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| 1 | A randomized trial comparing the Tennant Biomodulator to transcutaneous electrical nerve stimulation and traditional Chinese acupuncture for the treatment of chronic pain in military service members显示文摘Background:The present investigation tested the efficacy of the Tennant Biomodulator,a novel pain management intervention that uses biofeedback-modulated electrical stimulation,to reduce chronic pain and its psychosocial sequelae in a sample of current and former military service members.The Tennant Biomodulator used on its most basic setting was compared to two commonly used,non-pharmacological pain treatments—traditional Chinese acupuncture and transcutaneous electrical nerve stimulation(TENS)—in a comparative efficacy,randomized,open-label trial.Methods:Participants included 100 active duty and retired service men and women with chronic pain undergoing treatment at the Brooke Army Medical Center in Texas,USA,randomly assigned to receive six,weekly sessions of either Tennant Biomodulator treatment,traditional Chinese acupuncture,or TENS,in addition to usual care.Recruitment was conducted between May 2010 to September 2013.Outcome measures were collected at intake,before and after each treatment session,and at a 1-month follow-up.Intent-to-treat analyses were used throughout,with mixed models used to investigate main effects of group,time,and group×time interactions with consideration given to quadratic effects.Outcomes measured included ratings of chronic pain,pain-related functional disability,and symptoms of post-traumatic stress disorder(PTSD)and depression.Results:On average,regardless of their treatment group,participants exhibited a 16%reduction in pain measured by the Brooke Army Medical Center’s Clinic Pain Log[F(1,335)=55.7,P<0.0001]and an 11%reduction in pain-related disability measured by the Million Visual Analog Scale[MVAS:F(1,84)=28.3,P<0.0001]from baseline to the end of treatment,but no one treatment performed better than the other,and the reductions in pain and pain-related disability were largely lost by 1-month follow-up.Symptoms of PTSD and depression did not change significantly as a function of time or group.Conclusions:Findings build on previous work suggesting that traditional Chinese acupuncture and TENS can reduce pain and its functional sequelae without risks associated with pharmacological pain management.The Tennant Biomodulator used on its most basic setting performs as well as these other interventions.Based on the present findings,large,randomized controlled trials on the Tennant Biomodulator are indicated.Future work should test this device using its full range of settings for pain-related psychological health.Trial registration:Clincialtrials.gov(NCT01752010);registered December 14,2012. | Kimberly S.Peacock Erika Stoerkel Salvatore Libretto Weimin Zhang Alice Inman Michael Schlicher John D.Cowsar Jr David Eddie Joan Walter | 2020 | Military Medical Research2020，7，2： | 3 |
| 2 | Multisystem immunologically mediated disease:T lymphocyte deficiency and thyroid immunologic disease-A report of four cases显示文摘 | Wall JR Fang SL Walters BA | 1978 | Aust NZ J Med1978，8，3： | 1 |
| 3 | Current perspectives on the treatment of idiopathic pulmonary fibrosis显示文摘 | Walter N Collard HR King TE Jr | 2006 | Proc Am Thorac Soc2006，3，4： | 1 |
| 4 | QIIME allows analysis of high-throughput community sequencing data 显示文摘 | Caporaso JG Kuczynski J Stombaugh J Bittinger K Bushman FD Costello EK Fierer N Pena AG Goodrich JK Gordon JI Huttley GA Kelley ST Knights D Koenig JE Ley RE Lozupone CA Mcdonald D Muegge BD Pirrung M Reeder J Sevinsky JR Tumbaugh PJ Walters WA Widmann J Yatsunenko T Zaneveld J Knight R | 2010 | Nat Methods2010，7，5： | 1 |
| 5 | BAFF and MyD88 signals promote a lupuslike disease independent of T cells显示文摘 | Groom JR Fletcher CA Walters SN | | 0，，08： | 1 |
| 6 | Steepest descent using smoothed gradients显示文摘 | Richardson Jr Walter B | 2000 | Applied Mathematics and computation2000，112，23： | 1 |
| 7 | StklO, a new member of the polo-like kinase family highly expressed in hematopoietic tissue 显示文摘 | Walter S A Cutler R E Jr Martinez R | 2003 | J Biol Chem2003，278，18： | 1 |
| 8 | Effect of solids concentration on the sorption partitioning of hydrophobic pollutants in aquatic systems显示文摘 | THOMAS C V CLIFFORD P R WALTER J W Jr | 1983 | Environmental Science Technology1983，17，9： | 1 |
| 9 | Evidence for a second crystal form of polypropylene显示文摘 | Keith H D Padden F J Jr Walter N M | 1959 | Appl Phys1959，30，： | 1 |
| 10 | Current perspectives on the treatment of idiopathic pulmonary fibrosis 显示文摘 | Walter N Collard HR King TE Jr | 2006 | Proc Am Thorac Soc2006，3，4： | 1 |
| 11 | Bile acid diarrhoea and FGF19:new views on diagnosis,pathogenesis and therapy显示文摘 | Walters JR | 2014 | Nat Rev Gastroenterol Hepatol2014，11，7： | 1 |
| 12 | Friedel-Crafts reactions anisole with acetic anhydride over HPW/SiO2显示文摘 | Luiz A M Cardoso Walter Alves Jr | 2004 | J Mol Catal A2004，209，12： | 1 |
| 13 | Rheological and physicochemical properties of starches from moist-and dry-type sweetpotatoes显示文摘 | WALTER W M Jr TRUONG V D WIESENBORN D P | 2000 | Journal of Agricultural and Food Chero-istry2000，48，7： | 1 |
| 14 | Copper, zinc manganese, and magnesium status and complications of diabetes mellitus 显示文摘 | Walter RM Jr Uriu-Hare JY Olin KL | 1991 | Diabetes Care1991，14，11： | 1 |
| 15 | Minor morbidity with emergency tourniquet use to stop bleeding in severe limb trauma:re-search,history,and reconciling advocates and abolitionists显示文摘 | Kragh JF Jr O'Neill ML Walters TJ | 2011 | Mil Med2011，176，7： | 1 |
| 16 | Ceramic-on-ceramic bearings in hip arthroplasty:state of the art and the future显示文摘 | Jeffers JR Walter WL | 2012 | J Bone Joint Surg Br2012，94，6： | 1 |
| 17 | Evi- dence for a second crystal form of polypropylene 显示文摘 | Keith H D Padden F J Jr Walter N M | 1959 | Applied Physics1959，30，12： | 1 |
| 18 | Economies of Scale and Organization Efficiency in Banking 显示文摘 | MORGAN J PRIMEAUX JR WALTER J | 1986 | Managerial & Decision Economics1986，7，4： | 1 |
| 19 | Pressure buildup analysis:with wellbore phase redistribution显示文摘 | Walter B Fair Jr | 1981 | SPEJ1981，21，： | 1 |
| 20 | Groin lymphorrhea complicating revascularization involving the femoral vessels显示文摘 | Walters GK Zenilman ME | 1993 | Am J Surg1993，165，3： | 1 |
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