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| 1 | Post-mortem tissue proteomics reveals the pathogenesis of multi-organ injuries of COVID-19显示文摘Multi-organ injuries are a major complication of severe Coronavirus Disease 2019(COVID-19).However,its pathogenesis is barely understood.Herein;we profile host responses to fatal SARS-CoV-2 infection by performing quantitative proteomics of 19 post-mortem samples of 8 different organs or tissues,including lungs,liver,intestine,kidney;spleen,brain,heart and muscle,from 3 deceased COVID-19 victims during the first wave of the pandemic(Supplementary Fig.S1A and B,Tables SI-S3). | Yang Qiu Di Wu Wanshan Ning Jiqian Xu Ting Shu Muhan Huang Rong Chen Jiancheng Zhang Yang Han Qingyu Yang Ruiting Li Xiaobo Yang Yaxin Wang Xiaojing Zou Shangwen Pan Chaolin Huang Yu Xue You Shang Xi Zhou | 2021 | National Science Review2021,8,11: | 1 |
| 2 | Research on rotary surface topography by orthogonal turn-milling显示文摘 | Zhu Lida Li Haonan Wang Wanshan | 2013 | The International Journal of Advanced Manufacturing Technology2013,69,9101112: | 1 |
| 3 | ADI-FDTDMethod for Two-Dimensional Transient Electromagnetic Problems显示文摘An efficient and accurate numerical scheme is proposed for solving the transverse electric(TE)mode electromagnetic(EM)propagation problemin two-dimensional earth.The scheme is based on the alternating direction finite-difference time-domain(ADI-FDTD)method.Unlike the conventional upward continuation approach for the earth-air interface,an integral formulation for the interface boundary is developed and it is effectively incorporated to the ADI solver.Stability and convergence analysis together with an error estimate are presented.Numerical simulations are carried out to validate the proposed method,and the advantage of the present method over the popular Du-Fort-Frankel scheme is clearly demonstrated.Examples of the electromagnetic field propagation in the ground with anomaly further verify the effectiveness of the proposed scheme. | Wanshan Li Yile Zhang Yau Shu Wong Dong Liang | 2016 | Communications in Computational Physics2016,19,1: | 0 |
| 4 | Bioinspired mineral-in-shell nanoarchitectonics:Functional empowerment of mineral precursors for guiding intradentinal mineralization显示文摘Effective mineralization of biological structures poses a significant challenge in hard tissue engineering as it necessitates overcoming geometric complexities and multistep biomineralization processes.In this regard,we propose“mineral-in-shell nanoarchitectonics”,inspired by the nanostructure of matrix vesicles,which can influence multiple mineralization pathways.Our nanostructural design empowers mineral precursors with tailorable properties through encapsulating amorphous calcium phosphate within a multifunctional tannic acid(TA)and silk fibroin(SF)nanoshell.The bioinspired nanosystem facilitates efficient recruitment of mineral precursors throughout the dentin structures,followed by large-scale intradentinal mineralization both in vitro and in vivo,which provides persistent protection against external stimuli.Theoretical simulations combined with experimental studies attribute the success of intradentinal mineralization to the TA-SF nanoshell,which exhibits a strong affinity for the dentin structure,stabilizing amorphous precursors and thereby facilitating concomitant mineral formation.Overall,this bioinspired mineral-in-shell nanoarchitectonics shows a promising prospect for hard tissue repair and serves as a blueprint for next-generation biomineralization-associated materials. | Xiaoran Zheng Yang Liu Mingjing Li Yuyan Li Wanshan Gao Rongmin Qiu Jiaqi Xing Jiaojiao Yang Yantao Chen Xinyuan Xu Mingming Ding Jun Luo Jianshu Li | 2024 | Nano Research2024,17,5: | 0 |
| 5 | Different Burial-Cooling History of Triassic Strata between the Western Weibei Uplift and the Northwestern Weihe Basin in Northwest China显示文摘Analysis of tectonothermal history of the Yanchang Formation in the western Weibei Uplift and in the northwestern Weihe Basin can reconstruct the cooling history of the southwest most remained Upper Triassic source rock of the North China Plate. Apatite fission-track(AFT) and(U-ThSm)/He(AHe) analysis were used to recover the cooling and uplift history of the Upper Triassic here. Ten sandstones from the Middle–Upper Triassic strata yield AFT ages between 179.8 ± 7.4 and 127.6 ± 8.1 Ma. AHe ages of two sandstones have the value of 37.7 ± 2.3–131.1 ± 8.1 and 45.7 ± 2.8–83.5 ± 5.2 Ma. Time-temperature modeling results showed that tectonothermal history of the Yanchang Formation was initially different in time-space relationships but then became almost identical through time followed by different cooling rate. Modeling results of the Triassic strata in the Qianyang area and the Yaojiagou area revealed three different uplift-cooling stages commencing in the Late Jurassic at ~165 Ma and in Early Cretaceous at ~110 Ma, respectively, both followed by first similar cooling histories to the Early Miocene at ~20 – 23 Ma and then different since the Late Miocene. Uplift-cooling rate since the Late Miocene at ~8 Ma were different between the Western Weibei Uplift and the Northwestern Weihe Basin. The timing, cooling-uplift rates of the Yaojiagou area, which was mainly controlled by movements related to the Liupanshan Mountains, the Qinling Orogens and the Weibei Uplift, had the earliest onset of uplift-cooling for the Upper Triassic series compared to other regions within the Weibei Uplift. Cooling paths for the Upper Triassic series became uniform regionally in the Early Cretaceous marking a key time for the tectonothermal evolutionary history of Upper Triassic series in the southwestern North China Plate. | Qiang Yu Zhanli Ren Rongxi Li Chung Ling Tao Ni Wanshan Lei Baojiang Wang Xiaoli Wu Xiaoli Qin Xianghe Lei | 2023 | Journal of Earth Science2023,34,5: | 0 |
| 6 | Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft显示文摘Tissue-engineered vascular grafts(TEVGs)have enormous potential for vascular replacement therapy.However,thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs(<6 mm)after transplantation.Endothelialization of TEVGs is a key point to prevent thrombosis.Here,we discuss different types of endothelialization and different seed cells of tissue-engineered vascular grafts.Meanwhile,endothelial heterogeneity is also discussed.Based on it,we provide a new perspective for selecting suitable types of endothelialization and suitable seed cells to improve the long-term patency rate of tissue-engineered vascular grafts with different diameters and lengths. | Qingjin Cai Wanshan Liao Fangchao Xue Xiaochen Wang Weiming Zhou Yanzhao Li Wen Zeng | 2021 | Bioactive Materials2021,6,8: | 0 |