tanaka | | 0，，08： | 1 |
| 17 | The Atg8 conjugation sys- tem is indispensable for proper development of autophagic iso- lation membranes in mice显示文摘 | Sou Y S Waguri S Iwata J | 2008 | Mol Biol Cell2008，19，11： | 1 |
| 18 | The selective autophagy substrate p62 activates the stress responsive transcription factor NRF2 through inactivation of KEAP1显示文摘 | Komatsu M Kurokawa H Waguri S | 2010 | Nat Cell Biol2010，12，3： | 1 |
| 19 | Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice显示文摘 | Komatsu M Waguri S Koike M | | 0，，6： | 1 |
| 20 | Epidural blood patch fortreatment of spontaneous intracranial hypotension 显示文摘 | Waguri N Tomita M Hayatsu K | 2002 | Acta Anaes-thesiol Scand2002，46，6： | 1 |
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