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| 1 | Escitalopram a review of its use in the manage- ment of major depressive and anxiety disorders显示文摘 | Waugh J Coa K I | 2003 | CNS Drugs2003，17，5： | 1 |
| 2 | Detection and analysis of genetic variation in Hordeum spontaneum populations from Israel using RAPD makers显示文摘 | DAWSON I K CHALMER K J WAUGH R | 1993 | Mol Ecol1993，2，： | 1 |
| 3 | Birth weight and 24-hour ambulatory blood pressure in nonpro-teinuric hypertensive pregnancy显示文摘 | WAUGH J PERRY I J HALLIGAN A W | 2000 | Am J Obstet Gynecol2000，183，3： | 1 |
| 4 | Flexible emotional responsiveness in trait resilience显示文摘 | Waugh C E Thompson R J Gotlib I H | 2011 | Emotion2011，11，5： | 1 |
| 5 | Detection and analysis of genetic variation in Hordeum spontaneum populations from Israel using RAPD markers 显示文摘 | Dawson I K Chalmer K J Waugh R | 1993 | Mol Ecol1993，2，3： | 1 |
| 6 | Genome sequence and analysis of the tuber crop potato显示文摘 | Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G | 2011 | Nature2011，475，7355： | 1 |
| 7 | Flexible emotional responsive-ness in trait resilience显示文摘 | Waugh C E Thompson R J Gotlib I H | 2011 | Emotion2011，11，5： | 1 |
| 8 | Detection and analysis of genetic variation in Hordeum spontaneum populations from Israel using RAPD markers显示文摘 | Dawson I K Chalmers K J Waugh R | 1993 | Molecular Ecology1993，2，： | 1 |
| 9 | Zinc oxide thin films grown by aerosol assisted CVD显示文摘 | Waugh M R Hyett G Parkin I P | 2008 | Chemical Vapor Deposition2008，14，11： | 1 |
| 10 | Fasting-induced adipose factor identified as a key adipokine that is up-regulated in white adipose tissue during pregnancy and lactation in the rat 显示文摘 | Josephs T Waugh H Kokay I | 2007 | Journal of Endocrinology2007，194，： | 1 |
| 11 | Birth weight and 24-hour ambulatory blood pressure in nonproteinuric hypertensive pregnancy 显示文摘 | Waugh J Perry I Halligan A | 2000 | Am J Obstet Gynecol2000，183，3： | 1 |
| 12 | The elasticity of trade: estimates and evidence 显示文摘 | SIMONOVSKA I WAUGH M | 2014 | Journal of International Economics2014，16，1： | 1 |
| 13 | , Detection and analysis of genetic variation in Hordeum spontaneum populations from Israel using RAPDmarkers显示文摘 | Chalmer K J Waugh R | 1993 | Mol Ecol1993，2，： | 1 |
| 14 | Triggering, bypass transi - tion and the effect of noise on a linearly stable thermo - acoustic system 显示文摘 | Waugh I Geuss M J Juniper M | 2011 | Proceedings of the Combustion Institute2011，33，： | 1 |
| 15 | Detection and analysis of genetic variation in Hordeum spontaneum populations from Israel using RAPD markers 显示文摘 | Dawson I K Chalmer K J Waugh R | 1993 | Mol Ecol1993，2，： | 1 |
| 16 | Triggering in a thermoacoustic system with stochastic noise显示文摘 | Waugh I C Juniper M P | 2011 | International Journal of Spray and Combustion Dynamics2011，3，3： | 1 |
| 17 | Flexible emotional responsive- ness in trait resilience 显示文摘 | Waugh C E Thompson R J Gotlib I H | 2011 | Emotion2011，11，5： | 1 |
| 18 | Detection and analysis of genetic variation in Hordeum spontaneum population from Israel using RAPD markers 显示文摘 | Dawson I K Chalmers K J Waugh R | 1993 | Molecular Ecology1993，2，： | 1 |
| 19 | Flexible emotional respon- siveness in trait resilience 显示文摘 | Waugh C E Thompson R J Gotlib I H | 2011 | Emotion2011，11，5： | 1 |
| 20 | Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation显示文摘AIM:To investigate genetic differences between Crohn's disease(CD) patients with a sustained remission vs relapsers after discontinuing infliximab while in corticosteroid-free remission.METHODS:Forty-eight CD patients received infliximab and were in full corticosteroid-free clinical remission but then discontinued infliximab for reasons other than a loss of response,were identified by review of an electronic database and charts.Infliximab-associated remission was defined as corticosteroid-free plus normalization of clinical disease activity [CD activity index(CDAI) < 150] during follow-up visits based on physician global assessments.A CD relapse(loss of infliximab-induced remission) was clinically defined as a physician visit for symptoms of disease activity(CDAI > 220) and a therapeutic intervention with CD medication(s),or a hospitalization with complications related to active CD.Genetic analyses were performed on samples from 14 patients(n = 6 who had a sustained long term remission after stopping infliximab,n = 8 who rapidly relapsed after stopping infliximab).Nucleotide-binding oligomerization domain 2(NOD2)/caspase activation recruitment domain 15(CARD15) polymorphisms(R702W,G908R and L1007fs) and the inflammatory bowel disease 5(IBD5) polymorphisms(IGR2060a1 and IGR3081a1) were analyzed in each group.RESULTS:Five single nucleotide polymorphisms of IBD5 and NOD2/CARD15 genes were successfully analyzed for all 14 subjects.There was no significant increase in frequency of the NOD2/CARD15 polymorphisms(R702W,G908R and L1007fs) and the IBD5 polymorphisms(IGR2060a1 and IGR3081a1) in either group of patients;those whose disease relapsed rapidly or those who remained in sustained long term remission following the discontinuation of infliximab.Nearly a third of patients in full clinical remission who stopped infliximab for reasons other than loss of response remained in sustained clinical remission,while two-thirds relapsed rapidly.There was a marked difference in the duration of clinical remission following discontinuance of infliximab between the two groups.The patients who lost remission did so after 1.0 years ± 0.6 years,while those still in remission were at the time of this study,8.1 years ± 2.6 years post-discontinuation of infliximab,P < 0.001.The 8 patients who had lost remission after discontinuing infliximab had a mean number of 5 infusions(range 3-7),with a mean treatment time of 7.2 mo(range 1.5 mo-15 mo).The mean duration of time from the last infusion of infliximab to the time of loss of remission was 382 d(range 20 d-701 d).The 6 patients who remained in remission after discontinuing infliximab had a mean number of 6 infusions(range 3-12),with a mean treatment duration of 12 mo(range 3.6 mo-32 mo)(P = 0.45 relative to those who lost remission).CONCLUSION:There are no IBD5 or NOD2/CARD15 mutations that predict which patients might have sustained remission and which will relapse rapidly after stopping infliximab. | Cathy Lu Alistair Waugh Robert J Bailey Raeleen Cherry Levinus A Dieleman Leah Gramlich Kata Matic Mario Millan Karen I Kroeker Daniel Sadowski Christopher W Teshima Dennis Todoruk Clarence Wong Karen Wong Richard N Fedorak | 2012 | World Journal of Gastroenterology2012，18，36： | 1 |
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