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| 1 | High shear stress induces atherosclerotic vulnerable plaque formation through angiogenesis显示文摘Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary syndrome and ischemic strokes.Inhibition of thrombosis is one of the important tasks developing biomedical materials such as intravascular stents and vascular grafts.Shear stress(SS)influences the formation and development of atherosclerosis.The current review focuses on the vulnerable plaques observed in the high shear stress(HSS)regions,which localizes at the proximal region of the plaque intruding into the lumen.The vascular outward remodelling occurs in the HSS region for vascular compensation and that angiogenesis is a critical factor for HSS which induces atherosclerotic vulnerable plaque formation.These results greatly challenge the established belief that low shear stress is important for expansive remodelling,which provides a new perspective for preventing the transition of stable plaques to high-risk atherosclerotic lesions. | Yi Wang Juhui Qiu Shisui Luo Xiang Xie Yiming Zheng Kang Zhang Zhiyi Ye Wanqian Liu Hans Gregersen GuixueWang | 2016 | Regenerative Biomaterials2016，3，4： | 8 |
| 2 | Hydrogen Production with High Evolution Rate and High Yield by Immobilized Cells of Hydrogen-producing Bacteria Strain B49 in a Column Reactor显示文摘To improve the hydrogen evolution rate in continuous hydrogen production of a novel fermentative hydrogen producing bacteria strain B49 (AF481148 in EMBL), 4 % immobilized cells by polyvinyl alcohol boric acid method, with the addition of a small amount of calcium alginate in a column reactor obtain hydrogen yield of 2.31 mol H2/mol glucose and hydrogen evolution rate of 1435.4 ml/L culture·h respectively at medium retention time of 2.0 h with a medium containing 10g glucose/L. Moreover, as the cell density in gel beads is increased to 8%, hydrogen yield and hydrogen evolution rate for 10g glucose/L are 2.34 mol H2/mol glucose and 2912.4 ml/L culture·h respectively at medium retention time of 1.0 h, and for molasses wastewater COD of 7505.9 mg/L hydrogen production potential of 205.6 ml/g COD and hydrogen evolution rate of 2057.7 ml/L culture·h at hydraulic retention time of 0.75 h are observed. In the continuous culture pH value keeps around 3.9 by self regulating. | 任南琪 Wang Xiangjing Xiang Wensheng Lin Ming Li Jianzheng Guo Wanqian | 2002 | High Technology Letters2002，8，4： | 6 |
| 3 | The start-up of biohydrogen-producing process by bioaugmentation in the EGSB reactor显示文摘 | 王相晶 Ren Nanqi Xiang Wensheng Guo Wanqian | 2006 | High Technology Letters2006，12，3： | 5 |
| 4 | Partial Characteristics of Hydrogen Production by Fermentative Hydrogen-producing Bacterial Strain B49显示文摘To investigate the characteristics of hydrogen production by a novel fermentative hydrogen-producing bacterial strain B49 (AF481148 in EMBL), batch experiments are conducted under different conditions. Hydrogen production has a correlation with cell growth and the consumption of glucose and soluble protein. The optimum pH for cell growth is 4.5±0.15. At acidic pH 4.0±0.15, the bacteria has the maximum accumulated hydrogen volume of 2382 ml/L culture and the maximum hydrogen evolution rate of 339.9 ml/L culture·h with 1% glucose. The optimum temperature for cell growth and hydrogen production is 35℃. In addition, fermentative hydrogen-producing bacterial strain B49 can generate hydrogen from the decomposition of other organic substrates such as wheat, soybean, corn, and potato. Moreover, it can also produce hydrogen from molasses wastewater and brewage wastewater, and hydrogen yields are 137.9 ml H 2/g COD and 49.9 ml H 2/g COD, respectively. | 王相晶 Ren Nanqi Xiang Wensheng Lin Ming Guo Wanqian | 2003 | High Technology Letters2003，9，3： | 5 |
| 5 | In vivo degradation and endothelialization of an iron bioresorbable scaffold显示文摘Detection of in vivo biodegradation is critical for development of next-generation medical devices such as bioresorbable stents or scaffolds(BRSs).In particular,it is urgent to establish a nondestructive approach to examine in vivo degradation of a new-generation coronary stent for interventional treatment based on mammal experiments;otherwise it is not available to semi-quantitatively monitor biodegradation in any clinical trial.Herein,we put forward a semi-quantitative approach to measure degradation of a sirolimus-eluting iron bioresorbable scaffold(IBS)based on optical coherence tomography(OCT)images;this approach was confirmed to be consistent with the present weight-loss measurements,which is,however,a destructive approach.The IBS was fabricated by a metal-polymer