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| 1 | Improvement of a High Velocity Compaction Technique for Iron Powder显示文摘Water atomized pure iron powder was compacted by high velocity compaction(HVC) with and without upper relaxation assist(URA) device.The influence of URA device on green density,spring back,green strength and hardness was studied.Morphological characteristics of the samples were observed by scanning electron microscope(SEM).Green strength of the samples was measured by computer controlled universal testing machine.The results show that as stroke length increases,the green density,green strength and hardness of the compacts increase gradually.At the identical stroke length,the green density of the compacts pressed with URA devise was 2% higher than the compacts pressed without URA device.The green strength and hardness of the compacts pressed with URA device were higher than the compacts pressed without URA device.Furthermore,the radial spring back of the compacts decreased gradually with the increment in stroke length,whilst that of compacts prepared with URA device was lower. | Dil Faraz KHAN Haiqing YIN Zahid USMAN Matiullah KHAN Xianjie YUAN Wenhao WANG Xuanhui QU | 2013 | Acta Metallurgica Sinica(English Letters)2013，26，4： | 4 |
| 2 | Arsenic trioxide overcomes apoptosis inhibition in K56z/ADM cells by regulating vital components in apoptotie pathway 显示文摘 | Wang Dil Wei IlL Zhao HS | 2005 | Pharrnacol Res2005，52，5： | 1 |
| 3 | Data-driven design of Ni-based turbine disc superalloys to improve yield strength显示文摘Increasing the thrust-weight ratio of aeroengines requires development of high-strength and stable high-temperature materials. A data-driven design of Ni-based turbine disc superalloys is performed to improve the yield strength to reach the target. Through first-principles calculations determining the design superalloy system, the theoretical models and Calculation of Phase Diagram (CALPHAD) screening compositions, and machine learning extrapolating prediction, 14 compositions are selected from 2,865,039 composition combinations. Ni-17Cr-8Co-1Mo-1W-6Al-3Ti-1Nb-1Ta is selected to verify the design accuracy. Experimental tests prove that the designed alloy has trade-offs of microstructure with satisfying design targets, and then, the yield strength is higher in the designed alloy than in commercial superalloys, reaching 728 MPa at 850 ℃. A scheme for increasing the performance of the designed alloy is proposed by discussing the strengthening mechanisms, machine learning process, and alloying chemistry effect. The cross-scale data-driven design is regarded as an accurate and efficient way to design novel high-strength Ni-based turbine disc superalloys, whose significance is the obvious reduction of trial-and-error tests. | Bin Xu Haiqing Yin Xue Jiang Cong Zhang Ruijie Zhang Yongwei Wang Xuanhui Qu Zhenghua Deng Guoqiang Yang Dil Faraz Khan | 2023 | Journal of Materials Science & Technology2023，，24： | 0 |
| 4 | Metabolomics of Fuzi-Gancao in CCl4 induced acute liver injury and its regulatory effect on bile acid profile in rats显示文摘BACKGROUND Fuzi(Radix aconiti lateralis)-Gancao(Radix glycyrrhizae)is one of the most classical drug pairs of traditional Chinese medicine.In clinical practice,decoctions containing Fuzi-Gancao(F-G)are often used in the treatment of liver diseases such as hepatitis and liver failure.AIM To investigate the metabolomics of F-G in CCl4 induced acute liver injury in rats and its regulatory effect on the bile acid profile.METHODS The pharmacodynamic effect of F-G on CCl4 induced acute liver injury in rats was evaluated,and an ultra performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)method for the simultaneous determination of 92 metabolites from multiple pathways was established to explore the protective metabolic mechanism of F-G in serum on the liver.RESULTS Twenty-four differential metabolites were identified in serum samples.The primary bile acid biosynthetic metabolic pathway was the major common pathway in the model group and F-G group.Subsequently,a UPLC-MS/MS method for simultaneous determination of 11 bile acids,including cholic acid,ursodeoxycholic acid,glycochenodeoxycholic acid,glycochenodeoxycholic acid,taurocholic acid,glycocholic acid,chenodeoxycholic acid,deoxycholic acid,taurochenodeoxycholic acid,taurocholic acid,and glycinic acid,was established to analyze the regulatory mechanism of F-G in serum.F-G decreased the contents of these 11 bile acids in serum in a dose-dependent manner compared with those in the model control group.CONCLUSION F-G could protect hepatocytes by promoting the binding of free bile acids to glycine and taurine,and reducing the accumulation of free bile acids in the liver.F-G could also regulate the compensatory degree of taurine,decreasing the content of taurine-conjugated bile acids to protect hepatocytes. | Mo-Fei Wang Song-Song Zhao Dil Momin Thapa Yu-Ling Song Zheng Xiang | 2021 | World Journal of Gastroenterology2021，27，40： | 0 |
| 5 | Neighborhood topological effect on grain topology-size relationship in three-dimensional polycrystalline microstructures显示文摘A new grain topology-size relationship in three-dimensional(3D)polycrystalline microstructures has recently been established by considering the effects of non-random first nearest neighbor grains.In this contribution,a generalized form for this relationship is presented by considering the interactions of kth(k=1,2,3…)nearest neighbor grains,and large scale Monte Carlo-Potts model simulation is used to investigate the general neighborhood topological effect on the topology-size relationship.The results show that,unlike their first nearest neighbors(k=1),the topological correlations of 3D grains with their kth layers(k 2)of nearest-neighbors may have trivial effect on the topology-size relationship. | ASAD Ullah LIU GuoQuan WANG Hao MATIULLAH Khan DIL Faraz Khan M ZUBAIR Iqbal | 2013 | Chinese Science Bulletin2013，58，30： | 0 |
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