5篇
您的检索式：作者名="Wang Minxin"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 显示文摘 | Wang Minxin Zhu Shuquan He Xuwen | 2001 | Journal of China University of Mining & Technology2001，11，2： | 1 |
| 2 | Study on micro electrolysis treatment for colorizing dyed water 显示文摘 | Wang Minxin | 2001 | Journal of China University Mining and Technology2001，11，2： | 1 |
| 3 | Study on Micro Electrolysis Treatment for Decolorizing Dyed Water显示文摘 | Wang Minxin Zhu Shuquan He Xuwen | 2001 | Jour CUNT2001，11，2： | 1 |
| 4 | New Metabolic Alterations and A Predictive Marker Pipecolic Acid in Sera for Esophageal Squamous Cell Carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC)is a major histological subtype of esophageal cancer with a poor prognosis.Although several serum metabolomic investigations have been reported,ESCC tumor-associated metabolic alterations and predictive biomarkers in sera have not been defined.Here,we enrolled 34 treatment-naive patients with ESCC and collected their pre-and post-esophagectomy sera together with the sera from 34 healthy volunteers for a metabolomic survey.Our comprehensive analysis identified ESCC tumor-associated metabolic alterations as represented by a panel of 12 serum metabolites.Notably,postoperative abrosia and parenteral nutrition substantially perturbed the serum metabolome.Furthermore,we performed an examination using sera from carcinogen-induced mice at the dysplasia and ESCC stages and identified three ESCC tumor-associated metabolites conserved between mice and humans.Notably,among these metabolites,the level of pipecolic acid was observed to be progressively increased in mouse sera from dysplasia to cancerization,and it could be used to accurately discriminate between mice at the dysplasia stage and healthy control mice.Furthermore,this metabolite is essential for ESCC cells to restrain oxidative stress-induced DNA damage and cell proliferation arrest.Together,this study revealed a panel of 12 ESCC tumor-associated serum metabolites with potential for monitoring therapeutic efficacy and disease relapse,presented evidence for refining parenteral nutrition composition,and highlighted serum pipecolic acid as an attractive biomarker for predicting ESCC tumorigenesis. | Lei Liu Jia Wu Minxin Shi Fengying Wang Haimin Lu Jibing Liu Weiqin Chen Guanzhen Yu Dan Liu Jing Yang Qin Luo Yan Ni Xing Jin Xiaoxia Jin Wen-Lian Chen | 2022 | Genomics, Proteomics & Bioinformatics2022，20，4： | 0 |
| 5 | GOLM1 suppresses autophagy-mediated anti-tumor immunity in hepatocellular carcinoma显示文摘Dear Editor,Immune-mediated tumor elimination depends on the production of cytokines and the recruitment of immune cells in the tumor microenvironment.Cell death-related signals such as ATP release from tumor cells are crucial for the activation of downstream immune responses.^(1)GOLM1,also known as GOLPH2 and GP73 as a Golgi transmembrane protein involved in the transport of protein cargo through the Golgi apparatus has been extensively studied in various cancers for its multifunctional roles in promoting cancer proliferation and metastasis through the AKT/mTOR pathway. | Tianqi Sui Xiaoyang Wang Lili Li Junxiao Liu Nan Qiao Lihua Duan Minxin Shi Jianfei Huang Heng Yang Genhong Cheng | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员