composite technique with a polylactide coating on an iron stent.The efficacy as a coronary stent of this new bioresorbable scaffold was compared with that of a permanent metal stent with the name of trade mark Xience,which has been widely used in clinic.The endothelial coverage on IBS was found to be greater than on Xience after implantation in a rabbit model;and our well-designed ultrathin stent exhibited less individual variation.We further examined degradation of the IBSs in both minipig coronary artery and rabbit abdominal aorta models.The present result indicated much faster iron degradation of IBS in the rabbit model than in the porcine model.The semi-quantitative approach to detect biodegradation of IBS and the finding of the species difference might be stimulating for fundamental investigation of biodegradable implants and clinical translation of the next-generation coronary stents. | Wenjiao Lin Hongjie Zhang Wanqian Zhang Haiping Qi Gui Zhang Jie Qian Xin Li Li Qin Haifeng Li Xiang Wang Hong Qiu Xiaoli Shi Wei Zheng Deyuan Zhang Runlin Gao Jiandong Ding | 2021 | Bioactive Materials2021，6，4： | 3 |
| 6 | Biohydrogen Production rate from ethanol-type fermentation of molasses in an expanded granular sludge bed (EGSB) reactor显示文摘 | GUO Wanqian REN Nanqi WANG Xiangjing | 2008 | Int J Hydrogen Energy2008，33，19： | 1 |
| 7 | Siultaneous biohydrogen production and starch wastewater treatment in an acidogenic expanded granular sludge bed reactor by mixed culture for long-term operation 显示文摘 | GUO Wanqian REN Nanqi CHEN Zhaobo | 2008 | Int J Hydrogen Energy2008，33，24： | 1 |
| 8 | Biological hydrogen production from organic wastewater by dark fermentation in China: Overview and prospects显示文摘 | Ren Nanqi Guo Wanqian Liu Bingfeng | 2009 | Frontiers of Environmental Science and Engineering in China2009，3，4： | 1 |
| 9 | Biohydrogenproduction from ethanol- type fermentation of molasses in anexpanded granular sludge bed (EGSB) reactor显示文摘 | Guo Wanqian Ren Nanqi Wang Xiangjing | 2008 | InternationalJournal of Hydrogen Energy2008，33，19： | 1 |
| 10 | Scale-up and optimization of biohydrogen production reactor from laboratory-scale to industrial- scale on the basis of computational fluid dynamics simulation 显示文摘 | WANG Xu DING Jie GUO Wanqian | 2010 | International journal of hydrogen energy2010，35，10： | 1 |
| 11 | The effect of hutyrate concentration on photo-hydrogen production from acetate by Rhodopseudornonas faecalis RLD-53 显示文摘 | Ren Nanqi Liu Bingfeng Ding Jie Guo Wanqian Cao Guangli Xie Guojun | 2008 | International Journal of Hydrogen Energy2008，33，： | 1 |
| 12 | Effects of different pretreatment methods on fermentation types and dominant bacteria for hydrogen production显示文摘 | REN Nanqi GUO Wanqian WANG Xiangjing | 2008 | International Journal of Hydrogen Energy2008，33，16： | 1 |
| 13 | Biohydrogen production from ethanol-type fermentation of molasses in an expanded granular sludge bed (EGSB) reactor显示文摘 | GUO Wanqian REN Nanqi WANG Xiangjing | 2008 | International Journal of Hydrogen Energy2008，33，19： | 1 |
| 14 | Minimization of excess sludge production by in-situ activated sludge treatment processes - a comprehensive review显示文摘 | GUO Wanqian YANG Shanshan XIANG Wensheng | 2013 | Bio- technology Advances2013，31，8： | 1 |
| 15 | Feasibility studies on continuous hydrogen production using photo-fermentative sequencing batch reactor显示文摘 | XIE Guojun LIU Bingfeng GUO Wanqian | 2012 | International Journal of Hydrogen Energy2012，37，13： | 1 |
| 16 | Possible caus- es of excess sludge reduction adding metabolic uncoupler,3,3' , 4', 5 -tetrachlorosalicylanilide (TCS),in sequence batch reactors 显示文摘 | Fang Xiaochi Guo Wanqian Yang Shanshan | 2014 | Bioresource Technology2014，173，： | 1 |
| 17 | Biological hydrogen production by dark fermentation: challenges and prospects towards scaled-up production显示文摘 | Nanqi Ren Wanqian Guo Bingfeng Liu Guangli Cao Jie Ding | 2011 | Current Opinion in Biotechnology2011，，3： | 1 |
| 18 | Optimization of culture conditions for hydrogen production by Ethanoligenens harbinense B49 using response surface methodology显示文摘 | GUO Wanqian REN Nanqi WANG Xiangjing | 2009 | Bioresource technology2009，100，3： | 1 |
| 19 | Minimization of excess sludge production by in-situ activated sludge treatment processes: a comprehensive review 显示文摘 | GUO Wanqian YANG Shanshan XIANG Wensheng | 2013 | Biotechnology Advances2013，31，8： | 1 |
| 20 | Effect of chemical and physical factors to improve the germination rate of Echinacea angustifolia seeds 显示文摘 | Duan CR Wang BC Liu Wanqian | 2004 | Colloids and Surfaces B:Biointerfaces2004，37，： | 1 |
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